Found 9 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50139013
((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from MOR in rat brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50053573
(CHEMBL3327220)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H]([C@H](C1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C38H41N5O5/c39-32(20-27-16-18-29(44)19-17-27)38(48)43-23-30(28-14-8-3-9-15-28)31(24-43)36(46)42-34(22-26-12-6-2-7-13-26)37(47)41-33(35(40)45)21-25-10-4-1-5-11-25/h1-19,30-34,44H,20-24,39H2,(H2,40,45)(H,41,47)(H,42,46)/t30-,31+,32+,33+,34+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.850 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from MOR in rat brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50053572
(CHEMBL3327221)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@H]([C@@H](C1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C38H41N5O5/c39-32(20-27-16-18-29(44)19-17-27)38(48)43-23-30(28-14-8-3-9-15-28)31(24-43)36(46)42-34(22-26-12-6-2-7-13-26)37(47)41-33(35(40)45)21-25-10-4-1-5-11-25/h1-19,30-34,44H,20-24,39H2,(H2,40,45)(H,41,47)(H,42,46)/t30-,31+,32-,33-,34-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from MOR in rat brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50053573
(CHEMBL3327220)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H]([C@H](C1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C38H41N5O5/c39-32(20-27-16-18-29(44)19-17-27)38(48)43-23-30(28-14-8-3-9-15-28)31(24-43)36(46)42-34(22-26-12-6-2-7-13-26)37(47)41-33(35(40)45)21-25-10-4-1-5-11-25/h1-19,30-34,44H,20-24,39H2,(H2,40,45)(H,41,47)(H,42,46)/t30-,31+,32+,33+,34+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H](Ile5,6)deltorphin-2 from DOR in rat brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50053573
(CHEMBL3327220)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H]([C@H](C1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C38H41N5O5/c39-32(20-27-16-18-29(44)19-17-27)38(48)43-23-30(28-14-8-3-9-15-28)31(24-43)36(46)42-34(22-26-12-6-2-7-13-26)37(47)41-33(35(40)45)21-25-10-4-1-5-11-25/h1-19,30-34,44H,20-24,39H2,(H2,40,45)(H,41,47)(H,42,46)/t30-,31+,32+,33+,34+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H]nor-BNI from KOR in guinea pig brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50053572
(CHEMBL3327221)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@H]([C@@H](C1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C38H41N5O5/c39-32(20-27-16-18-29(44)19-17-27)38(48)43-23-30(28-14-8-3-9-15-28)31(24-43)36(46)42-34(22-26-12-6-2-7-13-26)37(47)41-33(35(40)45)21-25-10-4-1-5-11-25/h1-19,30-34,44H,20-24,39H2,(H2,40,45)(H,41,47)(H,42,46)/t30-,31+,32-,33-,34-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H](Ile5,6)deltorphin-2 from DOR in rat brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50139013
((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H](Ile5,6)deltorphin-2 from DOR in rat brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50053572
(CHEMBL3327221)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@H]([C@@H](C1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C38H41N5O5/c39-32(20-27-16-18-29(44)19-17-27)38(48)43-23-30(28-14-8-3-9-15-28)31(24-43)36(46)42-34(22-26-12-6-2-7-13-26)37(47)41-33(35(40)45)21-25-10-4-1-5-11-25/h1-19,30-34,44H,20-24,39H2,(H2,40,45)(H,41,47)(H,42,46)/t30-,31+,32-,33-,34-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H]nor-BNI from KOR in guinea pig brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50139013
((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lodz
Curated by ChEMBL
| Assay Description
Displacement of [3H]nor-BNI from KOR in guinea pig brain membranes |
Bioorg Med Chem 22: 4803-9 (2014)
Article DOI: 10.1016/j.bmc.2014.06.056
BindingDB Entry DOI: 10.7270/Q2251KT4 |
More data for this
Ligand-Target Pair | |
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