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PubMed code 25379609

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032257
PNG
(CHEMBL3352977)
Show SMILES COc1cc2CCN(Cc3ccc(o3)-c3ccc(O)cc3)Cc2cc1OC
Show InChI InChI=1S/C22H23NO4/c1-25-21-11-16-9-10-23(13-17(16)12-22(21)26-2)14-19-7-8-20(27-19)15-3-5-18(24)6-4-15/h3-8,11-12,24H,9-10,13-14H2,1-2H3
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n/an/an/an/a 8.10E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50429195
PNG
(CHEMBL260505)
Show SMILES COc1cc2CCN(Cc3ccc(cc3)-c3ccc(O)cc3)Cc2cc1OC
Show InChI InChI=1S/C24H25NO3/c1-27-23-13-20-11-12-25(16-21(20)14-24(23)28-2)15-17-3-5-18(6-4-17)19-7-9-22(26)10-8-19/h3-10,13-14,26H,11-12,15-16H2,1-2H3
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n/an/an/an/a 9.30E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032249
PNG
(CHEMBL3352986)
Show SMILES COc1ccc(cc1)-c1ccc(OCCCCN2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C28H33NO4/c1-30-25-10-6-21(7-11-25)22-8-12-26(13-9-22)33-17-5-4-15-29-16-14-23-18-27(31-2)28(32-3)19-24(23)20-29/h6-13,18-19H,4-5,14-17,20H2,1-3H3
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n/an/an/an/a 4n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032252
PNG
(CHEMBL3352982)
Show SMILES COc1ccc(cc1)-c1ccc(OCCCN2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C27H31NO4/c1-29-24-9-5-20(6-10-24)21-7-11-25(12-8-21)32-16-4-14-28-15-13-22-17-26(30-2)27(31-3)18-23(22)19-28/h5-12,17-18H,4,13-16,19H2,1-3H3
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Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032258
PNG
(CHEMBL3352976)
Show SMILES COc1ccc(cc1)-c1ccc(CN2CCc3cc(OC)c(OC)cc3C2)o1
Show InChI InChI=1S/C23H25NO4/c1-25-19-6-4-16(5-7-19)21-9-8-20(28-21)15-24-11-10-17-12-22(26-2)23(27-3)13-18(17)14-24/h4-9,12-13H,10-11,14-15H2,1-3H3
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Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50032256
PNG
(CHEMBL3352978)
Show SMILES COc1ccc(cc1)-c1ccc(CC(=O)N2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C26H27NO4/c1-29-23-10-8-20(9-11-23)19-6-4-18(5-7-19)14-26(28)27-13-12-21-15-24(30-2)25(31-3)16-22(21)17-27/h4-11,15-16H,12-14,17H2,1-3H3
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n/an/an/an/a 1.00E+4n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032260
PNG
(CHEMBL3352974)
Show SMILES COc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2cc(OC)c(OC)cc2C1
Show InChI InChI=1S/C23H23NO5/c1-26-18-6-4-15(5-7-18)19-8-9-20(29-19)23(25)24-11-10-16-12-21(27-2)22(28-3)13-17(16)14-24/h4-9,12-13H,10-11,14H2,1-3H3
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n/an/an/an/a 910n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50353279
PNG
(CHEMBL1830683 | CHEMBL259582)
Show SMILES COc1cc2CCN(CCCC3CCCc4c(OC)cccc34)Cc2cc1OC
Show InChI InChI=1S/C25H33NO3/c1-27-23-11-5-9-21-18(7-4-10-22(21)23)8-6-13-26-14-12-19-15-24(28-2)25(29-3)16-20(19)17-26/h5,9,11,15-16,18H,4,6-8,10,12-14,17H2,1-3H3
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n/an/an/an/a 6.35E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032254
