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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM67690 (1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Graduate School of Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli BL21(DE3) after 1 hr by HTRF assay | J Med Chem 56: 2619-29 (2013) Article DOI: 10.1021/jm400045y BindingDB Entry DOI: 10.7270/Q2125TZ0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM67690 (1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Graduate School of Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of BTK (unknown origin) | J Med Chem 56: 2619-29 (2013) Article DOI: 10.1021/jm400045y BindingDB Entry DOI: 10.7270/Q2125TZ0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 12 (Homo sapiens (Human)) | BDBM15244 (5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Graduate School of Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Binding affinity to p38gamma (unknown origin) | J Med Chem 56: 2619-29 (2013) Article DOI: 10.1021/jm400045y BindingDB Entry DOI: 10.7270/Q2125TZ0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM15244 (5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfa...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a |
Graduate School of Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Binding affinity to p38alpha (unknown origin) | J Med Chem 56: 2619-29 (2013) Article DOI: 10.1021/jm400045y BindingDB Entry DOI: 10.7270/Q2125TZ0 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
