Affinity Data by PubMed id=24847082

PubMed code 24847082

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
EEF1AKMT4-ECE2 readthrough transcript protein (Homo sapiens (Human))	BDBM231638 (SM19712) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	5.5	n/a
Icahn School of Medicine at Mount Sinai					Assay Description Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...				J Biol Chem 289: 19613-26 (2014) Article DOI: 10.1074/jbc.M113.537704 BindingDB Entry DOI: 10.7270/Q2VD6XBF
Icahn School of Medicine at Mount Sinai					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Homo sapiens (Human))	BDBM231638 (SM19712) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.4	n/a
Icahn School of Medicine at Mount Sinai					Assay Description Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...				J Biol Chem 289: 19613-26 (2014) Article DOI: 10.1074/jbc.M113.537704 BindingDB Entry DOI: 10.7270/Q2VD6XBF
Icahn School of Medicine at Mount Sinai					More data for this Ligand-Target Pair
EEF1AKMT4-ECE2 readthrough transcript protein (Homo sapiens (Human))	BDBM50271179 (2-(2-(quinolin-2-yl)vinyl)phenol \| CHEMBL487942 \| ...) Show SMILES Oc1ccccc1\C=C/c1ccc2ccccc2n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	5.5	n/a
Icahn School of Medicine at Mount Sinai					Assay Description Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...				J Biol Chem 289: 19613-26 (2014) Article DOI: 10.1074/jbc.M113.537704 BindingDB Entry DOI: 10.7270/Q2VD6XBF
Icahn School of Medicine at Mount Sinai					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Homo sapiens (Human))	BDBM231638 (SM19712) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	5.5	n/a
Icahn School of Medicine at Mount Sinai					Assay Description Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...				J Biol Chem 289: 19613-26 (2014) Article DOI: 10.1074/jbc.M113.537704 BindingDB Entry DOI: 10.7270/Q2VD6XBF
Icahn School of Medicine at Mount Sinai					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Homo sapiens (Human))	BDBM50271179 (2-(2-(quinolin-2-yl)vinyl)phenol \| CHEMBL487942 \| ...) Show SMILES Oc1ccccc1\C=C/c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	5.5	n/a
Icahn School of Medicine at Mount Sinai					Assay Description Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...				J Biol Chem 289: 19613-26 (2014) Article DOI: 10.1074/jbc.M113.537704 BindingDB Entry DOI: 10.7270/Q2VD6XBF
Icahn School of Medicine at Mount Sinai					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Homo sapiens (Human))	BDBM50271179 (2-(2-(quinolin-2-yl)vinyl)phenol \| CHEMBL487942 \| ...) Show SMILES Oc1ccccc1\C=C/c1ccc2ccccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.4	n/a
Icahn School of Medicine at Mount Sinai					Assay Description Recombinant ECE2 (32.5 ng) with a specific activity of 12 pmol/min/μg protein was generated as described previously. Secreted soluble recombinan...				J Biol Chem 289: 19613-26 (2014) Article DOI: 10.1074/jbc.M113.537704 BindingDB Entry DOI: 10.7270/Q2VD6XBF
Icahn School of Medicine at Mount Sinai					More data for this Ligand-Target Pair

* indicates data uncertainty>20%