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PubMed code 23621789

Compile data set for download or QSAR
Found 69 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432712
PNG
(AM4089 | CHEMBL2348473)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(CO)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3-4,8-10,16-18,27-28H,5-7,11-14H2,1-2H3
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2.10n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432714
PNG
(AM4054 | CHEMBL2348462)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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4.90n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432730
PNG
(CHEMBL2348459)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CC[C@@H]12)C=O)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,14-18,20-21,28H,3-8,11-13H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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5.5n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50169951
PNG
((6aR,10aR)-3-Adamantan-1-yl-6,6,9-trimethyl-6a,7,1...)
Show SMILES CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,t:1,TLB:11:18:21.20.25:23,THB:19:20:23:27.18.26,19:18:21.20.25:23,11:18:21:25.24.23,26:18:21:25.24.23,26:24:21:27.19.18|
Show InChI InChI=1S/C26H34O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4,10-11,16-18,20-21,27H,5-9,12-14H2,1-3H3/t16?,17?,18?,20-,21-,26?/m1/s1
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6.80n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432713
PNG
(CHEMBL2348472)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(CO)=CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,c:16,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3,9-10,16-18,20-21,27-28H,4-8,11-14H2,1-2H3/t16?,17?,18?,20-,21-,26?/m1/s1
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7.20n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432720
PNG
(CHEMBL2348469)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CC=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H36O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h6,11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21-,22-,27?/m1/s1
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7.80n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432720
PNG
(CHEMBL2348469)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CC=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H36O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h6,11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21-,22-,27?/m1/s1
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8.10n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432722
PNG
(CHEMBL2348467)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CCO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H38O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,28-29H,3-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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8.60n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432729
PNG
(CHEMBL2348460)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC[C@@H]12)C=O)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,14-18,20-21,28H,3-8,11-13H2,1-2H3/t15-,16?,17?,18?,20+,21+,26?/m0/s1
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9n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432714
PNG
(AM4054 | CHEMBL2348462)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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11n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432713
PNG
(CHEMBL2348472)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(CO)=CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,c:16,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3,9-10,16-18,20-21,27-28H,4-8,11-14H2,1-2H3/t16?,17?,18?,20-,21-,26?/m1/s1
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11n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432723
PNG
(CHEMBL2348466)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H36O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h6,11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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11n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432714
PNG
(AM4054 | CHEMBL2348462)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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12n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432723
PNG
(CHEMBL2348466)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H36O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h6,11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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13n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432713
PNG
(CHEMBL2348472)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(CO)=CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,c:16,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3,9-10,16-18,20-21,27-28H,4-8,11-14H2,1-2H3/t16?,17?,18?,20-,21-,26?/m1/s1
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14n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432718
PNG
(CHEMBL2348471)
Show SMILES CC(C)(C)C(=O)OCC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,t:8,THB:30:29:26:32.31.33,30:31:28.29.34:26,33:31:28:34.25.26,33:25:28:32.30.31|
Show InChI InChI=1S/C31H42O4/c1-29(2,3)28(33)34-17-18-6-7-24-23(11-18)27-25(32)12-22(13-26(27)35-30(24,4)5)31-14-19-8-20(15-31)10-21(9-19)16-31/h6,12-13,19-21,23-24,32H,7-11,14-17H2,1-5H3/t19?,20?,21?,23-,24-,31?/m1/s1
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17n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432720
PNG
(CHEMBL2348469)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CC=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H36O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h6,11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21-,22-,27?/m1/s1
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18n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432729
PNG
(CHEMBL2348460)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC[C@@H]12)C=O)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,14-18,20-21,28H,3-8,11-13H2,1-2H3/t15-,16?,17?,18?,20+,21+,26?/m0/s1
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20n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432719
PNG
(CHEMBL2348470)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CCO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H38O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,28-29H,3-10,13-15H2,1-2H3/t16-,17?,18?,19?,21-,22-,27?/m1/s1
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21n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432728
PNG
(CHEMBL2348461)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H34O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,18-20,26-27H,3-7,10-13H2,1-2H3/t14?,15?,16?,18-,19-,20-,25?/m1/s1
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24n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432730
PNG
(CHEMBL2348459)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CC[C@@H]12)C=O)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,14-18,20-21,28H,3-8,11-13H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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26n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432721
PNG
