Affinity Data by PubMed id=23453069

PubMed code 23453069

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM8726 (5-chloro-2-(2,4-dichlorophenoxy)phenol \| CHEMBL849...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM50431922 (5‐chloro‐2‐[2‐chloro‐...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc(cc1Cl)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM50431923 (5‐chloro‐2‐(naphthalen‐2&#...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc2ccccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM50431920 (5‐(4‐chloro‐2‐hydroxypheno...) Show SMILES Cc1cc(NC(=O)c2ccc(Oc3ccc(Cl)cc3O)o2)no1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM50431918 (CHEMBL2347828) Show SMILES Oc1cc(Cl)ccc1Oc1ccc2ncccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM50431921 (CHEMBL2347842) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM50431919 (CHEMBL2347830) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	965	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%