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PubMed code 25532755

Compile data set for download or QSAR
Found 46 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063895
PNG
(CHEMBL3403631)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCOC(CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1/C24H23ClN2O5/c1-14(2)32-20-6-3-15(9-16(20)12-26)13-31-17-4-5-19-18(10-17)23(25)24-21(11-22(28)29)30-8-7-27(19)24/h3-6,9-10,14,21H,7-8,11,13H2,1-2H3,(H,28,29)
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n/an/a 0.0100n/an/an/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063895
PNG
(CHEMBL3403631)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCOC(CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1/C24H23ClN2O5/c1-14(2)32-20-6-3-15(9-16(20)12-26)13-31-17-4-5-19-18(10-17)23(25)24-21(11-22(28)29)30-8-7-27(19)24/h3-6,9-10,14,21H,7-8,11,13H2,1-2H3,(H,28,29)
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n/an/a 0.230n/an/an/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063873
PNG
(CHEMBL3400912)
Show SMILES CS(=O)(=O)c1ccc(COc2ccc3[nH]c4C(CC(O)=O)NCCc4c3c2)cc1
Show InChI InChI=1/C21H22N2O5S/c1-29(26,27)15-5-2-13(3-6-15)12-28-14-4-7-18-17(10-14)16-8-9-22-19(11-20(24)25)21(16)23-18/h2-7,10,19,22-23H,8-9,11-12H2,1H3,(H,24,25)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063888
PNG
(CHEMBL3403624)
Show SMILES CCOc1ccc(COc2ccc3n4CCCC(CC(O)=O)c4cc3c2)cc1OCC
Show InChI InChI=1/C25H29NO5/c1-3-29-23-10-7-17(12-24(23)30-4-2)16-31-20-8-9-21-19(13-20)14-22-18(15-25(27)28)6-5-11-26(21)22/h7-10,12-14,18H,3-6,11,15-16H2,1-2H3,(H,27,28)
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n/an/an/an/a 170n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063891
PNG
(CHEMBL3403627)
Show SMILES OC(=O)CC1OCCn2c1cc1cc(OCc3ccc(OCF)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1/C22H19F4NO5/c23-12-32-19-4-1-13(7-16(19)22(24,25)26)11-31-15-2-3-17-14(8-15)9-18-20(10-21(28)29)30-6-5-27(17)18/h1-4,7-9,20H,5-6,10-12H2,(H,28,29)
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n/an/an/an/a 11n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063898
PNG
(CHEMBL3403634)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCNC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1/C24H25F3N2O4/c1-14(2)33-22-6-3-15(9-18(22)24(25,26)27)13-32-17-4-5-20-16(10-17)11-21-19(12-23(30)31)28-7-8-29(20)21/h3-6,9-11,14,19,28H,7-8,12-13H2,1-2H3,(H,30,31)
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n/an/an/an/a 0.670n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063895
PNG
(CHEMBL3403631)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCOC(CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1/C24H23ClN2O5/c1-14(2)32-20-6-3-15(9-16(20)12-26)13-31-17-4-5-19-18(10-17)23(25)24-21(11-22(28)29)30-8-7-27(19)24/h3-6,9-10,14,21H,7-8,11,13H2,1-2H3,(H,28,29)
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n/an/an/an/a 0.830n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 5.80n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor by beta-arrestin recruitment assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063860
PNG
(CHEMBL3403621)
Show SMILES OC(=O)CC1CCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C27H28F3NO3/c28-27(29,30)23-12-16(8-10-20(23)17-4-1-2-5-17)15-34-19-9-11-24-22(14-19)21-7-3-6-18(13-25(32)33)26(21)31-24/h8-12,14,17-18,31H,1-7,13,15H2,(H,32,33)
