BindingDB logo
myBDB logout

PubMed code 23644197

Compile data set for download or QSAR
Found 51 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435583
PNG
(CHEMBL2393147)
Show SMILES OCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H25F2N7O4/c22-17(23)18-24-16-14(2-1-3-15(16)34-13-8-31)30(18)21-26-19(28-4-9-32-10-5-28)25-20(27-21)29-6-11-33-12-7-29/h1-3,17,31H,4-13H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435576
PNG
(CHEMBL2393134)
Show SMILES CN(C)CCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H32F2N8O3/c1-31(2)7-4-12-37-18-6-3-5-17-19(18)27-21(20(25)26)34(17)24-29-22(32-8-13-35-14-9-32)28-23(30-24)33-10-15-36-16-11-33/h3,5-6,20H,4,7-16H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.5n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435581
PNG
(CHEMBL2393143)
Show SMILES OCC(O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N7O5/c23-18(24)19-25-17-15(2-1-3-16(17)36-13-14(33)12-32)31(19)22-27-20(29-4-8-34-9-5-29)26-21(28-22)30-6-10-35-11-7-30/h1-3,14,18,32-33H,4-13H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.70n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435583
PNG
(CHEMBL2393147)
Show SMILES OCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H25F2N7O4/c22-17(23)18-24-16-14(2-1-3-15(16)34-13-8-31)30(18)21-26-19(28-4-9-32-10-5-28)25-20(27-21)29-6-11-33-12-7-29/h1-3,17,31H,4-13H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.30n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435573
PNG
(CHEMBL2393137)
Show SMILES OC(COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)CN1CCOCC1
Show InChI InChI=1S/C26H34F2N8O5/c27-22(28)23-29-21-19(2-1-3-20(21)41-17-18(37)16-33-4-10-38-11-5-33)36(23)26-31-24(34-6-12-39-13-7-34)30-25(32-26)35-8-14-40-15-9-35/h1-3,18,22,37H,4-17H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.5n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435576
PNG
(CHEMBL2393134)
Show SMILES CN(C)CCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H32F2N8O3/c1-31(2)7-4-12-37-18-6-3-5-17-19(18)27-21(20(25)26)34(17)24-29-22(32-8-13-35-14-9-32)28-23(30-24)33-10-15-36-16-11-33/h3,5-6,20H,4,7-16H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.30n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435582
PNG
(CHEMBL2393148)
Show SMILES OCCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N7O4/c23-18(24)19-25-17-15(3-1-4-16(17)35-10-2-9-32)31(19)22-27-20(29-5-11-33-12-6-29)26-21(28-22)30-7-13-34-14-8-30/h1,3-4,18,32H,2,5-14H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435576
PNG
(CHEMBL2393134)
Show SMILES CN(C)CCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H32F2N8O3/c1-31(2)7-4-12-37-18-6-3-5-17-19(18)27-21(20(25)26)34(17)24-29-22(32-8-13-35-14-9-32)28-23(30-24)33-10-15-36-16-11-33/h3,5-6,20H,4,7-16H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435581
PNG
(CHEMBL2393143)
Show SMILES OCC(O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N7O5/c23-18(24)19-25-17-15(2-1-3-16(17)36-13-14(33)12-32)31(19)22-27-20(29-4-8-34-9-5-29)26-21(28-22)30-6-10-35-11-7-30/h1-3,14,18,32-33H,4-13H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 12n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435574
PNG
(CHEMBL2393136)
Show SMILES CN(C)CC(O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H32F2N8O4/c1-31(2)14-16(35)15-38-18-5-3-4-17-19(18)27-21(20(25)26)34(17)24-29-22(32-6-10-36-11-7-32)28-23(30-24)33-8-12-37-13-9-33/h3-5,16,20,35H,6-15H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435572
PNG
(CHEMBL2393138)
Show SMILES CN(C)CCNc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H31F2N9O2/c1-31(2)7-6-26-16-4-3-5-17-18(16)27-20(19(24)25)34(17)23-29-21(32-8-12-35-13-9-32)28-22(30-23)33-10-14-36-15-11-33/h3-5,19,26H,6-15H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435583
PNG
(CHEMBL2393147)
Show SMILES OCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H25F2N7O4/c22-17(23)18-24-16-14(2-1-3-15(16)34-13-8-31)30(18)21-26-19(28-4-9-32-10-5-28)25-20(27-21)29-6-11-33-12-7-29/h1-3,17,31H,4-13H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435580
PNG
(CHEMBL2393144)
Show SMILES NCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H26F2N8O3/c22-17(23)18-25-16-14(2-1-3-15(16)34-9-4-24)31(18)21-27-19(29-5-10-32-11-6-29)26-20(28-21)30-7-12-33-13-8-30/h1-3,17H,4-13,24H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435575
PNG
(CHEMBL2393135)
