Affinity Data by PubMed id=2479745

PubMed code 2479745

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50016534 (1-(4-azido-5-{[(1,2,3,3-tetrahydroxy-1,2,3-trioxid...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Showa University Curated by ChEMBL					Assay Description Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rA)-oligo(dT) template primer				J Med Chem 32: 2507-9 (1989) BindingDB Entry DOI: 10.7270/Q2HH6J27
Showa University Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50004152 ((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...) Show SMILES Cc1c(Sc2ccccc2)n(COCCO)c(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Showa University Curated by ChEMBL					Assay Description Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rC)-oligo(dG) template primer				J Med Chem 32: 2507-9 (1989) BindingDB Entry DOI: 10.7270/Q2HH6J27
Showa University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50016535 (5-methyl-6-(phenylthio)-1-({2-[(1,2,3,3-tetrahydro...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Showa University Curated by ChEMBL					Assay Description Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rA)-oligo(dT) template primer				J Med Chem 32: 2507-9 (1989) BindingDB Entry DOI: 10.7270/Q2HH6J27
Showa University Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50016535 (5-methyl-6-(phenylthio)-1-({2-[(1,2,3,3-tetrahydro...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Showa University Curated by ChEMBL					Assay Description Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rC)-oligo(dG) template primer				J Med Chem 32: 2507-9 (1989) BindingDB Entry DOI: 10.7270/Q2HH6J27
Showa University Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50004152 ((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...) Show SMILES Cc1c(Sc2ccccc2)n(COCCO)c(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Showa University Curated by ChEMBL					Assay Description Inhibitory effect of the compound on HIV-1 reverse transcriptase activity using poly(rA)-oligo(dT) template primer				J Med Chem 32: 2507-9 (1989) BindingDB Entry DOI: 10.7270/Q2HH6J27
Showa University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%