Found 34 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445402
(CHEMBL3104658)Show InChI InChI=1S/C14H15N3OS/c1-2-5-11-14(18)17-13(19-11)8-12-15-9-6-3-4-7-10(9)16-12/h3-4,6-8,11H,2,5H2,1H3,(H,15,16)(H,17,18)/b13-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50431947
(CHEMBL2348091)Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445403
(CHEMBL3104666)Show SMILES CCCC1SC(NC1=O)=Cc1nc2ccc(F)cc2[nH]1 |w:9.10| Show InChI InChI=1S/C14H14FN3OS/c1-2-3-11-14(19)18-13(20-11)7-12-16-9-5-4-8(15)6-10(9)17-12/h4-7,11H,2-3H2,1H3,(H,16,17)(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445410
(CHEMBL3104659)Show InChI InChI=1S/C15H17N3OS/c1-2-3-8-12-15(19)18-14(20-12)9-13-16-10-6-4-5-7-11(10)17-13/h4-7,9,12H,2-3,8H2,1H3,(H,16,17)(H,18,19)/b14-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445411
(CHEMBL3104657)Show InChI InChI=1S/C13H13N3OS/c1-2-10-13(17)16-12(18-10)7-11-14-8-5-3-4-6-9(8)15-11/h3-7,10H,2H2,1H3,(H,14,15)(H,16,17)/b12-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445409
(CHEMBL3104660)Show InChI InChI=1S/C13H11N3O3S/c17-12(18)5-9-13(19)16-11(20-9)6-10-14-7-3-1-2-4-8(7)15-10/h1-4,6,9H,5H2,(H,14,15)(H,16,19)(H,17,18)/b11-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445422
(CHEMBL3104673)Show InChI InChI=1S/C11H9N3OS/c15-10-6-16-11(14-10)5-9-12-7-3-1-2-4-8(7)13-9/h1-5H,6H2,(H,12,13)(H,14,15)/b11-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445428
(CHEMBL3104667)Show InChI InChI=1S/C12H9N3OS2/c16-10-7-18-12(15-10)5-11-14-9(6-17-11)8-3-1-2-4-13-8/h1-6H,7H2,(H,15,16)/b12-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445417
(CHEMBL3104650)Show InChI InChI=1S/C12H11N3OS/c1-7-12(16)15-11(17-7)6-10-13-8-4-2-3-5-9(8)14-10/h2-7H,1H3,(H,13,14)(H,15,16)/b11-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445408
(CHEMBL3104661)Show InChI InChI=1S/C13H13N3O2S/c17-6-5-10-13(18)16-12(19-10)7-11-14-8-3-1-2-4-9(8)15-11/h1-4,7,10,17H,5-6H2,(H,14,15)(H,16,18)/b12-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445407
(CHEMBL3104662)Show SMILES CCCC1SC(NC1=O)=Cc1nc2c(C)cccc2[nH]1 |w:9.10| Show InChI InChI=1S/C15H17N3OS/c1-3-5-11-15(19)18-13(20-11)8-12-16-10-7-4-6-9(2)14(10)17-12/h4,6-8,11H,3,5H2,1-2H3,(H,16,17)(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445418
(CHEMBL3104649)Show InChI InChI=1S/C14H10N2OS3/c17-11-7-19-12(15-11)5-13-16-14-8-3-1-2-4-9(8)18-6-10(14)20-13/h1-5H,6-7H2,(H,15,17)/b12-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445419
(CHEMBL3104676)Show InChI InChI=1S/C15H12N2OS2/c18-12-8-19-13(16-12)7-14-17-15-10-4-2-1-3-9(10)5-6-11(15)20-14/h1-4,7H,5-6,8H2,(H,16,18)/b13-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445406
(CHEMBL3104663)Show SMILES CCCC1SC(NC1=O)=Cc1nc2ccc(C)cc2[nH]1 |w:9.10| Show InChI InChI=1S/C15H17N3OS/c1-3-4-12-15(19)18-14(20-12)8-13-16-10-6-5-9(2)7-11(10)17-13/h5-8,12H,3-4H2,1-2H3,(H,16,17)(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445423
(CHEMBL3104672)Show InChI InChI=1S/C11H8N2OS2/c14-9-6-15-10(13-9)5-11-12-7-3-1-2-4-8(7)16-11/h1-5H,6H2,(H,13,14)/b10-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445427
(CHEMBL3104668)Show InChI InChI=1S/C7H6N2O2S2/c10-4-2-12-6(8-4)1-7-9-5(11)3-13-7/h1-2,10H,3H2,(H,9,11)/b7-1+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445405
(CHEMBL3104664)Show InChI InChI=1S/C16H19N3OS/c1-4-5-13-16(20)19-15(21-13)8-14-17-11-6-9(2)10(3)7-12(11)18-14/h6-8,13H,4-5H2,1-3H3,(H,17,18)(H,19,20)/b15-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445412
(CHEMBL3104656)Show InChI InChI=1S/C13H13N3OS/c1-7-3-4-9-13(8(7)2)15-10(14-9)5-12-16-11(17)6-18-12/h3-5H,6H2,1-2H3,(H,14,15)(H,16,17) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445420
