BindingDB logo
myBDB logout

PubMed code 25122135

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5'-AMP-activated protein kinase catalytic subunit alpha-1


(Homo sapiens (Human))		BDBM50434272
PNG
(CHEMBL1242297)
Show SMILES Cc1cc(-c2ccc(\C=C3/S\C(NC3=O)=N/c3ccc(Cl)c(c3)C(O)=O)o2)c(cc1C)[N+]([O-])=O
Show InChI InChI=1S/C23H16ClN3O6S/c1-11-7-16(18(27(31)32)8-12(11)2)19-6-4-14(33-19)10-20-21(28)26-23(34-20)25-13-3-5-17(24)15(9-13)22(29)30/h3-10H,1-2H3,(H,29,30)(H,25,26,28)/b20-10-
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 8.00E+3n/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Activation of human recombinant AMPK alpha1 subunit

J Med Chem 58: 2-29 (2015)


Article DOI: 10.1021/jm401994c
BindingDB Entry DOI: 10.7270/Q2KH0PZW
More data for this
Ligand-Target Pair
Adiponectin receptor protein 1


(Homo sapiens (Human))		BDBM50059083
PNG
(CHEMBL3393145)
Show SMILES O=C(COc1ccc(cc1)C(=O)c1ccccc1)NC1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 1.80E+3n/an/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Binding affinity to AdipoR1 (unknown origin) by surface plasmon resonance analysis

J Med Chem 58: 2-29 (2015)


Article DOI: 10.1021/jm401994c
BindingDB Entry DOI: 10.7270/Q2KH0PZW
More data for this
Ligand-Target Pair
Adiponectin receptor protein 2


(Homo sapiens (Human))		BDBM50059083
PNG
(CHEMBL3393145)
Show SMILES O=C(COc1ccc(cc1)C(=O)c1ccccc1)NC1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 3.10E+3n/an/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Binding affinity to AdipoR2 (unknown origin) by surface plasmon resonance analysis

J Med Chem 58: 2-29 (2015)


Article DOI: 10.1021/jm401994c
BindingDB Entry DOI: 10.7270/Q2KH0PZW
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%