Found 34 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088564
(CHEMBL3577041)Show SMILES COC(=O)[C@@H](NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1)C(C)C |r| Show InChI InChI=1S/C23H25N3O6/c1-13(2)19(23(31)32-4)26-21(29)15-9-11-16(12-10-15)25-22(30)20(28)17-7-5-6-8-18(17)24-14(3)27/h5-13,19H,1-4H3,(H,24,27)(H,25,30)(H,26,29)/t19-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM15581
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088560
(CHEMBL3577045)Show SMILES COC(=O)CCNC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C21H21N3O6/c1-13(25)23-17-6-4-3-5-16(17)19(27)21(29)24-15-9-7-14(8-10-15)20(28)22-12-11-18(26)30-2/h3-10H,11-12H2,1-2H3,(H,22,28)(H,23,25)(H,24,29) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088568
(CHEMBL3577037)Show InChI InChI=1S/C14H16N2O5/c1-9(17)16-11-6-4-3-5-10(11)13(19)14(20)15-8-7-12(18)21-2/h3-6H,7-8H2,1-2H3,(H,15,20)(H,16,17) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088563
(CHEMBL3577042)Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 |r| Show InChI InChI=1S/C27H25N3O6/c1-17(31)28-22-11-7-6-10-21(22)24(32)26(34)29-20-14-12-19(13-15-20)25(33)30-23(27(35)36-2)16-18-8-4-3-5-9-18/h3-15,23H,16H2,1-2H3,(H,28,31)(H,29,34)(H,30,33)/t23-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088565
(CHEMBL3577040)Show SMILES COC(=O)[C@H](C)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 |r| Show InChI InChI=1S/C21H21N3O6/c1-12(21(29)30-3)22-19(27)14-8-10-15(11-9-14)24-20(28)18(26)16-6-4-5-7-17(16)23-13(2)25/h4-12H,1-3H3,(H,22,27)(H,23,25)(H,24,28)/t12-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088562
(CHEMBL3577043)Show SMILES COC(=O)C(C)(C)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C22H23N3O6/c1-13(26)23-17-8-6-5-7-16(17)18(27)20(29)24-15-11-9-14(10-12-15)19(28)25-22(2,3)21(30)31-4/h5-12H,1-4H3,(H,23,26)(H,24,29)(H,25,28) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088557
(CHEMBL3577048)Show SMILES COC(=O)C1(CCCC1)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C24H25N3O6/c1-15(28)25-19-8-4-3-7-18(19)20(29)22(31)26-17-11-9-16(10-12-17)21(30)27-24(23(32)33-2)13-5-6-14-24/h3-4,7-12H,5-6,13-14H2,1-2H3,(H,25,28)(H,26,31)(H,27,30) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088559
(CHEMBL3577046)Show SMILES COC(=O)CCCNC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C22H23N3O6/c1-14(26)24-18-7-4-3-6-17(18)20(28)22(30)25-16-11-9-15(10-12-16)21(29)23-13-5-8-19(27)31-2/h3-4,6-7,9-12H,5,8,13H2,1-2H3,(H,23,29)(H,24,26)(H,25,30) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM22787
(1-acetyl-2,3-dihydro-1H-indole-2,3-dione | Acetyli...)Show InChI InChI=1S/C10H7NO3/c1-6(12)11-8-5-3-2-4-7(8)9(13)10(11)14/h2-5H,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088554
(CHEMBL3577036)Show SMILES COC(=O)C[C@H](NC(=O)C(=O)c1ccccc1NC(C)=O)C(=O)OC |r| Show InChI InChI=1S/C16H18N2O7/c1-9(19)17-11-7-5-4-6-10(11)14(21)15(22)18-12(16(23)25-3)8-13(20)24-2/h4-7,12H,8H2,1-3H3,(H,17,19)(H,18,22)/t12-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088561
