BindingDB logo
myBDB logout

PubMed code 24531224

Compile data set for download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449225
PNG
(CHEMBL3127991)
Show SMILES N[C@@H](Cc1csc(n1)-c1cccs1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C15H15FN4OS2/c16-9-4-11(6-17)20(7-9)15(21)12(18)5-10-8-23-14(19-10)13-2-1-3-22-13/h1-3,8-9,11-12H,4-5,7,18H2/t9-,11-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449224
PNG
(CHEMBL3127988)
Show SMILES N[C@@H](Cc1csc(n1)-c1ccccc1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C17H17FN4OS/c18-12-6-14(8-19)22(9-12)17(23)15(20)7-13-10-24-16(21-13)11-4-2-1-3-5-11/h1-5,10,12,14-15H,6-7,9,20H2/t12-,14-,15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449234
PNG
(CHEMBL3127989)
Show SMILES N[C@@H](Cc1csc(n1)-c1ccc(Cl)cc1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C17H16ClFN4OS/c18-11-3-1-10(2-4-11)16-22-13(9-25-16)6-15(21)17(24)23-8-12(19)5-14(23)7-20/h1-4,9,12,14-15H,5-6,8,21H2/t12-,14-,15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449236
PNG
(CHEMBL3127990)
Show SMILES N[C@@H](Cc1csc(n1)-c1ccc(cc1)C(F)(F)F)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C18H16F4N4OS/c19-12-5-14(7-23)26(8-12)17(27)15(24)6-13-9-28-16(25-13)10-1-3-11(4-2-10)18(20,21)22/h1-4,9,12,14-15H,5-6,8,24H2/t12-,14-,15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449236
PNG
(CHEMBL3127990)
Show SMILES N[C@@H](Cc1csc(n1)-c1ccc(cc1)C(F)(F)F)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C18H16F4N4OS/c19-12-5-14(7-23)26(8-12)17(27)15(24)6-13-9-28-16(25-13)10-1-3-11(4-2-10)18(20,21)22/h1-4,9,12,14-15H,5-6,8,24H2/t12-,14-,15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449233
PNG
(CHEMBL3127984)
Show SMILES N[C@@H](Cc1cccs1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C12H14FN3OS/c13-8-4-9(6-14)16(7-8)12(17)11(15)5-10-2-1-3-18-10/h1-3,8-9,11H,4-5,7,15H2/t8-,9-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449235
PNG
(CHEMBL3127986)
Show SMILES N[C@@H](Cc1cscn1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C11H13FN4OS/c12-7-1-9(3-13)16(4-7)11(17)10(14)2-8-5-18-6-15-8/h5-7,9-10H,1-2,4,14H2/t7-,9-,10-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449235
PNG
(CHEMBL3127986)
Show SMILES N[C@@H](Cc1cscn1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C11H13FN4OS/c12-7-1-9(3-13)16(4-7)11(17)10(14)2-8-5-18-6-15-8/h5-7,9-10H,1-2,4,14H2/t7-,9-,10-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449234
PNG
(CHEMBL3127989)
Show SMILES N[C@@H](Cc1csc(n1)-c1ccc(Cl)cc1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C17H16ClFN4OS/c18-11-3-1-10(2-4-11)16-22-13(9-25-16)6-15(21)17(24)23-8-12(19)5-14(23)7-20/h1-4,9,12,14-15H,5-6,8,21H2/t12-,14-,15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449233
PNG
(CHEMBL3127984)
Show SMILES N[C@@H](Cc1cccs1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C12H14FN3OS/c13-8-4-9(6-14)16(7-8)12(17)11(15)5-10-2-1-3-18-10/h1-3,8-9,11H,4-5,7,15H2/t8-,9-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449225
PNG
(CHEMBL3127991)
Show SMILES N[C@@H](Cc1csc(n1)-c1cccs1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C15H15FN4OS2/c16-9-4-11(6-17)20(7-9)15(21)12(18)5-10-8-23-14(19-10)13-2-1-3-22-13/h1-3,8-9,11-12H,4-5,7,18H2/t9-,11-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449232
PNG
(CHEMBL3127985)
Show SMILES N[C@@H](Cc1csc2ccccc12)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C16H16FN3OS/c17-11-6-12(7-18)20(8-11)16(21)14(19)5-10-9-22-15-4-2-1-3-13(10)15/h1-4,9,11-12,14H,5-6,8,19H2/t11-,12-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.20E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449231
PNG
(CHEMBL3127987)
Show SMILES Cc1nc(C[C@H](N)C(=O)N2C[C@@H](F)C[C@H]2C#N)cs1 |r|
Show InChI InChI=1S/C12H15FN4OS/c1-7-16-9(6-19-7)3-11(15)12(18)17-5-8(13)2-10(17)4-14/h6,8,10-11H,2-3,5,15H2,1H3/t8-,10-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449232
PNG
(CHEMBL3127985)
Show SMILES N[C@@H](Cc1csc2ccccc12)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C16H16FN3OS/c17-11-6-12(7-18)20(8-11)16(21)14(19)5-10-9-22-15-4-2-1-3-13(10)15/h1-4,9,11-12,14H,5-6,8,19H2/t11-,12-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449230
PNG
(CHEMBL3127992)
Show SMILES N[C@@H](Cc1cc2OCOc2cc1Br)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C15H15BrFN3O3/c16-11-4-14-13(22-7-23-14)2-8(11)1-12(19)15(21)20-6-9(17)3-10(20)5-18/h2,4,9-10,12H,1,3,6-7,19H2/t9-,10-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449224
PNG
(CHEMBL3127988)
Show SMILES N[C@@H](Cc1csc(n1)-c1ccccc1)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C17H17FN4OS/c18-12-6-14(8-19)22(9-12)17(23)15(20)7-13-10-24-16(21-13)11-4-2-1-3-5-11/h1-5,10,12,14-15H,6-7,9,20H2/t12-,14-,15-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.40E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449231
PNG
(CHEMBL3127987)
Show SMILES Cc1nc(C[C@H](N)C(=O)N2C[C@@H](F)C[C@H]2C#N)cs1 |r|
Show InChI InChI=1S/C12H15FN4OS/c1-7-16-9(6-19-7)3-11(15)12(18)17-5-8(13)2-10(17)4-14/h6,8,10-11H,2-3,5,15H2,1H3/t8-,10-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.80E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449230
PNG
(CHEMBL3127992)
Show SMILES N[C@@H](Cc1cc2OCOc2cc1Br)C(=O)N1C[C@@H](F)C[C@H]1C#N |r|
Show InChI InChI=1S/C15H15BrFN3O3/c16-11-4-14-13(22-7-23-14)2-8(11)1-12(19)15(21)20-6-9(17)3-10(20)5-18/h2,4,9-10,12H,1,3,6-7,19H2/t9-,10-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.50E+3n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449229
PNG
(CHEMBL3127981)
Show SMILES N[C@@H](Cc1csc2ccccc12)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C16H17N3OS/c17-9-12-4-3-7-19(12)16(20)14(18)8-11-10-21-15-6-2-1-5-13(11)15/h1-2,5-6,10,12,14H,3-4,7-8,18H2/t12-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.06E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449228
PNG
(CHEMBL3127982)
Show SMILES N[C@@H](Cc1cscn1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C11H14N4OS/c12-5-9-2-1-3-15(9)11(16)10(13)4-8-6-17-7-14-8/h6-7,9-10H,1-4,13H2/t9-,10-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.15E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449229
PNG
(CHEMBL3127981)
Show SMILES N[C@@H](Cc1csc2ccccc12)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C16H17N3OS/c17-9-12-4-3-7-19(12)16(20)14(18)8-11-10-21-15-6-2-1-5-13(11)15/h1-2,5-6,10,12,14H,3-4,7-8,18H2/t12-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.23E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449228
PNG
(CHEMBL3127982)
Show SMILES N[C@@H](Cc1cscn1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C11H14N4OS/c12-5-9-2-1-3-15(9)11(16)10(13)4-8-6-17-7-14-8/h6-7,9-10H,1-4,13H2/t9-,10-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.39E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM11162
PNG
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F |r|
Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem

