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PubMed code 25027802

Compile data set for download or QSAR
Found 56 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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PubMed
5.70n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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12n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051110
PNG
(CHEMBL3310914)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C19H31N3O4S/c1-3-10-22(11-4-2)27(24,25)18-7-5-17(6-8-18)19(23)20-9-12-21-13-15-26-16-14-21/h5-8H,3-4,9-16H2,1-2H3,(H,20,23)
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15n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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25n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051111
PNG
(CHEMBL3310913)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1C
Show InChI InChI=1/C20H32N2O3S/c1-4-14-22(15-5-2)26(24,25)18-12-10-17(11-13-18)20(23)21-19-9-7-6-8-16(19)3/h10-13,16,19H,4-9,14-15H2,1-3H3,(H,21,23)
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43n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051113
PNG
(CHEMBL3310911)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC
Show InChI InChI=1S/C14H22N2O3S/c1-4-10-16(11-5-2)20(18,19)13-8-6-12(7-9-13)14(17)15-3/h6-9H,4-5,10-11H2,1-3H3,(H,15,17)
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165n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051109
PNG
(CHEMBL3310915)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H24N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h5-13H,3-4,14-15H2,1-2H3,(H,20,22)
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171n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051103
PNG
(CHEMBL3311027)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-13-21(14-4-2)28(26,27)16-11-9-15(10-12-16)19(23)20-17-7-5-6-8-18(17)22(24)25/h5-12H,3-4,13-14H2,1-2H3,(H,20,23)
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192n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051106
PNG
(CHEMBL3311024)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-12-22(13-4-2)26(24,25)18-10-8-15(9-11-18)19(23)21-17-7-5-6-16(20)14-17/h5-11,14H,3-4,12-13H2,1-2H3,(H,21,23)
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198n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051104
PNG
(CHEMBL3311026)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-12-21(13-4-2)28(26,27)18-10-8-15(9-11-18)19(23)20-16-6-5-7-17(14-16)22(24)25/h5-11,14H,3-4,12-13H2,1-2H3,(H,20,23)
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201n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051107
PNG
(CHEMBL3311023)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1nncs1
Show InChI InChI=1S/C15H20N4O3S2/c1-3-9-19(10-4-2)24(21,22)13-7-5-12(6-8-13)14(20)17-15-18-16-11-23-15/h5-8,11H,3-4,9-10H2,1-2H3,(H,17,18,20)
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216n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051102
PNG
(CHEMBL3311028)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C19H25N3O3S/c1-3-13-22(14-4-2)26(24,25)16-11-9-15(10-12-16)19(23)21-18-8-6-5-7-17(18)20/h5-12H,3-4,13-14,20H2,1-2H3,(H,21,23)
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223n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051108
PNG
(CHEMBL3310916)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccn1
Show InChI InChI=1S/C18H23N3O3S/c1-3-13-21(14-4-2)25(23,24)16-10-8-15(9-11-16)18(22)20-17-7-5-6-12-19-17/h5-12H,3-4,13-14H2,1-2H3,(H,19,20,22)
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228n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051112
PNG
(CHEMBL3310912)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h10-13,17H,3-9,14-15H2,1-2H3,(H,20,22)
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234n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051105
PNG
(CHEMBL3311025)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-13-22(14-4-2)26(24,25)18-11-5-15(6-12-18)19(23)21-17-9-7-16(20)8-10-17/h5-12H,3-4,13-14H2,1-2H3,(H,21,23)
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243n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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250n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051110
PNG
(CHEMBL3310914)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C19H31N3O4S/c1-3-10-22(11-4-2)27(24,25)18-7-5-17(6-8-18)19(23)20-9-12-21-13-15-26-16-14-21/h5-8H,3-4,9-16H2,1-2H3,(H,20,23)
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251n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051111
PNG
(CHEMBL3310913)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1C
Show InChI InChI=1/C20H32N2O3S/c1-4-14-22(15-5-2)26(24,25)18-12-10-17(11-13-18)20(23)21-19-9-7-6-8-16(19)3/h10-13,16,19H,4-9,14-15H2,1-3H3,(H,21,23)
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260n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50051104
PNG
(CHEMBL3311026)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-12-21(13-4-2)28(26,27)18-10-8-15(9-11-18)19(23)20-16-6-5-7-17(14-16)22(24)25/h5-11,14H,3-4,12-13H2,1-2H3,(H,20,23)
