Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus) | BDBM61947 (6-bromanyl-2-phenyl-1,2-benzothiazol-3-one | 6-bro...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61939 (5,6-bis(fluoranyl)-2-phenyl-1,2-benzothiazol-3-one...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61966 (KSC-09-149B | KUC105615N | N-(2-chlorophenyl)-2-(3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM46667 (2-phenyl-1,2-benzothiazol-3-one | 2-phenyl-1,2-ben...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61969 (KSC-09-140B | KUC105618N | N-(2-bromophenyl)-2-(3-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61942 (2-(3-keto-1,2-benzothiazol-2-yl)-N-(o-tolyl)acetam...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61942 (2-(3-keto-1,2-benzothiazol-2-yl)-N-(o-tolyl)acetam...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61965 (KSC-09-149A | KUC105614N | N-(2-fluorophenyl)-2-(3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61964 (2-(3-keto-1,2-benzothiazol-2-yl)-N-phenyl-propiona...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61970 (KSC-09-140C | KUC105619N | N-(2-iodanylphenyl)-2-(...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61949 (KSC-4-295 | KUC105342N | N-(3-bromophenyl)-2-(3-ke...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61957 (3-(3-keto-1,2-benzothiazol-2-yl)-N-phenyl-propiona...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123128 (1‐(4‐bromo‐2‐nitrophenyl)p...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123129 (1-(3-nitro-phenyl)-pyrrole-2,5-dione (17) | CID236...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61961 (2-(3-keto-1,2-benzothiazol-2-yl)-N-[2-(trifluorome...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM123130 (1-(2-bromo-4-methylphenyl)-1H-pyrrole-2,5-dione (1...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM61938 (1-methyl-2-phenyl-3-indazolone | 1-methyl-2-phenyl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50247587 (2,5-diphenylisothiazol-3(2H)-one | CHEMBL500224 | ...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50220832 (CHEMBL8211 | N-ethylmaleimide) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30E+5 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50376514 (IODOACETAMIDE) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+6 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Wisconsin-Milwaukee | Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi... | ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH | |||||||||||
More data for this Ligand-Target Pair |