(CHEMBL2348468)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20+,21+,26?/m0/s1
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30n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432724
PNG
(CHEMBL2348465)
Show SMILES CO\C=C/[C@@H]1CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,THB:26:25:22:28.27.29,26:27:24.25.30:22,29:27:24:30.21.22,29:21:24:28.26.27|
Show InChI InChI=1S/C28H38O3/c1-27(2)23-5-4-17(6-7-30-3)11-22(23)26-24(29)12-21(13-25(26)31-27)28-14-18-8-19(15-28)10-20(9-18)16-28/h6-7,12-13,17-20,22-23,29H,4-5,8-11,14-16H2,1-3H3/b7-6-/t17-,18?,19?,20?,22+,23+,28?/m0/s1
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31n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432712
PNG
(AM4089 | CHEMBL2348473)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(CO)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3-4,8-10,16-18,27-28H,5-7,11-14H2,1-2H3
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32n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432722
PNG
(CHEMBL2348467)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CCO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H38O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,28-29H,3-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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33n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432723
PNG
(CHEMBL2348466)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H36O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h6,11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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34n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432722
PNG
(CHEMBL2348467)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CCO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H38O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,28-29H,3-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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38n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432728
PNG
(CHEMBL2348461)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H34O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,18-20,26-27H,3-7,10-13H2,1-2H3/t14?,15?,16?,18-,19-,20-,25?/m1/s1
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39n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432719
PNG
(CHEMBL2348470)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CCO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H38O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,28-29H,3-10,13-15H2,1-2H3/t16-,17?,18?,19?,21-,22-,27?/m1/s1
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41n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432728
PNG
(CHEMBL2348461)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H34O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,18-20,26-27H,3-7,10-13H2,1-2H3/t14?,15?,16?,18-,19-,20-,25?/m1/s1
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41n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432717
PNG
(CHEMBL2348474)
Show SMILES Cc1ccc2c(c1)-c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C26H30O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4-6,10-11,16-18,27H,7-9,12-14H2,1-3H3
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42n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432712
PNG
(AM4089 | CHEMBL2348473)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(CO)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3-4,8-10,16-18,27-28H,5-7,11-14H2,1-2H3
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47n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432729
PNG
(CHEMBL2348460)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC[C@@H]12)C=O)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,14-18,20-21,28H,3-8,11-13H2,1-2H3/t15-,16?,17?,18?,20+,21+,26?/m0/s1
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48n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432718
PNG
(CHEMBL2348471)
Show SMILES CC(C)(C)C(=O)OCC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,t:8,THB:30:29:26:32.31.33,30:31:28.29.34:26,33:31:28:34.25.26,33:25:28:32.30.31|
Show InChI InChI=1S/C31H42O4/c1-29(2,3)28(33)34-17-18-6-7-24-23(11-18)27-25(32)12-22(13-26(27)35-30(24,4)5)31-14-19-8-20(15-31)10-21(9-19)16-31/h6,12-13,19-21,23-24,32H,7-11,14-17H2,1-5H3/t19?,20?,21?,23-,24-,31?/m1/s1
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49n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432725
PNG
(CHEMBL2348464)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC#N)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H35NO2/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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49n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50169951
PNG
((6aR,10aR)-3-Adamantan-1-yl-6,6,9-trimethyl-6a,7,1...)
Show SMILES CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,t:1,TLB:11:18:21.20.25:23,THB:19:20:23:27.18.26,19:18:21.20.25:23,11:18:21:25.24.23,26:18:21:25.24.23,26:24:21:27.19.18|
Show InChI InChI=1S/C26H34O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4,10-11,16-18,20-21,27H,5-9,12-14H2,1-3H3/t16?,17?,18?,20-,21-,26?/m1/s1
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52n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432730
PNG
(CHEMBL2348459)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CC[C@@H]12)C=O)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,14-18,20-21,28H,3-8,11-13H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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53n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432717
PNG
(CHEMBL2348474)
Show SMILES Cc1ccc2c(c1)-c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C26H30O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4-6,10-11,16-18,27H,7-9,12-14H2,1-3H3
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62n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432717
PNG
(CHEMBL2348474)
Show SMILES Cc1ccc2c(c1)-c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C26H30O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4-6,10-11,16-18,27H,7-9,12-14H2,1-3H3
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64n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432721
PNG
(CHEMBL2348468)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20+,21+,26?/m0/s1
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65n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432724
PNG
(CHEMBL2348465)
Show SMILES CO\C=C/[C@@H]1CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,THB:26:25:22:28.27.29,26:27:24.25.30:22,29:27:24:30.21.22,29:21:24:28.26.27|
Show InChI InChI=1S/C28H38O3/c1-27(2)23-5-4-17(6-7-30-3)11-22(23)26-24(29)12-21(13-25(26)31-27)28-14-18-8-19(15-28)10-20(9-18)16-28/h6-7,12-13,17-20,22-23,29H,4-5,8-11,14-16H2,1-3H3/b7-6-/t17-,18?,19?,20?,22+,23+,28?/m0/s1
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67n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432725
PNG
(CHEMBL2348464)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC#N)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H35NO2/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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87n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432715
PNG
(CHEMBL2348476)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(O)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H28O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h3-4,8-10,14-16,26-27H,5-7,11-13H2,1-2H3