Show SMILES FC(F)c1nc2c(OCCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C26H34F2N8O4/c27-22(28)23-29-21-19(3-1-4-20(21)40-12-2-5-33-6-13-37-14-7-33)36(23)26-31-24(34-8-15-38-16-9-34)30-25(32-26)35-10-17-39-18-11-35/h1,3-4,22H,2,5-18H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435579
PNG
(CHEMBL2393145)
Show SMILES CN(C)CCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H30F2N8O3/c1-30(2)6-15-36-17-5-3-4-16-18(17)26-20(19(24)25)33(16)23-28-21(31-7-11-34-12-8-31)27-22(29-23)32-9-13-35-14-10-32/h3-5,19H,6-15H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 19n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435580
PNG
(CHEMBL2393144)
Show SMILES NCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H26F2N8O3/c22-17(23)18-25-16-14(2-1-3-15(16)34-9-4-24)31(18)21-27-19(29-5-10-32-11-6-29)26-20(28-21)30-7-12-33-13-8-30/h1-3,17H,4-13,24H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435582
PNG
(CHEMBL2393148)
Show SMILES OCCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N7O4/c23-18(24)19-25-17-15(3-1-4-16(17)35-10-2-9-32)31(19)22-27-20(29-5-11-33-12-6-29)26-21(28-22)30-7-13-34-14-8-30/h1,3-4,18,32H,2,5-14H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435581
PNG
(CHEMBL2393143)
Show SMILES OCC(O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N7O5/c23-18(24)19-25-17-15(2-1-3-16(17)36-13-14(33)12-32)31(19)22-27-20(29-4-8-34-9-5-29)26-21(28-22)30-6-10-35-11-7-30/h1-3,14,18,32-33H,4-13H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435577
PNG
(CHEMBL2393133)
Show SMILES NCCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H28F2N8O3/c23-18(24)19-26-17-15(3-1-4-16(17)35-10-2-5-25)32(19)22-28-20(30-6-11-33-12-7-30)27-21(29-22)31-8-13-34-14-9-31/h1,3-4,18H,2,5-14,25H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 28n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435577
PNG
(CHEMBL2393133)
Show SMILES NCCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H28F2N8O3/c23-18(24)19-26-17-15(3-1-4-16(17)35-10-2-5-25)32(19)22-28-20(30-6-11-33-12-7-30)27-21(29-22)31-8-13-34-14-9-31/h1,3-4,18H,2,5-14,25H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 28n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435575
PNG
(CHEMBL2393135)
Show SMILES FC(F)c1nc2c(OCCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C26H34F2N8O4/c27-22(28)23-29-21-19(3-1-4-20(21)40-12-2-5-33-6-13-37-14-7-33)36(23)26-31-24(34-8-15-38-16-9-34)30-25(32-26)35-10-17-39-18-11-35/h1,3-4,22H,2,5-18H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 29n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435574
PNG
(CHEMBL2393136)
Show SMILES CN(C)CC(O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H32F2N8O4/c1-31(2)14-16(35)15-38-18-5-3-4-17-19(18)27-21(20(25)26)34(17)24-29-22(32-6-10-36-11-7-32)28-23(30-24)33-8-12-37-13-9-33/h3-5,16,20,35H,6-15H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435574
PNG
(CHEMBL2393136)
Show SMILES CN(C)CC(O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H32F2N8O4/c1-31(2)14-16(35)15-38-18-5-3-4-17-19(18)27-21(20(25)26)34(17)24-29-22(32-6-10-36-11-7-32)28-23(30-24)33-8-12-37-13-9-33/h3-5,16,20,35H,6-15H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 33n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435579
PNG
(CHEMBL2393145)
Show SMILES CN(C)CCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H30F2N8O3/c1-30(2)6-15-36-17-5-3-4-16-18(17)26-20(19(24)25)33(16)23-28-21(31-7-11-34-12-8-31)27-22(29-23)32-9-13-35-14-10-32/h3-5,19H,6-15H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 35n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435584
PNG
(CHEMBL2393146)
Show SMILES OC(=O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H23F2N7O5/c22-17(23)18-24-16-13(2-1-3-14(16)35-12-15(31)32)30(18)21-26-19(28-4-8-33-9-5-28)25-20(27-21)29-6-10-34-11-7-29/h1-3,17H,4-12H2,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 39n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435573
PNG
(CHEMBL2393137)
Show SMILES OC(COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)CN1CCOCC1
Show InChI InChI=1S/C26H34F2N8O5/c27-22(28)23-29-21-19(2-1-3-20(21)41-17-18(37)16-33-4-10-38-11-5-33)36(23)26-31-24(34-6-12-39-13-7-34)30-25(32-26)35-8-14-40-15-9-35/h1-3,18,22,37H,4-17H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 41n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435571
PNG
(CHEMBL2393139)
