Affinity Data by PubMed id=24564570

PubMed code 24564570

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 \| DB867) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50388602 (FURAMIDINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50388602 (FURAMIDINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.73E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 \| DB867) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 \| DB867) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50388602 (FURAMIDINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.83E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50007728 (CHEMBL424121 \| DB867) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50388602 (FURAMIDINE) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%