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PubMed code 23534475

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hexokinase type IV


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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UniChem
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n/an/a 4.00E+3n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 6.00E+3n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
TAK1/TAB1


(Homo sapiens (Human))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 1.10E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM93229
PNG
(Kinase inhibitor, F3)
Show SMILES Fc1ccccc1-c1cc(=O)n2cc[nH]c2n1
Show InChI InChI=1S/C12H8FN3O/c13-9-4-2-1-3-8(9)10-7-11(17)16-6-5-14-12(16)15-10/h1-7H,(H,14,15)
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n/an/a 1.40E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase CHK2


(Homo sapiens (Human))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 1.70E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Casein kinase II alpha


(Homo sapiens (Human))
BDBM93224
PNG
(Kinase inhibitor, A1)
Show SMILES CC1CN(CC(C)O1)c1nc2ccccn2c(=O)c1N
Show InChI InChI=1S/C14H18N4O2/c1-9-7-17(8-10(2)20-9)13-12(15)14(19)18-6-4-3-5-11(18)16-13/h3-6,9-10H,7-8,15H2,1-2H3
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n/an/a 1.80E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4


(Homo sapiens (Human))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 2.00E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Gallus gallus (Chicken))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 2.00E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 2.10E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
MAP kinase-activated protein kinase 3


(Homo sapiens (Human))
BDBM93224
PNG
(Kinase inhibitor, A1)
Show SMILES CC1CN(CC(C)O1)c1nc2ccccn2c(=O)c1N
Show InChI InChI=1S/C14H18N4O2/c1-9-7-17(8-10(2)20-9)13-12(15)14(19)18-6-4-3-5-11(18)16-13/h3-6,9-10H,7-8,15H2,1-2H3
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n/an/a 2.10E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PIM


(Homo sapiens (Human))
BDBM93229
PNG
(Kinase inhibitor, F3)
Show SMILES Fc1ccccc1-c1cc(=O)n2cc[nH]c2n1
Show InChI InChI=1S/C12H8FN3O/c13-9-4-2-1-3-8(9)10-7-11(17)16-6-5-14-12(16)15-10/h1-7H,(H,14,15)
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n/an/a 2.20E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
TAK1/TAB1


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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n/an/a 2.40E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM93227
PNG
(Kinase inhibitor, C2)
Show SMILES COc1ccc(cc1OC)-c1cc2c(nc[nH]c2=O)s1
Show InChI InChI=1S/C14H12N2O3S/c1-18-10-4-3-8(5-11(10)19-2)12-6-9-13(17)15-7-16-14(9)20-12/h3-7H,1-2H3,(H,15,16,17)
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK2


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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n/an/a 2.60E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM93226
PNG
(Kinase inhibitor, B1)
Show SMILES Nc1nc2cnc(cn2n1)-c1ccccc1
Show InChI InChI=1S/C11H9N5/c12-11-14-10-6-13-9(7-16(10)15-11)8-4-2-1-3-5-8/h1-7H,(H2,12,15)
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n/an/a 3.90E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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n/an/a 4.70E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Gallus gallus (Chicken))
BDBM93224
PNG
(Kinase inhibitor, A1)
Show SMILES CC1CN(CC(C)O1)c1nc2ccccn2c(=O)c1N
Show InChI InChI=1S/C14H18N4O2/c1-9-7-17(8-10(2)20-9)13-12(15)14(19)18-6-4-3-5-11(18)16-13/h3-6,9-10H,7-8,15H2,1-2H3
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n/an/a 9.70E+4n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Sgk1


(Homo sapiens (Human))
BDBM93227
PNG
(Kinase inhibitor, C2)
Show SMILES COc1ccc(cc1OC)-c1cc2c(nc[nH]c2=O)s1
Show InChI InChI=1S/C14H12N2O3S/c1-18-10-4-3-8(5-11(10)19-2)12-6-9-13(17)15-7-16-14(9)20-12/h3-7H,1-2H3,(H,15,16,17)
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n/an/a 1.10E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase SRPK1


(Homo sapiens (Human))
BDBM93224
PNG
(Kinase inhibitor, A1)
Show SMILES CC1CN(CC(C)O1)c1nc2ccccn2c(=O)c1N
Show InChI InChI=1S/C14H18N4O2/c1-9-7-17(8-10(2)20-9)13-12(15)14(19)18-6-4-3-5-11(18)16-13/h3-6,9-10H,7-8,15H2,1-2H3
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n/an/a 1.14E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Casein kinase II alpha


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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n/an/a 1.31E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM93228
PNG
(Kinase inhibitor, D1)
Show SMILES CC(C)(C)Nc1c([nH]c2ncnn12)C1CC1
Show InChI InChI=1S/C11H17N5/c1-11(2,3)15-9-8(7-4-5-7)14-10-12-6-13-16(9)10/h6-7,15H,4-5H2,1-3H3,(H,12,13,14)
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n/an/a 1.58E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Aurora kinase A


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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n/an/a 1.88E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM93224
PNG
(Kinase inhibitor, A1)
Show SMILES CC1CN(CC(C)O1)c1nc2ccccn2c(=O)c1N
Show InChI InChI=1S/C14H18N4O2/c1-9-7-17(8-10(2)20-9)13-12(15)14(19)18-6-4-3-5-11(18)16-13/h3-6,9-10H,7-8,15H2,1-2H3
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n/an/a 1.96E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM93225
PNG
(Kinase inhibitor, A2)
Show SMILES Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)|
Show InChI InChI=1S/C14H9F2N3O/c15-9-4-1-5-10(16)12(9)8-3-2-6-19-13(8)18-7-11(17)14(19)20/h1-7H,17H2
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n/an/a 2.52E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM93228
PNG
(Kinase inhibitor, D1)
Show SMILES CC(C)(C)Nc1c([nH]c2ncnn12)C1CC1
Show InChI InChI=1S/C11H17N5/c1-11(2,3)15-9-8(7-4-5-7)14-10-12-6-13-16(9)10/h6-7,15H,4-5H2,1-3H3,(H,12,13,14)
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n/an/a 4.69E+5n/an/an/an/an/an/a



University of Dundee



Assay Description
Selected compounds were screened against a panel of mammalian kinases. Compounds were supplied in DMSO and screened in duplicates at 100 uM concentr...


ACS Chem Biol 8: 1044-52 (2013)


Article DOI: 10.1021/cb300729y
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%