Similars
Article
PubMed
n/an/a 3.36E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449227
PNG
(CHEMBL3127980)
Show SMILES N[C@@H](Cc1ccsc1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C12H15N3OS/c13-7-10-2-1-4-15(10)12(16)11(14)6-9-3-5-17-8-9/h3,5,8,10-11H,1-2,4,6,14H2/t10-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.57E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449227
PNG
(CHEMBL3127980)
Show SMILES N[C@@H](Cc1ccsc1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C12H15N3OS/c13-7-10-2-1-4-15(10)12(16)11(14)6-9-3-5-17-8-9/h3,5,8,10-11H,1-2,4,6,14H2/t10-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.24E+4n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM11162
PNG
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F |r|
Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem

Similars
Article
PubMed
n/an/a 1.09E+5n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449226
PNG
(CHEMBL3127983)
Show SMILES N[C@@H](Cc1ccccn1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C13H16N4O/c14-9-11-5-3-7-17(11)13(18)12(15)8-10-4-1-2-6-16-10/h1-2,4,6,11-12H,3,5,7-8,15H2/t11-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449226
PNG
(CHEMBL3127983)
Show SMILES N[C@@H](Cc1ccccn1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C13H16N4O/c14-9-11-5-3-7-17(11)13(18)12(15)8-10-4-1-2-6-16-10/h1-2,4,6,11-12H,3,5,7-8,15H2/t11-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.44E+5n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))		BDBM50449223
PNG
(CHEMBL3127979)
Show SMILES N[C@@H](Cc1ccoc1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C12H15N3O2/c13-7-10-2-1-4-15(10)12(16)11(14)6-9-3-5-17-8-9/h3,5,8,10-11H,1-2,4,6,14H2/t10-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.88E+5n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))		BDBM50449223
PNG
(CHEMBL3127979)
Show SMILES N[C@@H](Cc1ccoc1)C(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C12H15N3O2/c13-7-10-2-1-4-15(10)12(16)11(14)6-9-3-5-17-8-9/h3,5,8,10-11H,1-2,4,6,14H2/t10-,11-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.88E+5n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric...

Eur J Med Chem 75: 111-22 (2014)


Article DOI: 10.1016/j.ejmech.2014.01.021
BindingDB Entry DOI: 10.7270/Q2Z039NP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%