(CHEMBL3104675)Show InChI InChI=1S/C14H10N2OS2/c17-11-7-18-12(15-11)6-13-16-14-9-4-2-1-3-8(9)5-10(14)19-13/h1-4,6H,5,7H2,(H,15,17)/b12-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445421
(CHEMBL3104674)Show InChI InChI=1S/C15H11N3OS/c19-14-8-20-15(18-14)7-13-16-11-5-9-3-1-2-4-10(9)6-12(11)17-13/h1-7H,8H2,(H,16,17)(H,18,19)/b15-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445416
(CHEMBL3104652)Show InChI InChI=1S/C12H11N3OS/c1-15-9-5-3-2-4-8(9)13-10(15)6-12-14-11(16)7-17-12/h2-6H,7H2,1H3,(H,14,16)/b12-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445414
(CHEMBL3104654)Show InChI InChI=1S/C12H11N3OS/c1-7-2-3-8-9(4-7)14-10(13-8)5-12-15-11(16)6-17-12/h2-5H,6H2,1H3,(H,13,14)(H,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445415
(CHEMBL3104653)Show InChI InChI=1S/C12H11N3OS/c1-7-3-2-4-8-12(7)14-9(13-8)5-11-15-10(16)6-17-11/h2-5H,6H2,1H3,(H,13,14)(H,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445404
(CHEMBL3104665)Show SMILES CCCC1SC(NC1=O)=Cc1nc2ccc(cc2[nH]1)C(F)(F)F |w:9.10| Show InChI InChI=1S/C15H14F3N3OS/c1-2-3-11-14(22)21-13(23-11)7-12-19-9-5-4-8(15(16,17)18)6-10(9)20-12/h4-7,11H,2-3H2,1H3,(H,19,20)(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-14
(Homo sapiens (Human)) | BDBM50445402
(CHEMBL3104658)Show InChI InChI=1S/C14H15N3OS/c1-2-5-11-14(18)17-13(19-11)8-12-15-9-6-3-4-7-10(9)16-12/h3-4,6-8,11H,2,5H2,1H3,(H,15,16)(H,17,18)/b13-8+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP-14 using fluorescence peptide matrix as substrate after 45 mins by fluorescence plate reader analysis |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445425
(CHEMBL3104670)Show InChI InChI=1S/C7H7N3OS/c11-6-3-12-7(10-6)1-5-2-8-4-9-5/h1-2,4H,3H2,(H,8,9)(H,10,11) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445424
(CHEMBL3104671)Show InChI InChI=1S/C11H8N2O2S/c14-9-6-16-11(13-9)5-10-12-7-3-1-2-4-8(7)15-10/h1-5H,6H2,(H,13,14)/b11-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445426
(CHEMBL3104669)Show InChI InChI=1S/C8H7NOS2/c10-7-5-12-8(9-7)4-6-2-1-3-11-6/h1-4H,5H2,(H,9,10)/b8-4+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 5
(Homo sapiens (Human)) | BDBM50445413
(CHEMBL3104655)Show InChI InChI=1S/C13H13N3OS/c1-7-3-9-10(4-8(7)2)15-11(14-9)5-13-16-12(17)6-18-13/h3-5H,6H2,1-2H3,(H,14,15)(H,16,17)/b13-5+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human)) | BDBM50445402
(CHEMBL3104658)Show InChI InChI=1S/C14H15N3OS/c1-2-5-11-14(18)17-13(19-11)8-12-15-9-6-3-4-7-10(9)16-12/h3-4,6-8,11H,2,5H2,1H3,(H,15,16)(H,17,18)/b13-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-4 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50445402
(CHEMBL3104658)Show InChI InChI=1S/C14H15N3OS/c1-2-5-11-14(18)17-13(19-11)8-12-15-9-6-3-4-7-10(9)16-12/h3-4,6-8,11H,2,5H2,1H3,(H,15,16)(H,17,18)/b13-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of TACE (unknown origin) |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human)) | BDBM50431947
(CHEMBL2348091)Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant ADAMTS-4 using interglobular domain peptide of aggrecan after 60 mins by FRET assay |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-14
(Homo sapiens (Human)) | BDBM50431947
(CHEMBL2348091)Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP-14 using fluorescence peptide matrix as substrate after 45 mins by fluorescence plate reader analysis |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50431947
(CHEMBL2348091)Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Kasei Pharma Corporation
Curated by ChEMBL
| Assay Description
Inhibition of TACE (unknown origin) |
Eur J Med Chem 71: 250-8 (2014)
Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15 |
More data for this
Ligand-Target Pair | |
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