(CHEMBL3577044)Show SMILES COC(=O)C[C@H](NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1)C(=O)OC |r| Show InChI InChI=1S/C23H23N3O8/c1-13(27)24-17-7-5-4-6-16(17)20(29)22(31)25-15-10-8-14(9-11-15)21(30)26-18(23(32)34-3)12-19(28)33-2/h4-11,18H,12H2,1-3H3,(H,24,27)(H,25,31)(H,26,30)/t18-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088567
(CHEMBL3577038)Show InChI InChI=1S/C15H18N2O5/c1-10(18)17-12-7-4-3-6-11(12)14(20)15(21)16-9-5-8-13(19)22-2/h3-4,6-7H,5,8-9H2,1-2H3,(H,16,21)(H,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088566
(CHEMBL3577039)Show InChI InChI=1S/C17H22N2O5/c1-12(20)19-14-9-6-5-8-13(14)16(22)17(23)18-11-7-3-4-10-15(21)24-2/h5-6,8-9H,3-4,7,10-11H2,1-2H3,(H,18,23)(H,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088555
(CHEMBL3577035)Show SMILES COC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1ccccc1NC(C)=O |r| Show InChI InChI=1S/C17H22N2O5/c1-10(2)9-14(17(23)24-4)19-16(22)15(21)12-7-5-6-8-13(12)18-11(3)20/h5-8,10,14H,9H2,1-4H3,(H,18,20)(H,19,22)/t14-/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088556
(CHEMBL3577034)Show SMILES CCOC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C19H18N2O5/c1-3-26-19(25)13-8-10-14(11-9-13)21-18(24)17(23)15-6-4-5-7-16(15)20-12(2)22/h4-11H,3H2,1-2H3,(H,20,22)(H,21,24) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM15581
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088563
(CHEMBL3577042)Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 |r| Show InChI InChI=1S/C27H25N3O6/c1-17(31)28-22-11-7-6-10-21(22)24(32)26(34)29-20-14-12-19(13-15-20)25(33)30-23(27(35)36-2)16-18-8-4-3-5-9-18/h3-15,23H,16H2,1-2H3,(H,28,31)(H,29,34)(H,30,33)/t23-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088562
(CHEMBL3577043)Show SMILES COC(=O)C(C)(C)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C22H23N3O6/c1-13(26)23-17-8-6-5-7-16(17)18(27)20(29)24-15-11-9-14(10-12-15)19(28)25-22(2,3)21(30)31-4/h5-12H,1-4H3,(H,23,26)(H,24,29)(H,25,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088557
(CHEMBL3577048)Show SMILES COC(=O)C1(CCCC1)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C24H25N3O6/c1-15(28)25-19-8-4-3-7-18(19)20(29)22(31)26-17-11-9-16(10-12-17)21(30)27-24(23(32)33-2)13-5-6-14-24/h3-4,7-12H,5-6,13-14H2,1-2H3,(H,25,28)(H,26,31)(H,27,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM22787
(1-acetyl-2,3-dihydro-1H-indole-2,3-dione | Acetyli...)Show InChI InChI=1S/C10H7NO3/c1-6(12)11-8-5-3-2-4-7(8)9(13)10(11)14/h2-5H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088564
(CHEMBL3577041)Show SMILES COC(=O)[C@@H](NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1)C(C)C |r| Show InChI InChI=1S/C23H25N3O6/c1-13(2)19(23(31)32-4)26-21(29)15-9-11-16(12-10-15)25-22(30)20(28)17-7-5-6-8-18(17)24-14(3)27/h5-13,19H,1-4H3,(H,24,27)(H,25,30)(H,26,29)/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088554
(CHEMBL3577036)Show SMILES COC(=O)C[C@H](NC(=O)C(=O)c1ccccc1NC(C)=O)C(=O)OC |r| Show InChI InChI=1S/C16H18N2O7/c1-9(19)17-11-7-5-4-6-10(11)14(21)15(22)18-12(16(23)25-3)8-13(20)24-2/h4-7,12H,8H2,1-3H3,(H,17,19)(H,18,22)/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.59E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088555
