Affinity Data by PubMed id=24576797

PubMed code 24576797

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50044258 (CHEMBL3337489) Show SMILES Nn1c(Cn2c(nc3ccccc23)-c2ccco2)n[nH]c1=S Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50044256 (CHEMBL3337482) Show SMILES Cc1ccc(o1)-c1nc2ccccc2n1CC(=O)NN Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM50044257 (CHEMBL3337483) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50044258 (CHEMBL3337489) Show SMILES Nn1c(Cn2c(nc3ccccc23)-c2ccco2)n[nH]c1=S Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50044257 (CHEMBL3337483) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50044256 (CHEMBL3337482) Show SMILES Cc1ccc(o1)-c1nc2ccccc2n1CC(=O)NN Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Research Centre, Dokki Curated by ChEMBL					Assay Description Inhibition of ovine COX1 assessed as reduction in PGH2-dervied PGF2alpha production using arachidonic acid substrate by enzyme immunoassay				Eur J Med Chem 87: 868-80 (2014) Article DOI: 10.1016/j.ejmech.2014.01.063 BindingDB Entry DOI: 10.7270/Q2BK1F0B
National Research Centre, Dokki Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%