Affinity Data by PubMed id=24007511

PubMed code 24007511

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440477 (CHEMBL2426053) Show SMILES CN(CC#C)CC(O)COc1ccc2cc(Br)ccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440475 (CHEMBL2426048) Show SMILES OC(CNCC#C)COc1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440475 (CHEMBL2426048) Show SMILES OC(CNCC#C)COc1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440479 (CHEMBL2426051) Show SMILES CN(CC#C)CC(O)COc1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440478 (CHEMBL2426052) Show SMILES OC(CNCC#C)COc1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440480 (CHEMBL2426047) Show SMILES CN(CCCOc1cccc(NC(=O)c2ccccc2)c1)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440476 (CHEMBL2426134) Show SMILES OC(CNC1CC1)COc1ccc2cc(Br)ccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440482 (CHEMBL2426041) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440483 (CHEMBL2426040) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50440481 (CHEMBL2426046) Show SMILES O=C(Nc1cccc(OCCCNCC#C)c1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.84E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Freiburg Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin) expressed in Sf9 cells using H3K4(me2) as substrate preincubated for 30 mins prior to substrate addition measured...				J Med Chem 56: 7334-42 (2013) Article DOI: 10.1021/jm400792m BindingDB Entry DOI: 10.7270/Q2V40WN1
University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%