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89n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432724
PNG
(CHEMBL2348465)
Show SMILES CO\C=C/[C@@H]1CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,THB:26:25:22:28.27.29,26:27:24.25.30:22,29:27:24:30.21.22,29:21:24:28.26.27|
Show InChI InChI=1S/C28H38O3/c1-27(2)23-5-4-17(6-7-30-3)11-22(23)26-24(29)12-21(13-25(26)31-27)28-14-18-8-19(15-28)10-20(9-18)16-28/h6-7,12-13,17-20,22-23,29H,4-5,8-11,14-16H2,1-3H3/b7-6-/t17-,18?,19?,20?,22+,23+,28?/m0/s1
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90n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432725
PNG
(CHEMBL2348464)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CC#N)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H35NO2/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,29H,3-5,7-10,13-15H2,1-2H3/t16-,17?,18?,19?,21+,22+,27?/m0/s1
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100n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432721
PNG
(CHEMBL2348468)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20+,21+,26?/m0/s1
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121n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432718
PNG
(CHEMBL2348471)
Show SMILES CC(C)(C)C(=O)OCC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,t:8,THB:30:29:26:32.31.33,30:31:28.29.34:26,33:31:28:34.25.26,33:25:28:32.30.31|
Show InChI InChI=1S/C31H42O4/c1-29(2,3)28(33)34-17-18-6-7-24-23(11-18)27-25(32)12-22(13-26(27)35-30(24,4)5)31-14-19-8-20(15-31)10-21(9-19)16-31/h6,12-13,19-21,23-24,32H,7-11,14-17H2,1-5H3/t19?,20?,21?,23-,24-,31?/m1/s1
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126n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432727
PNG
(CHEMBL2346682)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H34O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,18-20,26-27H,3-7,10-13H2,1-2H3/t14?,15?,16?,18-,19+,20+,25?/m0/s1
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146n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432731
PNG
(CHEMBL2348458)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H32O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,19-20,27H,3-7,10-13H2,1-2H3/t14?,15?,16?,19-,20-,25?/m1/s1
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176n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432726
PNG
(CHEMBL2348463)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CI)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H35IO2/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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241n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432731
PNG
(CHEMBL2348458)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H32O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,19-20,27H,3-7,10-13H2,1-2H3/t14?,15?,16?,19-,20-,25?/m1/s1
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250n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432715
PNG
(CHEMBL2348476)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(O)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H28O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h3-4,8-10,14-16,26-27H,5-7,11-13H2,1-2H3
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251n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432727
PNG
(CHEMBL2346682)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H34O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,18-20,26-27H,3-7,10-13H2,1-2H3/t14?,15?,16?,18-,19+,20+,25?/m0/s1
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255n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432726
PNG
(CHEMBL2348463)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CI)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H35IO2/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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262n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432731
PNG
(CHEMBL2348458)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(=O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H32O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,19-20,27H,3-7,10-13H2,1-2H3/t14?,15?,16?,19-,20-,25?/m1/s1
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338n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432716
PNG
(CHEMBL2348475)
Show SMILES COc1ccc2c(c1)-c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-5-4-19(28-3)11-20(21)24-22(27)9-18(10-23(24)29-25)26-12-15-6-16(13-26)8-17(7-15)14-26/h4-5,9-11,15-17,27H,6-8,12-14H2,1-3H3
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338n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432726
PNG
(CHEMBL2348463)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CI)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H35IO2/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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346n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432719
PNG
(CHEMBL2348470)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](CCO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:25:24:21:27.26.28,25:26:23.24.29:21,28:26:23:29.20.21,28:20:23:27.25.26|
Show InChI InChI=1S/C27H38O3/c1-26(2)22-4-3-16(5-6-28)10-21(22)25-23(29)11-20(12-24(25)30-26)27-13-17-7-18(14-27)9-19(8-17)15-27/h11-12,16-19,21-22,28-29H,3-10,13-15H2,1-2H3/t16-,17?,18?,19?,21-,22-,27?/m1/s1
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365n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50432716
PNG
(CHEMBL2348475)
Show SMILES COc1ccc2c(c1)-c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-5-4-19(28-3)11-20(21)24-22(27)9-18(10-23(24)29-25)26-12-15-6-16(13-26)8-17(7-15)14-26/h4-5,9-11,15-17,27H,6-8,12-14H2,1-3H3
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507n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from rat CB1 receptor expressed in rat brain membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432715
PNG
(CHEMBL2348476)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(O)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H28O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h3-4,8-10,14-16,26-27H,5-7,11-13H2,1-2H3
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551n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50432727
PNG
(CHEMBL2346682)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@@H](O)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:23:22:19:25.24.26,23:24:21.22.27:19,26:24:21:27.18.19,26:18:21:25.23.24|
Show InChI InChI=1S/C25H34O3/c1-24(2)20-4-3-18(26)10-19(20)23-21(27)8-17(9-22(23)28-24)25-11-14-5-15(12-25)7-16(6-14)13-25/h8-9,14-16,18-20,26-27H,3-7,10-13H2,1-2H3/t14?,15?,16?,18-,19+,20+,25?/m0/s1
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672n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK293 cell membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50432716
PNG
(CHEMBL2348475)
Show SMILES COc1ccc2c(c1)-c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-5-4-19(28-3)11-20(21)24-22(27)9-18(10-23(24)29-25)26-12-15-6-16(13-26)8-17(7-15)14-26/h4-5,9-11,15-17,27H,6-8,12-14H2,1-3H3
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950n/an/an/an/an/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from mouse CB2 receptor expressed in mouse spleen membrane by competitive binding assay