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265n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051113
PNG
(CHEMBL3310911)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC
Show InChI InChI=1S/C14H22N2O3S/c1-4-10-16(11-5-2)20(18,19)13-8-6-12(7-9-13)14(17)15-3/h6-9H,4-5,10-11H2,1-3H3,(H,15,17)
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289n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051112
PNG
(CHEMBL3310912)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h10-13,17H,3-9,14-15H2,1-2H3,(H,20,22)
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PubMed
307n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051111
PNG
(CHEMBL3310913)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1C
Show InChI InChI=1/C20H32N2O3S/c1-4-14-22(15-5-2)26(24,25)18-12-10-17(11-13-18)20(23)21-19-9-7-6-8-16(19)3/h10-13,16,19H,4-9,14-15H2,1-3H3,(H,21,23)
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319n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051109
PNG
(CHEMBL3310915)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H24N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h5-13H,3-4,14-15H2,1-2H3,(H,20,22)
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324n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051108
PNG
(CHEMBL3310916)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccn1
Show InChI InChI=1S/C18H23N3O3S/c1-3-13-21(14-4-2)25(23,24)16-10-8-15(9-11-16)18(22)20-17-7-5-6-12-19-17/h5-12H,3-4,13-14H2,1-2H3,(H,19,20,22)
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324n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051103
PNG
(CHEMBL3311027)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-13-21(14-4-2)28(26,27)16-11-9-15(10-12-16)19(23)20-17-7-5-6-8-18(17)22(24)25/h5-12H,3-4,13-14H2,1-2H3,(H,20,23)
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327n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051106
PNG
(CHEMBL3311024)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-12-22(13-4-2)26(24,25)18-10-8-15(9-11-18)19(23)21-17-7-5-6-16(20)14-17/h5-11,14H,3-4,12-13H2,1-2H3,(H,21,23)
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341n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051104
PNG
(CHEMBL3311026)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-12-21(13-4-2)28(26,27)18-10-8-15(9-11-18)19(23)20-16-6-5-7-17(14-16)22(24)25/h5-11,14H,3-4,12-13H2,1-2H3,(H,20,23)
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344n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051107
PNG
(CHEMBL3311023)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1nncs1
Show InChI InChI=1S/C15H20N4O3S2/c1-3-9-19(10-4-2)24(21,22)13-7-5-12(6-8-13)14(20)17-15-18-16-11-23-15/h5-8,11H,3-4,9-10H2,1-2H3,(H,17,18,20)
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346n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051110
PNG
(CHEMBL3310914)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C19H31N3O4S/c1-3-10-22(11-4-2)27(24,25)18-7-5-17(6-8-18)19(23)20-9-12-21-13-15-26-16-14-21/h5-8H,3-4,9-16H2,1-2H3,(H,20,23)
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347n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051103
PNG
(CHEMBL3311027)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-13-21(14-4-2)28(26,27)16-11-9-15(10-12-16)19(23)20-17-7-5-6-8-18(17)22(24)25/h5-12H,3-4,13-14H2,1-2H3,(H,20,23)
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352n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051102
PNG
(CHEMBL3311028)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C19H25N3O3S/c1-3-13-22(14-4-2)26(24,25)16-11-9-15(10-12-16)19(23)21-18-8-6-5-7-17(18)20/h5-12H,3-4,13-14,20H2,1-2H3,(H,21,23)
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354n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50206509
PNG
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
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360n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051105
PNG
(CHEMBL3311025)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-13-22(14-4-2)26(24,25)18-11-5-15(6-12-18)19(23)21-17-9-7-16(20)8-10-17/h5-12H,3-4,13-14H2,1-2H3,(H,21,23)
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364n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051112
PNG
(CHEMBL3310912)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h10-13,17H,3-9,14-15H2,1-2H3,(H,20,22)
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398n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051102
PNG
(CHEMBL3311028)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C19H25N3O3S/c1-3-13-22(14-4-2)26(24,25)16-11-9-15(10-12-16)19(23)21-18-8-6-5-7-17(18)20/h5-12H,3-4,13-14,20H2,1-2H3,(H,21,23)
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407n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051107
PNG
(CHEMBL3311023)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1nncs1
Show InChI InChI=1S/C15H20N4O3S2/c1-3-9-19(10-4-2)24(21,22)13-7-5-12(6-8-13)14(20)17-15-18-16-11-23-15/h5-8,11H,3-4,9-10H2,1-2H3,(H,17,18,20)
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410n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051108
PNG
