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PubMed code 24354364

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))
BDBM17755
PNG
(2-(3-sulfanylpropyl)pentanedioic acid | 2-MPPA | C...)
Show SMILES OC(=O)CCC(CCCS)C(O)=O
Show InChI InChI=1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)
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MCE
PC cid
PC sid
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Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Johns Hopkins University

Curated by ChEMBL


Assay Description
Inhibition of GCP2 (unknown origin)


J Med Chem 57: 243-7 (2014)


Article DOI: 10.1021/jm401703a
BindingDB Entry DOI: 10.7270/Q2HH6MJB
More data for this
Ligand-Target Pair
Glutamate carboxypeptidase 2


(Homo sapiens (Human))
BDBM50446980
PNG
(CHEMBL3116048)
Show SMILES OC(=O)CCC1CCCSC1=O
Show InChI InChI=1S/C8H12O3S/c9-7(10)4-3-6-2-1-5-12-8(6)11/h6H,1-5H2,(H,9,10)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Johns Hopkins University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl[3H]-L-glutamate as substrate


J Med Chem 57: 243-7 (2014)


Article DOI: 10.1021/jm401703a
BindingDB Entry DOI: 10.7270/Q2HH6MJB
More data for this
Ligand-Target Pair
Glutamate carboxypeptidase 2


(Homo sapiens (Human))
BDBM50446979
PNG
(CHEMBL3116049)
Show SMILES OC(=O)c1cccc(c1)-c1cccc2CCSC(=O)c12
Show InChI InChI=1S/C16H12O3S/c17-15(18)12-5-1-4-11(9-12)13-6-2-3-10-7-8-20-16(19)14(10)13/h1-6,9H,7-8H2,(H,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Johns Hopkins University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl[3H]-L-glutamate as substrate


J Med Chem 57: 243-7 (2014)


Article DOI: 10.1021/jm401703a
BindingDB Entry DOI: 10.7270/Q2HH6MJB
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%