Found 54 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50277784
(CHEMBL484928 | N,N,2-trimethyl-5-nitrobenzenesulfo...)Show InChI InChI=1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028886
(CHEMBL3359633)Show InChI InChI=1S/C11H7ClN2O2S/c12-10-7-8(14(15)16)1-2-11(10)17-9-3-5-13-6-4-9/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028926
(CHEMBL3359624)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-1-6-12(11(7-8)15(16)17)18-10-4-2-9(14)3-5-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50028886
(CHEMBL3359633)Show InChI InChI=1S/C11H7ClN2O2S/c12-10-7-8(14(15)16)1-2-11(10)17-9-3-5-13-6-4-9/h1-7H | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028887
(CHEMBL3359635)Show InChI InChI=1S/C11H7ClN2O2S/c12-8-1-2-11(10(7-8)14(15)16)17-9-3-5-13-6-4-9/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028925
(CHEMBL3359111)Show InChI InChI=1S/C12H7BrClNO2S/c13-9-3-1-2-4-11(9)18-12-6-5-8(14)7-10(12)15(16)17/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028917
(CHEMBL3359103)Show InChI InChI=1S/C12H7BrClNO2S/c13-9-3-1-2-4-11(9)18-12-7-8(14)5-6-10(12)15(16)17/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50359737
(CHEMBL1927722)Show InChI InChI=1S/C14H10N2S2/c17-13-11-8-4-5-9-12(11)15-14(18)16(13)10-6-2-1-3-7-10/h1-9H,(H,15,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7 (unknown origin) |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50028894
(CHEMBL3359649)Show InChI InChI=1S/C16H15N3OS.BrH/c20-12-11-17-16-18-15(13-7-3-1-4-8-13)19(21-16)14-9-5-2-6-10-14;/h1-10,20H,11-12H2;1H/b17-16-; | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7 (unknown origin) |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50277784
(CHEMBL484928 | N,N,2-trimethyl-5-nitrobenzenesulfo...)Show InChI InChI=1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028935
(CHEMBL3359632)Show InChI InChI=1S/C11H7ClN2O2S/c12-9-7-8(14(15)16)4-5-10(9)17-11-3-1-2-6-13-11/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50028925
(CHEMBL3359111)Show InChI InChI=1S/C12H7BrClNO2S/c13-9-3-1-2-4-11(9)18-12-6-5-8(14)7-10(12)15(16)17/h1-7H | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028916
(CHEMBL3359101)Show InChI InChI=1S/C12H9ClN2O2S/c13-11-7-10(5-6-12(11)15(16)17)18-9-3-1-8(14)2-4-9/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028927
(CHEMBL196910)Show InChI InChI=1S/C12H8ClNO2S/c13-9-6-7-12(11(8-9)14(15)16)17-10-4-2-1-3-5-10/h1-8H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50028927
(CHEMBL196910)Show InChI InChI=1S/C12H8ClNO2S/c13-9-6-7-12(11(8-9)14(15)16)17-10-4-2-1-3-5-10/h1-8H | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028932
(CHEMBL3359631)Show InChI InChI=1S/C10H6ClNO2S2/c11-7-3-4-9(8(6-7)12(13)14)16-10-2-1-5-15-10/h1-6H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50277784
(CHEMBL484928 | N,N,2-trimethyl-5-nitrobenzenesulfo...)Show InChI InChI=1S/C9H12N2O4S/c1-7-4-5-8(11(12)13)6-9(7)16(14,15)10(2)3/h4-6H,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028936
(CHEMBL3359634)Show InChI InChI=1S/C11H7ClN2O2S/c12-8-1-2-10(14(15)16)11(7-8)17-9-3-5-13-6-4-9/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028896
(CHEMBL3359093)Show InChI InChI=1S/C14H11ClN2O3S/c1-9(18)16-11-4-2-3-5-13(11)21-14-8-10(15)6-7-12(14)17(19)20/h2-8H,1H3,(H,16,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028918
(CHEMBL3359104)Show InChI InChI=1S/C12H7BrClNO2S/c13-9-3-1-2-4-11(9)18-12-6-5-8(15(16)17)7-10(12)14/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50028917
(CHEMBL3359103)Show InChI InChI=1S/C12H7BrClNO2S/c13-9-3-1-2-4-11(9)18-12-7-8(14)5-6-10(12)15(16)17/h1-7H | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028928
(CHEMBL3359627)Show InChI InChI=1S/C12H8ClNO2S/c13-11-8-9(14(15)16)6-7-12(11)17-10-4-2-1-3-5-10/h1-8H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028915
(CHEMBL3359100)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-1-6-11(15(16)17)12(7-8)18-10-4-2-9(14)3-5-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028930
(CHEMBL3359629)Show InChI InChI=1S/C12H9ClN2O3/c13-11-7-9(15(16)17)3-6-12(11)18-10-4-1-8(14)2-5-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028924
(CHEMBL3359110)Show InChI InChI=1S/C12H6BrCl2NO2S/c13-7-3-1-2-4-11(7)19-12-6-9(15)8(14)5-10(12)16(17)18/h1-6H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50028926
(CHEMBL3359624)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-1-6-12(11(7-8)15(16)17)18-10-4-2-9(14)3-5-10/h1-7H,14H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50028887
(CHEMBL3359635)Show InChI InChI=1S/C11H7ClN2O2S/c12-8-1-2-11(10(7-8)14(15)16)17-9-3-5-13-6-4-9/h1-7H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028922
