Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-acetyltransferase domain-containing protein (Pseudomonas aeruginosa) | BDBM50335563 ((6R,7R)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-(...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 4.93E+4 | n/a | n/a | n/a | 7.5 | 25 |
University of Virginia | Assay Description Isothermal titration calorimetry (ITC) measurements were performed at 25 °C using an iTC200 calorimeter (MicroCal). Preparations of purified pr... | J Biol Chem 288: 30223-35 (2013) Article DOI: 10.1074/jbc.M113.501353 BindingDB Entry DOI: 10.7270/Q22N514W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
N-acetyltransferase domain-containing protein (Pseudomonas aeruginosa) | BDBM213238 (AcCoA) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | 7.5 | 25 |
University of Virginia | Assay Description Isothermal titration calorimetry (ITC) measurements were performed at 25 °C using an iTC200 calorimeter (MicroCal). Preparations of purified pr... | J Biol Chem 288: 30223-35 (2013) Article DOI: 10.1074/jbc.M113.501353 BindingDB Entry DOI: 10.7270/Q22N514W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acetyltransferase domain-containing protein (Pseudomonas aeruginosa) | BDBM213239 (CoA) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | 7.5 | 25 |
University of Virginia | Assay Description Isothermal titration calorimetry (ITC) measurements were performed at 25 °C using an iTC200 calorimeter (MicroCal). Preparations of purified pr... | J Biol Chem 288: 30223-35 (2013) Article DOI: 10.1074/jbc.M113.501353 BindingDB Entry DOI: 10.7270/Q22N514W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acetyltransferase domain-containing protein (Pseudomonas aeruginosa) | BDBM50335523 ((6R,7R)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-y...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | 7.5 | 25 |
University of Virginia | Assay Description Isothermal titration calorimetry (ITC) measurements were performed at 25 °C using an iTC200 calorimeter (MicroCal). Preparations of purified pr... | J Biol Chem 288: 30223-35 (2013) Article DOI: 10.1074/jbc.M113.501353 BindingDB Entry DOI: 10.7270/Q22N514W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acetyltransferase domain-containing protein (Pseudomonas aeruginosa) | BDBM82898 ((6R,7R)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.69E+4 | n/a | n/a | n/a | 7.5 | 25 |
University of Virginia | Assay Description Isothermal titration calorimetry (ITC) measurements were performed at 25 °C using an iTC200 calorimeter (MicroCal). Preparations of purified pr... | J Biol Chem 288: 30223-35 (2013) Article DOI: 10.1074/jbc.M113.501353 BindingDB Entry DOI: 10.7270/Q22N514W | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
N-acetyltransferase domain-containing protein (Pseudomonas aeruginosa) | BDBM50350472 (640/359 | Anaptivan | CEFUROXIME | Ceftin) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.77E+5 | n/a | n/a | n/a | 7.5 | 25 |
University of Virginia | Assay Description Isothermal titration calorimetry (ITC) measurements were performed at 25 °C using an iTC200 calorimeter (MicroCal). Preparations of purified pr... | J Biol Chem 288: 30223-35 (2013) Article DOI: 10.1074/jbc.M113.501353 BindingDB Entry DOI: 10.7270/Q22N514W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acetyltransferase domain-containing protein (Pseudomonas aeruginosa) | BDBM213237 (4-Methylumbelliferyl phosphate) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.65E+5 | n/a | n/a | n/a | 7.5 | 25 |
University of Virginia | Assay Description Isothermal titration calorimetry (ITC) measurements were performed at 25 °C using an iTC200 calorimeter (MicroCal). Preparations of purified pr... | J Biol Chem 288: 30223-35 (2013) Article DOI: 10.1074/jbc.M113.501353 BindingDB Entry DOI: 10.7270/Q22N514W | |||||||||||
More data for this Ligand-Target Pair |