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50432713
PNG
(CHEMBL2348472)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2CC(CO)=CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,c:16,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H34O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3,9-10,16-18,20-21,27-28H,4-8,11-14H2,1-2H3/t16?,17?,18?,20-,21-,26?/m1/s1
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n/an/an/an/a 230n/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50432712
PNG
(AM4089 | CHEMBL2348473)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(CO)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3-4,8-10,16-18,27-28H,5-7,11-14H2,1-2H3
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n/an/an/an/a 8n/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Partial agonist activity at human CB1 receptor transfected in HEK293 cells assessed as reduction in forskolin-stimulated cAMP accumulation after 30 m...


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21281
PNG
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r|
Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1
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n/an/an/an/a 1.76E+3n/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50432714
PNG
(AM4054 | CHEMBL2348462)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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n/an/an/an/a 1.30n/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor transfected in HEK293 cells assessed as reduction in forskolin-stimulated cAMP accumulation after 30 mins


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50169951
PNG
((6aR,10aR)-3-Adamantan-1-yl-6,6,9-trimethyl-6a,7,1...)
Show SMILES CC1=CC[C@@H]2[C@@H](C1)c1c(O)cc(cc1OC2(C)C)C12CC3CC(CC(C3)C1)C2 |r,t:1,TLB:11:18:21.20.25:23,THB:19:20:23:27.18.26,19:18:21.20.25:23,11:18:21:25.24.23,26:18:21:25.24.23,26:24:21:27.19.18|
Show InChI InChI=1S/C26H34O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4,10-11,16-18,20-21,27H,5-9,12-14H2,1-3H3/t16?,17?,18?,20-,21-,26?/m1/s1
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n/an/an/an/a 1.53E+3n/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50432714
PNG
(AM4054 | CHEMBL2348462)
Show SMILES CC1(C)Oc2cc(cc(O)c2[C@@H]2C[C@H](CO)CC[C@@H]12)C12CC3CC(CC(C3)C1)C2 |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H36O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h9-10,15-18,20-21,27-28H,3-8,11-14H2,1-2H3/t15-,16?,17?,18?,20-,21-,26?/m1/s1
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n/an/an/an/a 96n/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50432712
PNG
(AM4089 | CHEMBL2348473)
Show SMILES CC1(C)Oc2cc(cc(O)c2-c2cc(CO)ccc12)C12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25|
Show InChI InChI=1S/C26H30O3/c1-25(2)21-4-3-15(14-27)8-20(21)24-22(28)9-19(10-23(24)29-25)26-11-16-5-17(12-26)7-18(6-16)13-26/h3-4,8-10,16-18,27-28H,5-7,11-14H2,1-2H3
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n/an/an/an/a 450n/an/an/an/a



Northeastern University

Curated by ChEMBL


Assay Description
Agonist activity at human CB1 receptor transfected in human U2OS cells assessed as beta-arrestin2-GFP aggregation after 40 mins


J Med Chem 56: 3904-21 (2013)


Article DOI: 10.1021/jm4000775
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%