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n/an/an/an/a 1.40n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063874
PNG
(CHEMBL3400911)
Show SMILES CC(C)(C)c1ccc(COc2ccc3[nH]c4C(CC(O)=O)NCCc4c3c2)cc1
Show InChI InChI=1/C24H28N2O3/c1-24(2,3)16-6-4-15(5-7-16)14-29-17-8-9-20-19(12-17)18-10-11-25-21(13-22(27)28)23(18)26-20/h4-9,12,21,25-26H,10-11,13-14H2,1-3H3,(H,27,28)
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n/an/an/an/a 19n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 0.0300n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 0.0600n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063880
PNG
(CHEMBL3400906)
Show SMILES OC(=O)CC1CCCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1/C27H28F3NO3/c28-27(29,30)23-12-17(7-9-22(23)18-4-1-2-5-18)16-34-21-8-10-24-20(13-21)14-25-19(15-26(32)33)6-3-11-31(24)25/h7-10,12-14,18-19H,1-6,11,15-16H2,(H,32,33)
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n/an/an/an/a 2.30n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063887
PNG
(CHEMBL3403623)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCCC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1/C25H26F3NO4/c1-15(2)33-23-8-5-16(10-20(23)25(26,27)28)14-32-19-6-7-21-18(11-19)12-22-17(13-24(30)31)4-3-9-29(21)22/h5-8,10-12,15,17H,3-4,9,13-14H2,1-2H3,(H,30,31)
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n/an/an/an/a 3.30n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063890
PNG
(CHEMBL3403626)
Show SMILES OC(=O)CC1OCCn2c1cc1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1/C26H26F3NO4/c27-26(28,29)21-11-16(5-7-20(21)17-3-1-2-4-17)15-34-19-6-8-22-18(12-19)13-23-24(14-25(31)32)33-10-9-30(22)23/h5-8,11-13,17,24H,1-4,9-10,14-15H2,(H,31,32)
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n/an/an/an/a 0.140n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063893
PNG
(CHEMBL3403629)
Show SMILES OC(=O)CC1OCCn2c1cc1cc(OCc3ccc(OC(CF)CF)c(Cl)c3)ccc21
Show InChI InChI=1/C23H22ClF2NO5/c24-18-7-14(1-4-21(18)32-17(11-25)12-26)13-31-16-2-3-19-15(8-16)9-20-22(10-23(28)29)30-6-5-27(19)20/h1-4,7-9,17,22H,5-6,10-13H2,(H,28,29)
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n/an/an/an/a 0.480n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063894
PNG
(CHEMBL3403630)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCOC(CC(O)=O)c4c(Cl)c3c2)cc1C(F)(F)F
Show InChI InChI=1/C24H23ClF3NO5/c1-13(2)34-19-6-3-14(9-17(19)24(26,27)28)12-33-15-4-5-18-16(10-15)22(25)23-20(11-21(30)31)32-8-7-29(18)23/h3-6,9-10,13,20H,7-8,11-12H2,1-2H3,(H,30,31)
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n/an/an/an/a 0.0400n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063900
PNG
(CHEMBL3403636)
Show SMILES CN1CCn2c(C1CC(O)=O)c(Cl)c1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1/C27H28ClF3N2O3/c1-32-10-11-33-22-9-7-18(13-20(22)25(28)26(33)23(32)14-24(34)35)36-15-16-6-8-19(17-4-2-3-5-17)21(12-16)27(29,30)31/h6-9,12-13,17,23H,2-5,10-11,14-15H2,1H3,(H,34,35)
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n/an/an/an/a 0.150n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Rattus norvegicus)
