Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM246608 (4-{4-[6-(4-(4-Bromophenyl)-3-cyano-2-imino)-1,2-di...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MSA University | Assay Description Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo... | J Enzyme Inhib Med Chem 29: 215-22 (2014) Article DOI: 10.3109/14756366.2013.765417 BindingDB Entry DOI: 10.7270/Q20C4TPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM246608 (4-{4-[6-(4-(4-Bromophenyl)-3-cyano-2-imino)-1,2-di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MSA University | Assay Description Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo... | J Enzyme Inhib Med Chem 29: 215-22 (2014) Article DOI: 10.3109/14756366.2013.765417 BindingDB Entry DOI: 10.7270/Q20C4TPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM246607 (HER2/EGFR dual kinase inhibitor, 5d) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MSA University | Assay Description Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo... | J Enzyme Inhib Med Chem 29: 215-22 (2014) Article DOI: 10.3109/14756366.2013.765417 BindingDB Entry DOI: 10.7270/Q20C4TPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM246609 ((E)-3-(4-Chlorophenyl)-1-{4-[(6,7-dimethoxyquinazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MSA University | Assay Description Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo... | J Enzyme Inhib Med Chem 29: 215-22 (2014) Article DOI: 10.3109/14756366.2013.765417 BindingDB Entry DOI: 10.7270/Q20C4TPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM246607 (HER2/EGFR dual kinase inhibitor, 5d) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MSA University | Assay Description Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo... | J Enzyme Inhib Med Chem 29: 215-22 (2014) Article DOI: 10.3109/14756366.2013.765417 BindingDB Entry DOI: 10.7270/Q20C4TPT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM246609 ((E)-3-(4-Chlorophenyl)-1-{4-[(6,7-dimethoxyquinazo...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
MSA University | Assay Description Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo... | J Enzyme Inhib Med Chem 29: 215-22 (2014) Article DOI: 10.3109/14756366.2013.765417 BindingDB Entry DOI: 10.7270/Q20C4TPT | |||||||||||
More data for this Ligand-Target Pair |