Affinity Data by PubMed id=23994869

PubMed code 23994869

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM23419 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin) using dibenzylfluorscein as substrate incubated with NADP+ for 10 mins prior to substrate addition measured ...				Eur J Med Chem 68: 412-21 (2013) Article DOI: 10.1016/j.ejmech.2013.07.052 BindingDB Entry DOI: 10.7270/Q2765GSV
Universit£ di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50441056 (CHEMBL2430196) Show SMILES Oc1ccc(O)c(c1)-c1cn2ccsc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin) using dibenzylfluorscein as substrate incubated with NADP+ for 10 mins prior to substrate addition measured ...				Eur J Med Chem 68: 412-21 (2013) Article DOI: 10.1016/j.ejmech.2013.07.052 BindingDB Entry DOI: 10.7270/Q2765GSV
Universit£ di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50441057 (CHEMBL2430197) Show SMILES Cc1cn2cc(nc2s1)-c1ccc(O)c(O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin) using dibenzylfluorscein as substrate incubated with NADP+ for 10 mins prior to substrate addition measured ...				Eur J Med Chem 68: 412-21 (2013) Article DOI: 10.1016/j.ejmech.2013.07.052 BindingDB Entry DOI: 10.7270/Q2765GSV
Universit£ di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50441056 (CHEMBL2430196) Show SMILES Oc1ccc(O)c(c1)-c1cn2ccsc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of iNOS-mediated NO production in mouse RAW264.7 cells by Griess assay				Eur J Med Chem 68: 412-21 (2013) Article DOI: 10.1016/j.ejmech.2013.07.052 BindingDB Entry DOI: 10.7270/Q2765GSV
Universit£ di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50441057 (CHEMBL2430197) Show SMILES Cc1cn2cc(nc2s1)-c1ccc(O)c(O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of iNOS-mediated NO production in mouse RAW264.7 cells by Griess assay				Eur J Med Chem 68: 412-21 (2013) Article DOI: 10.1016/j.ejmech.2013.07.052 BindingDB Entry DOI: 10.7270/Q2765GSV
Universit£ di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50441055 (CHEMBL1744478) Show SMILES CNC(=N)NCCC[C@H](N)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of iNOS-mediated NO production in mouse RAW264.7 cells by Griess assay				Eur J Med Chem 68: 412-21 (2013) Article DOI: 10.1016/j.ejmech.2013.07.052 BindingDB Entry DOI: 10.7270/Q2765GSV
Universit£ di Bologna Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%