Affinity Data by PubMed id=24015910

PubMed code 24015910

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hexokinase-4 (Homo sapiens (Human))	BDBM50441148 (CHEMBL2430867) Show SMILES Cc1csc(Nc2ncccc2OCc2cccc3cccnc23)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441150 (CHEMBL2430865) Show SMILES Cc1csc(Nc2ncccc2OCc2cccnc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.78E+3	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441154 (CHEMBL2430862) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	119	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441157 (CHEMBL2430859) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	235	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441147 (CHEMBL2430851) Show SMILES Cc1csc(Nc2ncc(Br)cc2OCc2ccccc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	687	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441152 (CHEMBL2430868) Show SMILES Cc1csc(Nc2ncccc2OCc2ccccc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4.94E+3	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Hexokinase-4 (Homo sapiens (Human))	BDBM50441142 (CHEMBL2430856) Show SMILES Cc1csc(Nc2ncc(Cl)cc2OCc2ccccc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	796	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441155 (CHEMBL2430861) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	325	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441144 (CHEMBL2430854) Show SMILES CC(C)Cc1csc(Nc2ncc(Br)cc2OCc2ccccc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	356	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441153 (CHEMBL2430863) Show SMILES COc1cccc(COc2cccnc2Nc2nc(C)cs2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441140 (CHEMBL2430858) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	231	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441141 (CHEMBL2430857) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	208	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441146 (CHEMBL2430852) Show SMILES CCc1csc(Nc2ncc(Br)cc2OCc2ccccc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	562	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441156 (CHEMBL2430860) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	77	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441143 (CHEMBL2430855) Show SMILES Cc1csc(Nc2ncc(C)cc2OCc2ccccc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Hexokinase-4 (Homo sapiens (Human))	BDBM50441145 (CHEMBL2430853) Show SMILES CC(C)c1csc(Nc2ncc(Br)cc2OCc2ccccc2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441149 (CHEMBL2430866) Show SMILES Cc1csc(Nc2ncccc2OCc2cccc(O)c2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.44E+3	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50441151 (CHEMBL2430864) Show SMILES Cc1csc(Nc2ncccc2OCc2ccccn2)n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins				J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH
Array BioPharma Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%