PNG
(CHEMBL3352980)
Show SMILES COc1cc2CCN(CCc3ccc(cc3)-c3ccc(F)cc3)Cc2cc1OC
Show InChI InChI=1S/C25H26FNO2/c1-28-24-15-21-12-14-27(17-22(21)16-25(24)29-2)13-11-18-3-5-19(6-4-18)20-7-9-23(26)10-8-20/h3-10,15-16H,11-14,17H2,1-2H3
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n/an/an/an/a 2.00E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032255
PNG
(CHEMBL3352979)
Show SMILES COc1ccc(cc1)-c1ccc(CCN2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C26H29NO3/c1-28-24-10-8-21(9-11-24)20-6-4-19(5-7-20)12-14-27-15-13-22-16-25(29-2)26(30-3)17-23(22)18-27/h4-11,16-17H,12-15,18H2,1-3H3
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n/an/an/an/a 570n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032262
PNG
(CHEMBL3352988)
Show SMILES COc1cc2CCN(CCc3ccccc3-c3cccc(O)c3)Cc2cc1OC
Show InChI InChI=1S/C25H27NO3/c1-28-24-15-19-11-13-26(17-21(19)16-25(24)29-2)12-10-18-6-3-4-9-23(18)20-7-5-8-22(27)14-20/h3-9,14-16,27H,10-13,17H2,1-2H3
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n/an/an/an/a 230n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032265
PNG
(CHEMBL3352987)
Show SMILES COc1ccc(cc1)-c1ccc2OCC(CCN3CCc4cc(OC)c(OC)cc4C3)=Cc2c1 |c:33|
Show InChI InChI=1S/C29H31NO4/c1-31-26-7-4-21(5-8-26)22-6-9-27-24(15-22)14-20(19-34-27)10-12-30-13-11-23-16-28(32-2)29(33-3)17-25(23)18-30/h4-9,14-17H,10-13,18-19H2,1-3H3
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n/an/an/an/a 1.20E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50429663
PNG
(CHEMBL260506)
Show SMILES COc1ccc(cc1)-c1ccc(CN2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C25H27NO3/c1-27-23-10-8-20(9-11-23)19-6-4-18(5-7-19)16-26-13-12-21-14-24(28-2)25(29-3)15-22(21)17-26/h4-11,14-15H,12-13,16-17H2,1-3H3
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n/an/an/an/a 600n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50429195
PNG
(CHEMBL260505)
Show SMILES COc1cc2CCN(Cc3ccc(cc3)-c3ccc(O)cc3)Cc2cc1OC
Show InChI InChI=1S/C24H25NO3/c1-27-23-13-20-11-12-25(16-21(20)14-24(23)28-2)15-17-3-5-18(6-4-17)19-7-9-22(26)10-8-19/h3-10,13-14,26H,11-12,15-16H2,1-2H3
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n/an/an/an/a 9.30E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032259
PNG
(CHEMBL3352975)
Show SMILES COc1cc2CCN(Cc2cc1OC)C(=O)c1ccc(o1)-c1ccc(O)cc1
Show InChI InChI=1S/C22H21NO5/c1-26-20-11-15-9-10-23(13-16(15)12-21(20)27-2)22(25)19-8-7-18(28-19)14-3-5-17(24)6-4-14/h3-8,11-12,24H,9-10,13H2,1-2H3
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n/an/an/an/a 6.40E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032261
PNG
(CHEMBL3352989)
Show SMILES COc1cccc(c1)-c1ccccc1CCN1CCc2cc(OC)c(OC)cc2C1
Show InChI InChI=1S/C26H29NO3/c1-28-23-9-6-8-21(15-23)24-10-5-4-7-19(24)11-13-27-14-12-20-16-25(29-2)26(30-3)17-22(20)18-27/h4-10,15-17H,11-14,18H2,1-3H3
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n/an/an/an/a 69n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032263
PNG
(CHEMBL3352973)
Show SMILES COc1ccc(cc1)-c1ccc2OCC(CC(=O)N3CCc4cc(OC)c(OC)cc4C3)=Cc2c1 |c:34|