(CHEMBL3310916)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccn1
Show InChI InChI=1S/C18H23N3O3S/c1-3-13-21(14-4-2)25(23,24)16-10-8-15(9-11-16)18(22)20-17-7-5-6-12-19-17/h5-12H,3-4,13-14H2,1-2H3,(H,19,20,22)
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418n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051109
PNG
(CHEMBL3310915)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H24N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h5-13H,3-4,14-15H2,1-2H3,(H,20,22)
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422n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051106
PNG
(CHEMBL3311024)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-12-22(13-4-2)26(24,25)18-10-8-15(9-11-18)19(23)21-17-7-5-6-16(20)14-17/h5-11,14H,3-4,12-13H2,1-2H3,(H,21,23)
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428n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50051105
PNG
(CHEMBL3311025)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-13-22(14-4-2)26(24,25)18-11-5-15(6-12-18)19(23)21-17-9-7-16(20)8-10-17/h5-12H,3-4,13-14H2,1-2H3,(H,21,23)
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430n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50206509
PNG
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
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431n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM50206509
PNG
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
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1.25E+3n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50051113
PNG
(CHEMBL3310911)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC
Show InChI InChI=1S/C14H22N2O3S/c1-4-10-16(11-5-2)20(18,19)13-8-6-12(7-9-13)14(17)15-3/h6-9H,4-5,10-11H2,1-3H3,(H,15,17)
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1.98E+3n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051105
PNG
(CHEMBL3311025)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-13-22(14-4-2)26(24,25)18-11-5-15(6-12-18)19(23)21-17-9-7-16(20)8-10-17/h5-12H,3-4,13-14H2,1-2H3,(H,21,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50206509
PNG
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051109
PNG
(CHEMBL3310915)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H24N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h5-13H,3-4,14-15H2,1-2H3,(H,20,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051111
PNG
(CHEMBL3310913)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1C
Show InChI InChI=1/C20H32N2O3S/c1-4-14-22(15-5-2)26(24,25)18-12-10-17(11-13-18)20(23)21-19-9-7-6-8-16(19)3/h10-13,16,19H,4-9,14-15H2,1-3H3,(H,21,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051102
PNG
(CHEMBL3311028)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C19H25N3O3S/c1-3-13-22(14-4-2)26(24,25)16-11-9-15(10-12-16)19(23)21-18-8-6-5-7-17(18)20/h5-12H,3-4,13-14,20H2,1-2H3,(H,21,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051110
PNG
(CHEMBL3310914)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C19H31N3O4S/c1-3-10-22(11-4-2)27(24,25)18-7-5-17(6-8-18)19(23)20-9-12-21-13-15-26-16-14-21/h5-8H,3-4,9-16H2,1-2H3,(H,20,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051106
PNG
(CHEMBL3311024)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C19H23ClN2O3S/c1-3-12-22(13-4-2)26(24,25)18-10-8-15(9-11-18)19(23)21-17-7-5-6-16(20)14-17/h5-11,14H,3-4,12-13H2,1-2H3,(H,21,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051104
PNG
(CHEMBL3311026)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-12-21(13-4-2)28(26,27)18-10-8-15(9-11-18)19(23)20-16-6-5-7-17(14-16)22(24)25/h5-11,14H,3-4,12-13H2,1-2H3,(H,20,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051113
PNG
(CHEMBL3310911)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC
Show InChI InChI=1S/C14H22N2O3S/c1-4-10-16(11-5-2)20(18,19)13-8-6-12(7-9-13)14(17)15-3/h6-9H,4-5,10-11H2,1-3H3,(H,15,17)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051107
PNG
(CHEMBL3311023)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1nncs1
Show InChI InChI=1S/C15H20N4O3S2/c1-3-9-19(10-4-2)24(21,22)13-7-5-12(6-8-13)14(20)17-15-18-16-11-23-15/h5-8,11H,3-4,9-10H2,1-2H3,(H,17,18,20)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051103
PNG
(CHEMBL3311027)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccc1[N+]([O-])=O
Show InChI InChI=1S/C19H23N3O5S/c1-3-13-21(14-4-2)28(26,27)16-11-9-15(10-12-16)19(23)20-17-7-5-6-8-18(17)22(24)25/h5-12H,3-4,13-14H2,1-2H3,(H,20,23)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051108
PNG
(CHEMBL3310916)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccccn1
Show InChI InChI=1S/C18H23N3O3S/c1-3-13-21(14-4-2)25(23,24)16-10-8-15(9-11-16)18(22)20-17-7-5-6-12-19-17/h5-12H,3-4,13-14H2,1-2H3,(H,19,20,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50051112
PNG
(CHEMBL3310912)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-3-14-21(15-4-2)25(23,24)18-12-10-16(11-13-18)19(22)20-17-8-6-5-7-9-17/h10-13,17H,3-9,14-15H2,1-2H3,(H,20,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem 22: 3982-8 (2014)


Article DOI: 10.1016/j.bmc.2014.06.003
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%