Affinity Data by PubMed id=24900598

PubMed code 24900598

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Endothelial lipase (Mus musculus (Mouse))	BDBM50443626 (CHEMBL3092451) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50443626 (CHEMBL3092451) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50443627 (CHEMBL3092450 \| US9216998, 5) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair
Endothelial lipase (Mus musculus (Mouse))	BDBM50443627 (CHEMBL3092450 \| US9216998, 5) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair
Endothelial lipase (Mus musculus (Mouse))	BDBM50443625 (CHEMBL3092448 \| US9216998, 25) Show SMILES FC(F)(F)c1c(CCc2ccccc2)n2CCOc3cccc1c23 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50443625 (CHEMBL3092448 \| US9216998, 25) Show SMILES FC(F)(F)c1c(CCc2ccccc2)n2CCOc3cccc1c23 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair
Endothelial lipase (Mus musculus (Mouse))	BDBM50443624 (CHEMBL3092449 \| US9216998, 28) Show SMILES FC(F)(F)c1c(CCCc2ccccc2)n2CCSc3cccc1c23 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of mouse endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50443624 (CHEMBL3092449 \| US9216998, 28) Show SMILES FC(F)(F)c1c(CCCc2ccccc2)n2CCSc3cccc1c23 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase using PLAi as substrate measured for 30 mins by cell-based fluorescence assay				ACS Med Chem Lett 4: 1016-7 (2013) Article DOI: 10.1021/ml400361q BindingDB Entry DOI: 10.7270/Q22J6DBG
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%