Affinity Data by PubMed id=23566315

PubMed code 23566315

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human))	BDBM50327696 (2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide \| CHE...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of recombinant ICMT (unknown origin) expressed in sf9 cells using biotin S-farnesyl-L-cysteine as substrate				J Med Chem 56: 5219-30 (2014) Article DOI: 10.1021/jm3017706 BindingDB Entry DOI: 10.7270/Q2GB25F2
The University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
GTPase KRas (Homo sapiens (Human))	BDBM50436053 (CHEMBL2396992) Show SMILES Cc1[nH]c2cc(Cl)cc(Cl)c2c1CCN Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of SOS-mediated nucleotide release activity				J Med Chem 56: 5219-30 (2014) Article DOI: 10.1021/jm3017706 BindingDB Entry DOI: 10.7270/Q2GB25F2
The University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
GTPase KRas (Homo sapiens (Human))	BDBM50436053 (CHEMBL2396992) Show SMILES Cc1[nH]c2cc(Cl)cc(Cl)c2c1CCN Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Arizona Curated by ChEMBL					Assay Description Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of nucleotide exchange activity				J Med Chem 56: 5219-30 (2014) Article DOI: 10.1021/jm3017706 BindingDB Entry DOI: 10.7270/Q2GB25F2
The University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%