Affinity Data by PubMed id=25529738

PubMed code 25529738

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50042034 ((5Z)-7-Oxozeaenol \| 5Z-7-Oxozeaenol \| CHEBI:67559 ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of MAP2K1 (unknown origin) using unphosphorylated GST-tagged ERK2 substrate protein assessed as phosphorylation by ELISA				Bioorg Med Chem Lett 25: 593-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.011 BindingDB Entry DOI: 10.7270/Q28W3FXP
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 (Homo sapiens (Human))	BDBM50042034 ((5Z)-7-Oxozeaenol \| 5Z-7-Oxozeaenol \| CHEBI:67559 ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of TAK1 (unknown origin) using unphosphorylated GST-tagged MAP2K7 substrate protein assessed as phosphorylation by ELISA				Bioorg Med Chem Lett 25: 593-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.011 BindingDB Entry DOI: 10.7270/Q28W3FXP
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dual specificity mitogen-activated protein kinase kinase 7 (Homo sapiens (Human))	BDBM50042034 ((5Z)-7-Oxozeaenol \| 5Z-7-Oxozeaenol \| CHEBI:67559 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of MAP2K7 (unknown origin) using unphosphorylated GST-tagged JNK1 substrate protein assessed as phosphorylation by ELISA				Bioorg Med Chem Lett 25: 593-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.011 BindingDB Entry DOI: 10.7270/Q28W3FXP
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50042034 ((5Z)-7-Oxozeaenol \| 5Z-7-Oxozeaenol \| CHEBI:67559 ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Osaka Prefecture University Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin) using FITC-labeled substrate peptide assessed as phosphorylation				Bioorg Med Chem Lett 25: 593-6 (2015) Article DOI: 10.1016/j.bmcl.2014.12.011 BindingDB Entry DOI: 10.7270/Q28W3FXP
Osaka Prefecture University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%