Affinity Data by PubMed id=24803299

PubMed code 24803299

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM123786 (AAP1742) Show SMILES Nc1n[nH]c(N)c1\N=N\c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM12028 (4-Arylazo-3,5-diamino-1H-pyrazole 31b \| 4-[(E)-2-(...) Show SMILES Nc1n[nH]c(N)c1N=Nc1ccc(O)cc1 \|w:8.9\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM123786 (AAP1742) Show SMILES Nc1n[nH]c(N)c1\N=N\c1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	454	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM123786 (AAP1742) Show SMILES Nc1n[nH]c(N)c1\N=N\c1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	549	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM123786 (AAP1742) Show SMILES Nc1n[nH]c(N)c1\N=N\c1ccncc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM12028 (4-Arylazo-3,5-diamino-1H-pyrazole 31b \| 4-[(E)-2-(...) Show SMILES Nc1n[nH]c(N)c1N=Nc1ccc(O)cc1 \|w:8.9\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM123786 (AAP1742) Show SMILES Nc1n[nH]c(N)c1\N=N\c1ccncc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM12028 (4-Arylazo-3,5-diamino-1H-pyrazole 31b \| 4-[(E)-2-(...) Show SMILES Nc1n[nH]c(N)c1N=Nc1ccc(O)cc1 \|w:8.9\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM12028 (4-Arylazo-3,5-diamino-1H-pyrazole 31b \| 4-[(E)-2-(...) Show SMILES Nc1n[nH]c(N)c1N=Nc1ccc(O)cc1 \|w:8.9\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM12028 (4-Arylazo-3,5-diamino-1H-pyrazole 31b \| 4-[(E)-2-(...) Show SMILES Nc1n[nH]c(N)c1N=Nc1ccc(O)cc1 \|w:8.9\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR and Palacky University					Assay Description Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.				Chem Biol Drug Des 84: 402-8 (2014) Article DOI: 10.1111/cbdd.12330 BindingDB Entry DOI: 10.7270/Q28C9TXB
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%