Affinity Data by PubMed id=24984230

PubMed code 24984230

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048422 (CHEMBL3315084) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048421 (CHEMBL3315083) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048446 (CHEMBL3315088) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048447 (CHEMBL3315089) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048476 (CHEMBL3315079) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048477 (CHEMBL3315080) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048443 (CHEMBL3315087) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048463 (CHEMBL3315072) Show SMILES COc1ccc(cc1OC)C(=O)Cc1c(Cl)cncc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048474 (CHEMBL3315077) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048424 (CHEMBL3315086) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048478 (CHEMBL3315081) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50041866 (CHEMBL48017 \| N-(3,5-Dichloro-pyridin-4-yl)-3,4-di...) Show SMILES COc1ccc(cc1OC)C(=O)Nc1c(Cl)cncc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048455 (CHEMBL3315090) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048475 (CHEMBL3315078) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048423 (CHEMBL3315085) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048473 (CHEMBL3315076) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048470 (CHEMBL3313943) Show SMILES CCOc1c(OC)ccc(C(=O)Cc2c(Cl)cncc2Cl)c1OC Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048464 (CHEMBL3315073) Show SMILES COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)c(OC)c1OC Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048471 (CHEMBL3315074) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048472 (CHEMBL3315075) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048420 (CHEMBL3315082) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50048459 (CHEMBL3315071) Show SMILES COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c(OC)c1OC Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
LEO Pharma A/S Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMP				J Med Chem 57: 5893-903 (2014) Article DOI: 10.1021/jm500378a BindingDB Entry DOI: 10.7270/Q2CV4KC4
LEO Pharma A/S Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%