Affinity Data by PubMed id=23769640

PubMed code 23769640

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase (Vibrio cholerae)	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Flaveria bidentis recombinant CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26990 (CHEMBL1644699 \| HS anion \| HS(-1) \| hydrogen(sulfi...) Show SMILES [SH-] Show InChI InChI=1S/H2S/h1H2/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents	Article PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM60995 (BDBM50401535 \| CNO- \| fulminate ion) Show SMILES [O-][N+]#[C-] Show InChI InChI=1S/CNO/c1-2-3/q-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26984 (CHEMBL1644697 \| CN(-1) \| cyanide \| iminomethanide) Show SMILES [C-]#N Show InChI InChI=1S/CN/c1-2/q-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26985 (2-triaza-1,2-diyne \| CHEMBL79455 \| CHEMBL89295 \| N...) Show SMILES [N-]=[N+]=[N-] Show InChI InChI=1S/N3/c1-3-2/q-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26987 (CHEMBL180485 \| CO3(2-) \| SODIUM CARBONATE \| carbon...) Show SMILES [O-]C([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26989 (CHEMBL93268 \| NO2- \| nitrite \| nitrite ion) Show SMILES [O-]N=O Show InChI InChI=1S/HNO2/c2-1-3/h(H,2,3)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.80E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26983 (CHEMBL1644028 \| SCN(-1) \| Thiocyanate \| cyanosulfa...) Show SMILES [N-]=C=S Show InChI InChI=1S/CNS/c2-1-3/q-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26991 (CHEMBL1689285 \| HSO3- \| bisulfite \| hydrogen sulfi...) Show SMILES OS([O-])=O Show InChI InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.17E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26988 (CHEMBL1644029 \| CHEMBL1644698 \| CHEMBL186200 \| NO3...) Show SMILES [O-][N+]([O-])=O Show InChI InChI=1S/NO3/c2-1(3)4/q-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.65E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26986 (CHEMBL363707 \| HCO3- \| SODIUM BICARBONATE \| bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26980 (Br- \| CHEMBL1644030 \| CHEMBL1644694 \| bromide \| br...) Show SMILES [Br-] Show InChI InChI=1S/BrH/h1H/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	6.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26981 (CHEMBL1644695 \| I- \| POTASSIUM IODIDE \| iodide \| i...) Show SMILES [I-] Show InChI InChI=1S/HI/h1H/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	1.60E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26992 (CHEMBL183495 \| SO4(2-) \| SODIUM SULFATE \| sulfate ...) Show SMILES [O-]S([O-])(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	>2.00E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26979 (CHEMBL69710 \| Cl- \| POTASSIUM CHLORIDE \| SODIUM CH...) Show SMILES [Cl-] Show InChI InChI=1S/ClH/h1H/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	>2.00E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair
Carbonic anhydrase (Methanosarcina thermophila)	BDBM26978 (BDBM50098540 \| CHEMBL1528 \| CHEMBL1644027 \| F- \| f...) Show SMILES [F-] Show InChI InChI=1S/FH/h1H/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	>2.00E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay				Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%