Affinity Data by PubMed id=24177366

PubMed code 24177366

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50443421 (CHEMBL3087263) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Blood Transfusion Centre of Slovenia Curated by ChEMBL					Assay Description Antagonist activity at human TLR4 expressed in LPS-stimulated HEK293 cells co-expressing MDM2 and CD14 after 2 hrs by SEAP assay				Eur J Med Chem 70: 393-9 (2013) Article DOI: 10.1016/j.ejmech.2013.10.019 BindingDB Entry DOI: 10.7270/Q2HQ41CC
Blood Transfusion Centre of Slovenia Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50443420 (CHEMBL3087262) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Blood Transfusion Centre of Slovenia Curated by ChEMBL					Assay Description Antagonist activity at human TLR4 expressed in LPS-stimulated HEK293 cells co-expressing MDM2 and CD14 after 2 hrs by SEAP assay				Eur J Med Chem 70: 393-9 (2013) Article DOI: 10.1016/j.ejmech.2013.10.019 BindingDB Entry DOI: 10.7270/Q2HQ41CC
Blood Transfusion Centre of Slovenia Curated by ChEMBL					More data for this Ligand-Target Pair
Toll-like receptor 4 (Homo sapiens (Human))	BDBM50443419 (CHEMBL3087261) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
Blood Transfusion Centre of Slovenia Curated by ChEMBL					Assay Description Antagonist activity at human TLR4 expressed in LPS-stimulated HEK293 cells co-expressing MDM2 and CD14 after 2 hrs by SEAP assay				Eur J Med Chem 70: 393-9 (2013) Article DOI: 10.1016/j.ejmech.2013.10.019 BindingDB Entry DOI: 10.7270/Q2HQ41CC
Blood Transfusion Centre of Slovenia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%