Affinity Data by PubMed id=24737316

PubMed code 24737316

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human))	BDBM228800 (NOEV \| Sapienic acid (SpA)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	940	-35.8	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677] (Homo sapiens (Human))	BDBM228800 (NOEV \| Sapienic acid (SpA)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+3	-35.4	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,I51T] (Homo sapiens (Human))	BDBM228800 (NOEV \| Sapienic acid (SpA)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+3	-35.2	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,I51T] (Homo sapiens (Human))	BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.47E+4	-25.8	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human))	BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.90E+4	-25.6	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human))	BDBM228802 (5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	5.33E+4	-25.4	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-galactosidase [24-677] (Homo sapiens (Human))	BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.18E+4	-25.0	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-galactosidase [24-677] (Homo sapiens (Human))	BDBM228802 (5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	6.83E+4	-24.7	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-galactosidase [24-677,I51T] (Homo sapiens (Human))	BDBM228802 (5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	6.88E+4	-24.7	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-galactosidase [24-677] (Homo sapiens (Human))	BDBM228803 (5N,6S-(N'-butyliminomethylidene)-6-thiogalacto...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.53E+5	-21.4	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,I51T] (Homo sapiens (Human))	BDBM228803 (5N,6S-(N'-butyliminomethylidene)-6-thiogalacto...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+5	-20.8	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human))	BDBM228803 (5N,6S-(N'-butyliminomethylidene)-6-thiogalacto...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+5	-20.7	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,I51T] (Homo sapiens (Human))	BDBM228804 (N-(N'-butylthiocarbamoyl)-1-deoxygalactonojiri...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.29E+5	-20.7	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677] (Homo sapiens (Human))	BDBM228804 (N-(N'-butylthiocarbamoyl)-1-deoxygalactonojiri...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.73E+5	-20.4	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human))	BDBM228804 (N-(N'-butylthiocarbamoyl)-1-deoxygalactonojiri...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.88E+5	-20.3	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677] (Homo sapiens (Human))	BDBM228805 (Galactose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	4.14E+6	-14.1	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,I51T] (Homo sapiens (Human))	BDBM228805 (Galactose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	4.91E+6	-13.7	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human))	BDBM228805 (Galactose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	5.61E+6	-13.4	n/a	n/a	n/a	n/a	n/a	4.5	37
The University of Tokyo					Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...				J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4
The University of Tokyo					More data for this Ligand-Target Pair

* indicates data uncertainty>20%