Show SMILES NCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H25F2N9O3/c22-17(23)18-26-16-13(25-15(33)12-24)2-1-3-14(16)32(18)21-28-19(30-4-8-34-9-5-30)27-20(29-21)31-6-10-35-11-7-31/h1-3,17H,4-12,24H2,(H,25,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 52n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435584
PNG
(CHEMBL2393146)
Show SMILES OC(=O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H23F2N7O5/c22-17(23)18-24-16-13(2-1-3-14(16)35-12-15(31)32)30(18)21-26-19(28-4-8-33-9-5-28)25-20(27-21)29-6-10-34-11-7-29/h1-3,17H,4-12H2,(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 52n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435578
PNG
(CHEMBL2393132)
Show SMILES FC(F)c1nc2c(OCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C25H32F2N8O4/c26-21(27)22-28-20-18(2-1-3-19(20)39-17-6-32-4-11-36-12-5-32)35(22)25-30-23(33-7-13-37-14-8-33)29-24(31-25)34-9-15-38-16-10-34/h1-3,21H,4-17H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 53n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435573
PNG
(CHEMBL2393137)
Show SMILES OC(COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)CN1CCOCC1
Show InChI InChI=1S/C26H34F2N8O5/c27-22(28)23-29-21-19(2-1-3-20(21)41-17-18(37)16-33-4-10-38-11-5-33)36(23)26-31-24(34-6-12-39-13-7-34)30-25(32-26)35-8-14-40-15-9-35/h1-3,18,22,37H,4-17H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 53n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435572
PNG
(CHEMBL2393138)
Show SMILES CN(C)CCNc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H31F2N9O2/c1-31(2)7-6-26-16-4-3-5-17-18(16)27-20(19(24)25)34(17)23-29-21(32-8-12-35-13-9-32)28-22(30-23)33-10-14-36-15-11-33/h3-5,19,26H,6-15H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 73n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435577
PNG
(CHEMBL2393133)
Show SMILES NCCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H28F2N8O3/c23-18(24)19-26-17-15(3-1-4-16(17)35-10-2-5-25)32(19)22-28-20(30-6-11-33-12-7-30)27-21(29-22)31-8-13-34-14-9-31/h1,3-4,18H,2,5-14,25H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 75n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435575
PNG
(CHEMBL2393135)
Show SMILES FC(F)c1nc2c(OCCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C26H34F2N8O4/c27-22(28)23-29-21-19(3-1-4-20(21)40-12-2-5-33-6-13-37-14-7-33)36(23)26-31-24(34-8-15-38-16-9-34)30-25(32-26)35-10-17-39-18-11-35/h1,3-4,22H,2,5-18H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 76n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435570
PNG
(CHEMBL2393140)
Show SMILES CN(C)CC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H29F2N9O3/c1-31(2)14-17(35)26-15-4-3-5-16-18(15)27-20(19(24)25)34(16)23-29-21(32-6-10-36-11-7-32)28-22(30-23)33-8-12-37-13-9-33/h3-5,19H,6-14H2,1-2H3,(H,26,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 99n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435579
PNG
(CHEMBL2393145)
Show SMILES CN(C)CCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H30F2N8O3/c1-30(2)6-15-36-17-5-3-4-16-18(17)26-20(19(24)25)33(16)23-28-21(31-7-11-34-12-8-31)27-22(29-23)32-9-13-35-14-10-32/h3-5,19H,6-15H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 105n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435568
PNG
(CHEMBL2393142)
Show SMILES CN(C)CCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H31F2N9O3/c1-32(2)7-6-18(36)27-16-4-3-5-17-19(16)28-21(20(25)26)35(17)24-30-22(33-8-12-37-13-9-33)29-23(31-24)34-10-14-38-15-11-34/h3-5,20H,6-15H2,1-2H3,(H,27,36)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 112n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435571
PNG
(CHEMBL2393139)
Show SMILES NCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H25F2N9O3/c22-17(23)18-26-16-13(25-15(33)12-24)2-1-3-14(16)32(18)21-28-19(30-4-8-34-9-5-30)27-20(29-21)31-6-10-35-11-7-31/h1-3,17H,4-12,24H2,(H,25,33)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 119n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435580
PNG
(CHEMBL2393144)
Show SMILES NCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H26F2N8O3/c22-17(23)18-25-16-14(2-1-3-15(16)34-9-4-24)31(18)21-27-19(29-5-10-32-11-6-29)26-20(28-21)30-7-12-33-13-8-30/h1-3,17H,4-13,24H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435578
PNG
(CHEMBL2393132)
Show SMILES FC(F)c1nc2c(OCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C25H32F2N8O4/c26-21(27)22-28-20-18(2-1-3-19(20)39-17-6-32-4-11-36-12-5-32)35(22)25-30-23(33-7-13-37-14-8-33)29-24(31-25)34-9-15-38-16-10-34/h1-3,21H,4-17H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435578