Show InChI InChI=1S/C29H29NO5/c1-32-25-7-4-20(5-8-25)21-6-9-26-23(14-21)12-19(18-35-26)13-29(31)30-11-10-22-15-27(33-2)28(34-3)16-24(22)17-30/h4-9,12,14-16H,10-11,13,17-18H2,1-3H3
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n/an/an/an/a 5.80E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50374731
PNG
(CHEMBL260599)
Show SMILES COc1cc2CCN(CC\C=C3/CCCc4c(OC)cccc34)Cc2cc1OC
Show InChI InChI=1S/C25H31NO3/c1-27-23-11-5-9-21-18(7-4-10-22(21)23)8-6-13-26-14-12-19-15-24(28-2)25(29-3)16-20(19)17-26/h5,8-9,11,15-16H,4,6-7,10,12-14,17H2,1-3H3/b18-8+
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n/an/an/an/a 1.50E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032253
PNG
(CHEMBL3352981)
Show SMILES COc1cc2CCN(Cc3ccc(cc3)-c3ccc(F)cc3)Cc2cc1OC
Show InChI InChI=1S/C24H24FNO2/c1-27-23-13-20-11-12-26(16-21(20)14-24(23)28-2)15-17-3-5-18(6-4-17)19-7-9-22(25)10-8-19/h3-10,13-14H,11-12,15-16H2,1-2H3
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n/an/an/an/a 4.90E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032256
PNG
(CHEMBL3352978)
Show SMILES COc1ccc(cc1)-c1ccc(CC(=O)N2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C26H27NO4/c1-29-23-10-8-20(9-11-23)19-6-4-18(5-7-19)14-26(28)27-13-12-21-15-24(30-2)25(31-3)16-22(21)17-27/h4-11,15-16H,12-14,17H2,1-3H3
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n/an/an/an/a 800n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50032261
PNG
(CHEMBL3352989)
Show SMILES COc1cccc(c1)-c1ccccc1CCN1CCc2cc(OC)c(OC)cc2C1
Show InChI InChI=1S/C26H29NO3/c1-28-23-9-6-8-21(15-23)24-10-5-4-7-19(24)11-13-27-14-12-20-16-25(29-2)26(30-3)17-22(20)18-27/h4-10,15-17H,11-14,18H2,1-3H3
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n/an/an/an/a 2.30E+4n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032250
PNG
(CHEMBL3352984)
Show SMILES COc1ccc(cc1)-c1ccc(NCCCN2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C27H32N2O3/c1-30-25-11-7-21(8-12-25)20-5-9-24(10-6-20)28-14-4-15-29-16-13-22-17-26(31-2)27(32-3)18-23(22)19-29/h5-12,17-18,28H,4,13-16,19H2,1-3H3
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n/an/an/an/a 1.80E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50032251
PNG
(CHEMBL3352983)
Show SMILES COc1ccc(cc1)-c1ccc(OCCN2CCc3cc(OC)c(OC)cc3C2)cc1
Show InChI InChI=1S/C26H29NO4/c1-28-23-8-4-19(5-9-23)20-6-10-24(11-7-20)31-15-14-27-13-12-21-16-25(29-2)26(30-3)17-22(21)18-27/h4-11,16-17H,12-15,18H2,1-3H3
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n/an/an/an/a 930n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50374731
PNG
(CHEMBL260599)
Show SMILES COc1cc2CCN(CC\C=C3/CCCc4c(OC)cccc34)Cc2cc1OC
Show InChI InChI=1S/C25H31NO3/c1-27-23-11-5-9-21-18(7-4-10-22(21)23)8-6-13-26-14-12-19-15-24(28-2)25(29-3)16-20(19)17-26/h5,8-9,11,15-16H,4,6-7,10,12-14,17H2,1-3H3/b18-8+
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n/an/an/an/a 2.80E+3n/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Inhibition of MRP1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...

J Med Chem 57: 9983-94 (2014)


Article DOI: 10.1021/jm501640e
BindingDB Entry DOI: 10.7270/Q2K9394N
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%