Affinity Data by PubMed id=25264478

PubMed code 25264478

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50102732 (CHEMBL3335711) Show SMILES Clc1ccc(Nc2cn[nH]n2)cc1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of intracellular IDO1 activity in human HeLa cells assessed as L-kynurenine production by Ehrlichs test				ACS Med Chem Lett 5: 958-60 (2014) Article DOI: 10.1021/ml5002773 BindingDB Entry DOI: 10.7270/Q2J38VBG
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50102740 (CHEMBL3335706) Show SMILES CCc1cc(Cl)ccc1Nc1cnn[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of intracellular IDO1 activity in human HeLa cells assessed as L-kynurenine production by Ehrlichs test				ACS Med Chem Lett 5: 958-60 (2014) Article DOI: 10.1021/ml5002773 BindingDB Entry DOI: 10.7270/Q2J38VBG
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50102733 (CHEMBL3335710) Show SMILES Cc1cc(F)ccc1Nc1c[nH]nn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of intracellular IDO1 activity in human HeLa cells assessed as L-kynurenine production by Ehrlichs test				ACS Med Chem Lett 5: 958-60 (2014) Article DOI: 10.1021/ml5002773 BindingDB Entry DOI: 10.7270/Q2J38VBG
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50102739 (CHEMBL3335707) Show SMILES CCc1cc(Nc2cnn[nH]2)ccc1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of intracellular IDO1 activity in human HeLa cells assessed as L-kynurenine production by Ehrlichs test				ACS Med Chem Lett 5: 958-60 (2014) Article DOI: 10.1021/ml5002773 BindingDB Entry DOI: 10.7270/Q2J38VBG
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50102736 (CHEMBL3335708) Show SMILES CS(=O)(=O)NCc1cc(Cl)ccc1Nc1cnn[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of intracellular IDO1 activity in human HeLa cells assessed as L-kynurenine production by Ehrlichs test				ACS Med Chem Lett 5: 958-60 (2014) Article DOI: 10.1021/ml5002773 BindingDB Entry DOI: 10.7270/Q2J38VBG
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50102734 (CHEMBL3335709) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of intracellular IDO1 activity in human HeLa cells assessed as L-kynurenine production by Ehrlichs test				ACS Med Chem Lett 5: 958-60 (2014) Article DOI: 10.1021/ml5002773 BindingDB Entry DOI: 10.7270/Q2J38VBG
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%