PNG
(CHEMBL2393132)
Show SMILES FC(F)c1nc2c(OCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C25H32F2N8O4/c26-21(27)22-28-20-18(2-1-3-19(20)39-17-6-32-4-11-36-12-5-32)35(22)25-30-23(33-7-13-37-14-8-33)29-24(31-25)34-9-15-38-16-10-34/h1-3,21H,4-17H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435582
PNG
(CHEMBL2393148)
Show SMILES OCCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N7O4/c23-18(24)19-25-17-15(3-1-4-16(17)35-10-2-9-32)31(19)22-27-20(29-5-11-33-12-6-29)26-21(28-22)30-7-13-34-14-8-30/h1,3-4,18,32H,2,5-14H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 170n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435572
PNG
(CHEMBL2393138)
Show SMILES CN(C)CCNc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H31F2N9O2/c1-31(2)7-6-26-16-4-3-5-17-18(16)27-20(19(24)25)34(17)23-29-21(32-8-12-35-13-9-32)28-22(30-23)33-10-14-36-15-11-33/h3-5,19,26H,6-15H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 174n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50435569
PNG
(CHEMBL2393141)
Show SMILES NCCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N9O3/c23-18(24)19-27-17-14(26-16(34)4-5-25)2-1-3-15(17)33(19)22-29-20(31-6-10-35-11-7-31)28-21(30-22)32-8-12-36-13-9-32/h1-3,18H,4-13,25H2,(H,26,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 210n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435584
PNG
(CHEMBL2393146)
Show SMILES OC(=O)COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H23F2N7O5/c22-17(23)18-24-16-13(2-1-3-14(16)35-12-15(31)32)30(18)21-26-19(28-4-8-33-9-5-28)25-20(27-21)29-6-10-34-11-7-29/h1-3,17H,4-12H2,(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 274n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435570
PNG
(CHEMBL2393140)
Show SMILES CN(C)CC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H29F2N9O3/c1-31(2)14-17(35)26-15-4-3-5-16-18(15)27-20(19(24)25)34(16)23-29-21(32-6-10-36-11-7-32)28-22(30-23)33-8-12-37-13-9-33/h3-5,19H,6-14H2,1-2H3,(H,26,35)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 379n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435568
PNG
(CHEMBL2393142)
Show SMILES CN(C)CCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H31F2N9O3/c1-32(2)7-6-18(36)27-16-4-3-5-17-19(16)28-21(20(25)26)35(17)24-30-22(33-8-12-37-13-9-33)29-23(31-24)34-10-14-38-15-11-34/h3-5,20H,6-15H2,1-2H3,(H,27,36)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 486n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435571
PNG
(CHEMBL2393139)
Show SMILES NCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C21H25F2N9O3/c22-17(23)18-26-16-13(25-15(33)12-24)2-1-3-14(16)32(18)21-28-19(30-4-8-34-9-5-30)27-20(29-21)31-6-10-35-11-7-31/h1-3,17H,4-12,24H2,(H,25,33)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 740n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM50435569
PNG
(CHEMBL2393141)
Show SMILES NCCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N9O3/c23-18(24)19-27-17-14(26-16(34)4-5-25)2-1-3-15(17)33(19)22-29-20(31-6-10-35-11-7-31)28-21(30-22)32-8-12-36-13-9-32/h1-3,18H,4-13,25H2,(H,26,34)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 855n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435570
PNG
(CHEMBL2393140)
Show SMILES CN(C)CC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C23H29F2N9O3/c1-31(2)14-17(35)26-15-4-3-5-16-18(15)27-20(19(24)25)34(16)23-29-21(32-6-10-36-11-7-32)28-22(30-23)33-8-12-37-13-9-33/h3-5,19H,6-14H2,1-2H3,(H,26,35)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.04E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435568
PNG
(CHEMBL2393142)
Show SMILES CN(C)CCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C24H31F2N9O3/c1-32(2)7-6-18(36)27-16-4-3-5-17-19(16)28-21(20(25)26)35(17)24-30-22(33-8-12-37-13-9-33)29-23(31-24)34-10-14-38-15-11-34/h3-5,20H,6-15H2,1-2H3,(H,27,36)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50435569
PNG
(CHEMBL2393141)
Show SMILES NCCC(=O)Nc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Show InChI InChI=1S/C22H27F2N9O3/c23-18(24)19-27-17-14(26-16(34)4-5-25)2-1-3-15(17)33(19)22-29-20(31-6-10-35-11-7-31)28-21(30-22)32-8-12-36-13-9-32/h1-3,18H,4-13,25H2,(H,26,34)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.02E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...


Eur J Med Chem 64: 137-47 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.038
BindingDB Entry DOI: 10.7270/Q2377B33
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%