(CHEMBL3577035)Show SMILES COC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1ccccc1NC(C)=O |r| Show InChI InChI=1S/C17H22N2O5/c1-10(2)9-14(17(23)24-4)19-16(22)15(21)12-7-5-6-8-13(12)18-11(3)20/h5-8,10,14H,9H2,1-4H3,(H,18,20)(H,19,22)/t14-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088560
(CHEMBL3577045)Show SMILES COC(=O)CCNC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C21H21N3O6/c1-13(25)23-17-6-4-3-5-16(17)19(27)21(29)24-15-9-7-14(8-10-15)20(28)22-12-11-18(26)30-2/h3-10H,11-12H2,1-2H3,(H,22,28)(H,23,25)(H,24,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088559
(CHEMBL3577046)Show SMILES COC(=O)CCCNC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C22H23N3O6/c1-14(26)24-18-7-4-3-6-17(18)20(28)22(30)25-16-11-9-15(10-12-16)21(29)23-13-5-8-19(27)31-2/h3-4,6-7,9-12H,5,8,13H2,1-2H3,(H,23,29)(H,24,26)(H,25,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088566
(CHEMBL3577039)Show InChI InChI=1S/C17H22N2O5/c1-12(20)19-14-9-6-5-8-13(14)16(22)17(23)18-11-7-3-4-10-15(21)24-2/h5-6,8-9H,3-4,7,10-11H2,1-2H3,(H,18,23)(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088565
(CHEMBL3577040)Show SMILES COC(=O)[C@H](C)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 |r| Show InChI InChI=1S/C21H21N3O6/c1-12(21(29)30-3)22-19(27)14-8-10-15(11-9-14)24-20(28)18(26)16-6-4-5-7-17(16)23-13(2)25/h4-12H,1-3H3,(H,22,27)(H,23,25)(H,24,28)/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088558
(CHEMBL3577047)Show SMILES COC(=O)CCCCCNC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C24H27N3O6/c1-16(28)26-20-9-6-5-8-19(20)22(30)24(32)27-18-13-11-17(12-14-18)23(31)25-15-7-3-4-10-21(29)33-2/h5-6,8-9,11-14H,3-4,7,10,15H2,1-2H3,(H,25,31)(H,26,28)(H,27,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088561
(CHEMBL3577044)Show SMILES COC(=O)C[C@H](NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1)C(=O)OC |r| Show InChI InChI=1S/C23H23N3O8/c1-13(27)24-17-7-5-4-6-16(17)20(29)22(31)25-15-10-8-14(9-11-15)21(30)26-18(23(32)34-3)12-19(28)33-2/h4-11,18H,12H2,1-3H3,(H,24,27)(H,25,31)(H,26,30)/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat)) | BDBM50088558
(CHEMBL3577047)Show SMILES COC(=O)CCCCCNC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C24H27N3O6/c1-16(28)26-20-9-6-5-8-19(20)22(30)24(32)27-18-13-11-17(12-14-18)23(31)25-15-7-3-4-10-21(29)33-2/h5-6,8-9,11-14H,3-4,7,10,15H2,1-2H3,(H,25,31)(H,26,28)(H,27,32) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088567
(CHEMBL3577038)Show InChI InChI=1S/C15H18N2O5/c1-10(18)17-12-7-4-3-6-11(12)14(20)15(21)16-9-5-8-13(19)22-2/h3-4,6-7H,5,8-9H2,1-2H3,(H,16,21)(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088556
(CHEMBL3577034)Show SMILES CCOC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 Show InChI InChI=1S/C19H18N2O5/c1-3-26-19(25)13-8-10-14(11-9-13)21-18(24)17(23)15-6-4-5-7-16(15)20-12(2)22/h4-11H,3H2,1-2H3,(H,20,22)(H,21,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Bos taurus) | BDBM50088568
(CHEMBL3577037)Show InChI InChI=1S/C14H16N2O5/c1-9(17)16-11-6-4-3-5-10(11)13(19)14(20)15-8-7-12(18)21-2/h3-6H,7-8H2,1-2H3,(H,15,20)(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate |
Bioorg Med Chem Lett 25: 70-4 (2015)
Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH |
More data for this Ligand-Target Pair | |