(CHEMBL3359108)Show InChI InChI=1S/C12H9ClN2O2S/c13-11-7-9(15(16)17)4-5-12(11)18-10-3-1-2-8(14)6-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028929
(CHEMBL3359628)Show InChI InChI=1S/C12H9ClN2O3/c13-8-1-6-12(11(7-8)15(16)17)18-10-4-2-9(14)3-5-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028934
(CHEMBL1412666)Show InChI InChI=1S/C11H7ClN2O2S/c12-8-4-5-10(9(7-8)14(15)16)17-11-3-1-2-6-13-11/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028937
(CHEMBL3359636)Show InChI InChI=1S/C13H10N2O3S/c1-9(16)10-2-3-13(12(8-10)15(17)18)19-11-4-6-14-7-5-11/h2-8H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028900
(CHEMBL3359099)Show InChI InChI=1S/C12H9ClN2O2S/c13-11-7-9(15(16)17)3-6-12(11)18-10-4-1-8(14)2-5-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028890
(CHEMBL3359651)Show InChI InChI=1S/C10H8N2O2S2/c11-7-3-1-2-4-9(7)16-10-8(12(13)14)5-6-15-10/h1-6H,11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50028887
(CHEMBL3359635)Show InChI InChI=1S/C11H7ClN2O2S/c12-8-1-2-11(10(7-8)14(15)16)17-9-3-5-13-6-4-9/h1-7H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028895
(CHEMBL451589)Show InChI InChI=1S/C14H10N2OS/c17-13-11-8-4-5-9-12(11)15-14(18)16(13)10-6-2-1-3-7-10/h1-9H,(H,15,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50385902
(CHEMBL2041596)Show SMILES COc1cc(COC(=O)c2ccc(o2)-c2ccccc2)cc(OC)c1OC Show InChI InChI=1S/C21H20O6/c1-23-18-11-14(12-19(24-2)20(18)25-3)13-26-21(22)17-10-9-16(27-17)15-7-5-4-6-8-15/h4-12H,13H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of PDE7 (unknown origin) |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028931
(CHEMBL3359630)Show InChI InChI=1S/C10H6ClNO2S2/c11-8-6-7(12(13)14)3-4-9(8)16-10-2-1-5-15-10/h1-6H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028919
(CHEMBL3359105)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-5-6-10(15(16)17)12(7-8)18-11-4-2-1-3-9(11)14/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028921
(CHEMBL3359107)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-4-5-12(11(6-8)15(16)17)18-10-3-1-2-9(14)7-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028920
(CHEMBL3359106)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-5-6-12(10(7-8)15(16)17)18-11-4-2-1-3-9(11)14/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028923
(CHEMBL3359109)Show InChI InChI=1S/C12H9FN2O2S/c13-8-1-6-12(11(7-8)15(16)17)18-10-4-2-9(14)3-5-10/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028897
(CHEMBL3359094)Show InChI InChI=1S/C12H8Cl2N2O2S/c13-7-5-10(16(17)18)12(6-8(7)14)19-11-4-2-1-3-9(11)15/h1-6H,15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028938
(CHEMBL3359640)Show InChI InChI=1S/C12H11ClN2S/c13-11-7-9(15)3-6-12(11)16-10-4-1-8(14)2-5-10/h1-7H,14-15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50028886
(CHEMBL3359633)Show InChI InChI=1S/C11H7ClN2O2S/c12-10-7-8(14(15)16)1-2-11(10)17-9-3-5-13-6-4-9/h1-7H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028892
(CHEMBL3359655)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-5-6-9(14)12(7-8)18-11-4-2-1-3-10(11)15(16)17/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50028886
(CHEMBL3359633)Show InChI InChI=1S/C11H7ClN2O2S/c12-10-7-8(14(15)16)1-2-11(10)17-9-3-5-13-6-4-9/h1-7H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028889
(CHEMBL1596470)Show InChI InChI=1S/C12H10N2O2S/c13-9-5-1-3-7-11(9)17-12-8-4-2-6-10(12)14(15)16/h1-8H,13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028933
(CHEMBL1347034)Show InChI InChI=1S/C11H7ClN2O2S/c12-8-4-5-9(14(15)16)10(7-8)17-11-3-1-2-6-13-11/h1-7H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028898
(CHEMBL3359096)Show InChI InChI=1S/C12H9ClN2O2S/c13-9-7-8(15(16)17)5-6-11(9)18-12-4-2-1-3-10(12)14/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028899
(CHEMBL3359098)Show InChI InChI=1S/C13H9F3N2O2S/c14-13(15,16)11-7-9(18(19)20)3-6-12(11)21-10-4-1-8(17)2-5-10/h1-7H,17H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
(Homo sapiens (Human)) | BDBM50028887
(CHEMBL3359635)Show InChI InChI=1S/C11H7ClN2O2S/c12-8-1-2-11(10(7-8)14(15)16)17-9-3-5-13-6-4-9/h1-7H | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Homo sapiens (Human)) | BDBM50028891
(CHEMBL3359653)Show InChI InChI=1S/C12H9ClN2O2S/c13-8-5-6-11(9(14)7-8)18-12-4-2-1-3-10(12)15(16)17/h1-7H,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.24E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC)
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay |
J Med Chem 57: 8590-607 (2014)
Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC |
More data for this Ligand-Target Pair | |