Affinity Data by PubMed id=2542555

PubMed code 2542555

Found 74 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50344263 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12N[C@H](Cc3ccccc13)c1ccccc21 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50004107 (1-(1-Thiophen-2-yl-cyclohexyl)-piperidine \| CHEMBL...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017030 (3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-me...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride \| M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50004107 (1-(1-Thiophen-2-yl-cyclohexyl)-piperidine \| CHEMBL...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline \| 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride \| M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017030 (3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-me...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017028 (8-(2-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES COc1ccccc1-c1cccc2CCNCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline \| 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017033 (2-Ethyl-1-phenyl-1,2,3,4-tetrahydro-isoquinoline \|...) Show SMILES CCN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017036 (2-Allyl-1-phenyl-1,2,3,4-tetrahydro-isoquinoline \|...) Show SMILES C=CCN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017025 (2-Allyl-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES CC1Cc2ccccc2C(C)N1CC=C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50344263 ((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...) Show SMILES C[C@]12N[C@H](Cc3ccccc13)c1ccccc21 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017028 (8-(2-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES COc1ccccc1-c1cccc2CCNCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017039 (1-(4-Fluoro-phenyl)-1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Fc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017035 (1-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1Cc2ccccc2C(N1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017035 (1-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1Cc2ccccc2C(N1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017043 (1-(4-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES COc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017036 (2-Allyl-1-phenyl-1,2,3,4-tetrahydro-isoquinoline \|...) Show SMILES C=CCN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017027 (1-Isopropyl-1,2,3,4-tetrahydro-isoquinoline \| CHEM...) Show SMILES CC(C)C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017043 (1-(4-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES COc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017032 (2,3-Dimethyl-1,2,3,4-tetrahydro-isoquinoline \| CHE...) Show SMILES CC1Cc2ccccc2CN1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017040 (3-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1NC(Cc2ccccc12)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017045 (8-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1Cc2cccc(c2CN1)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50014651 (2-Methyl-1,2,3,4-tetrahydro-isoquinoline \| 2-Methy...) Show SMILES CN1CCc2ccccc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017054 (2-Methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinoline ...) Show SMILES CN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017056 (2-Allyl-1-cyclohexyl-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES C=CCN1CCc2ccccc2C1C1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017052 (2-Benzyl-3-methyl-1,2,3,4-tetrahydro-isoquinoline ...) Show SMILES CC1Cc2ccccc2CN1Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017038 (1-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Clc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017033 (2-Ethyl-1-phenyl-1,2,3,4-tetrahydro-isoquinoline \|...) Show SMILES CCN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017055 (1-Thiophen-2-yl-1,2,3,4-tetrahydro-isoquinoline \| ...) Show SMILES C1Cc2ccccc2C(N1)c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017050 (7-Isopropyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridi...) Show SMILES CC(C)C1NCCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017040 (3-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1NC(Cc2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017044 (4-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1NCc2ccccc2C1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017045 (8-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1Cc2cccc(c2CN1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017039 (1-(4-Fluoro-phenyl)-1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Fc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017047 (1-Isobutyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMB...) Show SMILES CC(C)CC1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017051 (6-Allyl-7-isopropyl-4,5,6,7-tetrahydro-thieno[2,3-...) Show SMILES CC(C)C1N(CC=C)CCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017038 (1-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-isoquinolin...) Show SMILES Clc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017023 (2-(2-Ethoxy-ethyl)-1-phenyl-1,2,3,4-tetrahydro-iso...) Show SMILES CCOCCN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017025 (2-Allyl-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES CC1Cc2ccccc2C(C)N1CC=C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017037 (1-p-Tolyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL...) Show SMILES Cc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017056 (2-Allyl-1-cyclohexyl-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES C=CCN1CCc2ccccc2C1C1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017042 (7-Phenyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine ...) Show SMILES C1Cc2ccsc2C(N1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017055 (1-Thiophen-2-yl-1,2,3,4-tetrahydro-isoquinoline \| ...) Show SMILES C1Cc2ccccc2C(N1)c1cccs1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017029 (2-Benzyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C(N1CCc2ccccc2C1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017034 (7-Isopropyl-6-methyl-4,5,6,7-tetrahydro-thieno[2,3...) Show SMILES CC(C)C1N(C)CCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017023 (2-(2-Ethoxy-ethyl)-1-phenyl-1,2,3,4-tetrahydro-iso...) Show SMILES CCOCCN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017051 (6-Allyl-7-isopropyl-4,5,6,7-tetrahydro-thieno[2,3-...) Show SMILES CC(C)C1N(CC=C)CCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017042 (7-Phenyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine ...) Show SMILES C1Cc2ccsc2C(N1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017037 (1-p-Tolyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL...) Show SMILES Cc1ccc(cc1)C1NCCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017024 (1-Naphthalen-2-yl-1,2,3,4-tetrahydro-isoquinoline ...) Show SMILES C1Cc2ccccc2C(N1)c1ccc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017049 (1-Cyclohexyl-1,2,3,4-tetrahydro-isoquinoline \| 1-c...) Show SMILES C1CCC(CC1)C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017053 (7-Methyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine ...) Show SMILES CC1NCCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017027 (1-Isopropyl-1,2,3,4-tetrahydro-isoquinoline \| CHEM...) Show SMILES CC(C)C1NCCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017031 (2-Allyl-1-naphthalen-2-yl-1,2,3,4-tetrahydro-isoqu...) Show SMILES C=CCN1CCc2ccccc2C1c1ccc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017049 (1-Cyclohexyl-1,2,3,4-tetrahydro-isoquinoline \| 1-c...) Show SMILES C1CCC(CC1)C1NCCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017057 (6-Ethyl-7-isopropyl-4,5,6,7-tetrahydro-thieno[2,3-...) Show SMILES CCN1CCc2ccsc2C1C(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017022 (1,3-Dimethyl-1,2,3,4-tetrahydro-isoquinoline \| CHE...) Show SMILES CC1Cc2ccccc2C(C)N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017050 (7-Isopropyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridi...) Show SMILES CC(C)C1NCCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017034 (7-Isopropyl-6-methyl-4,5,6,7-tetrahydro-thieno[2,3...) Show SMILES CC(C)C1N(C)CCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017046 (6-Allyl-7-phenyl-4,5,6,7-tetrahydro-thieno[2,3-c]p...) Show SMILES C=CCN1CCc2ccsc2C1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017047 (1-Isobutyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMB...) Show SMILES CC(C)CC1NCCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017054 (2-Methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinoline ...) Show SMILES CN1CCc2ccccc2C1c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017052 (2-Benzyl-3-methyl-1,2,3,4-tetrahydro-isoquinoline ...) Show SMILES CC1Cc2ccccc2CN1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017032 (2,3-Dimethyl-1,2,3,4-tetrahydro-isoquinoline \| CHE...) Show SMILES CC1Cc2ccccc2CN1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50014651 (2-Methyl-1,2,3,4-tetrahydro-isoquinoline \| 2-Methy...) Show SMILES CN1CCc2ccccc2C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017024 (1-Naphthalen-2-yl-1,2,3,4-tetrahydro-isoquinoline ...) Show SMILES C1Cc2ccccc2C(N1)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017022 (1,3-Dimethyl-1,2,3,4-tetrahydro-isoquinoline \| CHE...) Show SMILES CC1Cc2ccccc2C(C)N1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50017053 (7-Methyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine ...) Show SMILES CC1NCCc2ccsc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017026 (1-Phenyl-2,3-dihydro-1H-isoindole \| CHEMBL21672) Show SMILES C1NC(c2ccccc12)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017026 (1-Phenyl-2,3-dihydro-1H-isoindole \| CHEMBL21672) Show SMILES C1NC(c2ccccc12)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50017044 (4-Phenyl-1,2,3,4-tetrahydro-isoquinoline \| CHEMBL2...) Show SMILES C1NCc2ccccc2C1c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
G. D. Searle& Co. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%