Affinity Data by PubMed id=24878193

PubMed code 24878193

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50085415 (3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of cRAF1 (unknown origin) at 10 uM				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50085415 (3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of BRAF V599E mutant (unknown origin)				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50044784 (CHEBI:79090 \| SB-202190 \| US10865384, Compound SB2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of P38a/MAPK14 (unknown origin)				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50044783 (CHEMBL3309549) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of cRAF1 (unknown origin) at 10 uM				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50085415 (3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of BRAF (unknown origin)				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50044783 (CHEMBL3309549) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of BRAF V599E mutant (unknown origin)				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50044783 (CHEMBL3309549) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of BRAF (unknown origin)				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50044783 (CHEMBL3309549) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	571	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of P38a/MAPK14 (unknown origin)				Bioorg Med Chem Lett 24: 3600-4 (2014) Article DOI: 10.1016/j.bmcl.2014.05.030 BindingDB Entry DOI: 10.7270/Q2RN39HK
Hanyang University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%