Affinity Data by PubMed id=23684893

PubMed code 23684893

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50436151 (CHEMBL2398212) Show SMILES Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50436152 (SPONGIACIDIN C) Show SMILES O=C1NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 21 (Homo sapiens (Human))	BDBM50436152 (SPONGIACIDIN C) Show SMILES O=C1NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of core catalytic domain of USP21 (unknown origin) using ubiquitin-Rh110 as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50436149 (CHEMBL2398214) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM50436150 (CHEMBL2398213) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 2 (Homo sapiens (Human))	BDBM50436152 (SPONGIACIDIN C) Show SMILES O=C1NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of core catalytic domain of USP2 (unknown origin) using diubiquitin IQF K4804 as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50436152 (SPONGIACIDIN C) Show SMILES O=C1NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of core catalytic domain of SENP1 (unknown origin) using SUMO3-EKL as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50436152 (SPONGIACIDIN C) Show SMILES O=C1NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of core catalytic domain of USP8 (unknown origin) using ubiquitin-Rh110 as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
Kumamoto University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%