Affinity Data by PubMed id=23627282

PubMed code 23627282

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50439673 (CHEMBL2417782) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of His-6-tagged full length HDAC3 (unknown origin) expressed in sf9 cells and co-expressed in SMRT gene (395 to 489) using carboxyfluoresc...				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50439674 (RICOLINOSTAT \| US10858323, Compound 2 \| US11207431...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) using fluorophore tripeptide as substrate after 30 mins				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50261816 (CHEMBL511749 \| tert-butyl 4-(3-((7-(hydroxyamino)-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) using carboxyfluorescein (FAM)-labeled acetylated peptide as substrate after 17 hrs by fluorescence-based electr...				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM22449 (CHEMBL356769 \| N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3/NcoR2 (unknown origin) using RHKKAc from p53 as substrate				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50161470 (6-(2-Mercapto-acetylamino)-hexanoic acid quinolin-...) Show SMILES SCC(=O)NCCCCCC(=O)Nc1cccc2cccnc12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin)				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50214437 (6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyam...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin)				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50439672 (CHEMBL2417783) Show SMILES Cc1onc(c1C(=O)NCCCCCNC(=O)CS)-c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin)				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50439671 (CHEMBL2417784) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin)				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50380399 (CHEMBL2018302 \| Tubastatin A \| US10227295, Compoun...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3/NcoR2 (unknown origin) using RHKKAc from p53 as substrate				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50015144 (2-(4-Butoxy-phenyl)-N-hydroxy-acetamide \| Bufexama...) Show SMILES CCCCOc1ccc(CC(=O)NO)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	3.41E+5	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin)				J Med Chem 56: 6297-313 (2013) Article DOI: 10.1021/jm4001659 BindingDB Entry DOI: 10.7270/Q29G5P7J
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%