Found 78 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050860
(CHEMBL3318034)Show SMILES Cn1cc(cn1)-c1cnc2c(NC(=O)NCc3ccccc3)ccnc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-24-26)15-9-18-19(22-11-15)17(7-8-21-18)25-20(27)23-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,21,23,25,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050861
(CHEMBL3318035)Show SMILES Cn1cc(cn1)-c1cnc2c(NC(=O)NCCc3ccccc3)ccnc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-25-27)16-11-19-20(24-12-16)18(8-10-22-19)26-21(28)23-9-7-15-5-3-2-4-6-15/h2-6,8,10-14H,7,9H2,1H3,(H2,22,23,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050858
(CHEMBL3318032)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-13-5-6-18-14-7-11(8-19-15(13)14)12-9-20-23(4)10-12/h5-10H,1-4H3,(H2,18,21,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050855
(CHEMBL3318008)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-14-7-8-21-15-9-13(11-22-18(14)15)12-5-6-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,21,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 171 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 227 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 429 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 579 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 624 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 702 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050856
(CHEMBL3318009)Show SMILES COc1ccc(cc1OC)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-15-8-9-22-16-10-14(12-23-19(15)16)13-6-7-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,22,24,25,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 714 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 733 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 742 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 805 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050859
(CHEMBL3318033)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-22-25)13-9-17-18(21-10-13)16(7-8-20-17)24-19(26)23-15-5-3-2-4-6-15/h2-12H,1H3,(H2,20,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050857
(CHEMBL3318031)Show SMILES COc1cc(ccc1O)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-14-7-8-21-15-9-13(11-22-18(14)15)12-5-6-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,21,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050858
(CHEMBL3318032)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-13-5-6-18-14-7-11(8-19-15(13)14)12-9-20-23(4)10-12/h5-10H,1-4H3,(H2,18,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050860
(CHEMBL3318034)Show SMILES Cn1cc(cn1)-c1cnc2c(NC(=O)NCc3ccccc3)ccnc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-24-26)15-9-18-19(22-11-15)17(7-8-21-18)25-20(27)23-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,21,23,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050861
(CHEMBL3318035)Show SMILES Cn1cc(cn1)-c1cnc2c(NC(=O)NCCc3ccccc3)ccnc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-25-27)16-11-19-20(24-12-16)18(8-10-22-19)26-21(28)23-9-7-15-5-3-2-4-6-15/h2-6,8,10-14H,7,9H2,1H3,(H2,22,23,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050857
(CHEMBL3318031)Show SMILES COc1cc(ccc1O)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-14-7-8-21-15-9-13(11-22-18(14)15)12-5-6-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,21,23,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050855
(CHEMBL3318008)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-14-7-8-21-15-9-13(11-22-18(14)15)12-5-6-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,21,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of PIM1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050856
(CHEMBL3318009)Show SMILES COc1ccc(cc1OC)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-15-8-9-22-16-10-14(12-23-19(15)16)13-6-7-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,22,24,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050849
(CHEMBL3318025)Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-19-9-7-15-16(23-19)10-14(12-22-15)13-6-8-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,23,24,25,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050852
(CHEMBL3318030)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCc3ccccc3)nc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-24-27)16-11-19-18(23-12-16)7-8-20(25-19)26-21(28)22-10-9-15-5-3-2-4-6-15/h2-8,11-14H,9-10H2,1H3,(H2,22,25,26,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050847
(CHEMBL3318027)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-15-6-5-13-14(20-15)7-11(8-18-13)12-9-19-23(4)10-12/h5-10H,1-4H3,(H2,20,21,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050859
(CHEMBL3318033)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-22-25)13-9-17-18(21-10-13)16(7-8-20-17)24-19(26)23-15-5-3-2-4-6-15/h2-12H,1H3,(H2,20,23,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050850
(CHEMBL3318024)Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Yes
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of YES (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of KDR (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50050851
(CHEMBL3318023)Show InChI InChI=1S/C18H18N4O2/c1-3-19-18(23)22-17-9-8-15-16(21-17)10-13(11-20-15)12-4-6-14(24-2)7-5-12/h4-11H,3H2,1-2H3,(H2,19,21,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of TrkA (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050848
(CHEMBL3318026)Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NC(=O)NC(C)(C)C)nc2c1 Show InChI InChI=1S/C20H22N4O3/c1-20(2,3)24-19(26)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25)17(10-12)27-4/h5-11,25H,1-4H3,(H2,22,23,24,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50050853
(CHEMBL3318029)Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of c-Abl (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human)) | BDBM50050854
(CHEMBL3318028)Show InChI InChI=1S/C19H16N6O/c1-25-12-14(11-21-25)13-9-17-16(20-10-13)7-8-18(23-17)24-19(26)22-15-5-3-2-4-6-15/h2-12H,1H3,(H2,22,23,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of HIPK1 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |