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PubMed code 23566514

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50434377
PNG
(CHEMBL2387002)
Show SMILES CC(C)n1cc(C(=O)c2cccc(NC(=O)Nc3ccc(Cl)cc3)c2)c2c(N)ncnc12
Show InChI InChI=1S/C23H21ClN6O2/c1-13(2)30-11-18(19-21(25)26-12-27-22(19)30)20(31)14-4-3-5-17(10-14)29-23(32)28-16-8-6-15(24)7-9-16/h3-13H,1-2H3,(H2,25,26,27)(H2,28,29,32)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDGFR (unknown origin)


Bioorg Med Chem Lett 23: 3059-63 (2013)


Article DOI: 10.1016/j.bmcl.2013.03.012
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50434378
PNG
(CHEMBL2386994)
Show SMILES Nc1ncnc2n(cc(C(=O)c3cccc(NC(=O)Nc4c(F)cccc4F)c3)c12)C1CCCC1
Show InChI InChI=1S/C25H22F2N6O2/c26-18-9-4-10-19(27)21(18)32-25(35)31-15-6-3-5-14(11-15)22(34)17-12-33(16-7-1-2-8-16)24-20(17)23(28)29-13-30-24/h3-6,9-13,16H,1-2,7-8H2,(H2,28,29,30)(H2,31,32,35)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDGFR (unknown origin)


Bioorg Med Chem Lett 23: 3059-63 (2013)


Article DOI: 10.1016/j.bmcl.2013.03.012
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%