Found 14 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007037
(CHEBI:23774 | CHEMBL3237555)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(=O)NC1=O |r| Show InChI InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human cytidine deaminase by spectrophotometrically |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007025
(TETRAHYDROURIDINE)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CC[C@@H](O)NC1=O |r| Show InChI InChI=1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5-,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 4.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human cytidine deaminase by spectrophotometrically |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007030
(CHEMBL3237548)Show SMILES OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1CC[C@@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5-,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007025
(TETRAHYDROURIDINE)Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CC[C@@H](O)NC1=O |r| Show InChI InChI=1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5-,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007029
(CHEMBL3237547)Show SMILES OC[C@H]1O[C@@H](N2CC[C@@H](O)NC2=O)C(F)(F)[C@@H]1O |r| Show InChI InChI=1S/C9H14F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h4-7,14-16H,1-3H2,(H,12,17)/t4-,5-,6-,7-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007031
(CHEMBL3237549)Show SMILES OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)N1CC[C@@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5-,6+,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007033
(CHEMBL3237551)Show SMILES OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1CC[C@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5+,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007034
(CHEMBL3237552)Show SMILES OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)N1CC[C@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5+,6+,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007032
(CHEMBL3237550)Show SMILES OC[C@H]1O[C@@H](N2CC[C@H](O)NC2=O)C(F)(F)[C@@H]1O |r| Show InChI InChI=1S/C9H14F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h4-7,14-16H,1-3H2,(H,12,17)/t4-,5+,6-,7-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007028
(CHEMBL3237546)Show SMILES OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)N1CCC(=O)NC1=O |r| Show InChI InChI=1S/C9H13FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4,6-8,13,15H,1-3H2,(H,11,14,16)/t4-,6+,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007026
(CHEMBL3237544)Show SMILES OC[C@H]1O[C@@H](N2CCC(=O)NC2=O)C(F)(F)[C@@H]1O |r| Show InChI InChI=1S/C9H12F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h4,6-7,14,16H,1-3H2,(H,12,15,17)/t4-,6-,7-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007027
(CHEMBL3237545)Show SMILES OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1CCC(=O)NC1=O |r| Show InChI InChI=1S/C9H13FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4,6-8,13,15H,1-3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007036
(CHEMBL3237554)Show SMILES OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1CCCNC1=O |r| Show InChI InChI=1S/C9H15FN2O4/c10-6-7(14)5(4-13)16-8(6)12-3-1-2-11-9(12)15/h5-8,13-14H,1-4H2,(H,11,15)/t5-,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007035
(CHEMBL3237553)Show SMILES OC[C@H]1O[C@@H](N2CCCNC2=O)C(F)(F)[C@@H]1O |r| Show InChI InChI=1S/C9H14F2N2O4/c10-9(11)6(15)5(4-14)17-7(9)13-3-1-2-12-8(13)16/h5-7,14-15H,1-4H2,(H,12,16)/t5-,6-,7-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
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