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at rat S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063863
PNG
(CHEMBL3403620)
Show SMILES CC1(CC(O)=O)OCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C27H28F3NO4/c1-26(14-24(32)33)25-20(10-11-35-26)21-13-18(7-9-23(21)31-25)34-15-16-6-8-19(17-4-2-3-5-17)22(12-16)27(28,29)30/h6-9,12-13,17,31H,2-5,10-11,14-15H2,1H3,(H,32,33)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063866
PNG
(CHEMBL3403617)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(Cl)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C21H18ClF3N2O3/c22-16-3-1-11(7-15(16)21(23,24)25)10-30-12-2-4-17-14(8-12)13-5-6-26-18(9-19(28)29)20(13)27-17/h1-4,7-8,18,26-27H,5-6,9-10H2,(H,28,29)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063868
PNG
(CHEMBL3400916)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(OC(F)(F)F)c(Cl)c3)cc21
Show InChI InChI=1/C21H18ClF3N2O4/c22-15-7-11(1-4-18(15)31-21(23,24)25)10-30-12-2-3-16-14(8-12)13-5-6-26-17(9-19(28)29)20(13)27-16/h1-4,7-8,17,26-27H,5-6,9-10H2,(H,28,29)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063877
PNG
(CHEMBL3400909)
Show SMILES CC(C)Oc1ccc(COc2ccc3[nH]c4C(CC(O)=O)NCCc4c3c2)cc1C#N
Show InChI InChI=1/C24H25N3O4/c1-14(2)31-22-6-3-15(9-16(22)12-25)13-30-17-4-5-20-19(10-17)18-7-8-26-21(11-23(28)29)24(18)27-20/h3-6,9-10,14,21,26-27H,7-8,11,13H2,1-2H3,(H,28,29)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063889
PNG
(CHEMBL3403625)
Show SMILES OC(=O)CC1OCCn2c1cc1cc(OCc3cc(OC(F)(F)F)cc(c3)C#N)ccc21
Show InChI InChI=1/C22H17F3N2O5/c23-22(24,25)32-17-6-13(11-26)5-14(7-17)12-31-16-1-2-18-15(8-16)9-19-20(10-21(28)29)30-4-3-27(18)19/h1-2,5-9,20H,3-4,10,12H2,(H,28,29)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063897
PNG
(CHEMBL3403633)
Show SMILES CC(C)Cc1ccc(COc2ccc3n4CCNC(CC(O)=O)c4cc3c2)cc1C(F)(F)F
Show InChI InChI=1/C25H27F3N2O3/c1-15(2)9-17-4-3-16(10-20(17)25(26,27)28)14-33-19-5-6-22-18(11-19)12-23-21(13-24(31)32)29-7-8-30(22)23/h3-6,10-12,15,21,29H,7-9,13-14H2,1-2H3,(H,31,32)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063860
PNG
(CHEMBL3403621)
Show SMILES OC(=O)CC1CCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C27H28F3NO3/c28-27(29,30)23-12-16(8-10-20(23)17-4-1-2-5-17)15-34-19-9-11-24-22(14-19)21-7-3-6-18(13-25(32)33)26(21)31-24/h8-12,14,17-18,31H,1-7,13,15H2,(H,32,33)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063865
PNG
(CHEMBL3403618)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3cccc(c3)C(F)(F)F)cc21
Show InChI InChI=1/C21H19F3N2O3/c22-21(23,24)13-3-1-2-12(8-13)11-29-14-4-5-17-16(9-14)15-6-7-25-18(10-19(27)28)20(15)26-17/h1-5,8-9,18,25-26H,6-7,10-11H2,(H,27,28)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063867
PNG
(CHEMBL3400917)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(cc3)C(F)(F)F)cc21
Show InChI InChI=1/C21H19F3N2O3/c22-21(23,24)13-3-1-12(2-4-13)11-29-14-5-6-17-16(9-14)15-7-8-25-18(10-19(27)28)20(15)26-17/h1-6,9,18,25-26H,7-8,10-11H2,(H,27,28)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063872
PNG
(CHEMBL3400913)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3cc(OC(F)(F)F)cc(c3)C#N)cc21
Show InChI InChI=1/C22H18F3N3O4/c23-22(24,25)32-15-6-12(10-26)5-13(7-15)11-31-14-1-2-18-17(8-14)16-3-4-27-19(9-20(29)30)21(16)28-18/h1-2,5-8,19,27-28H,3-4,9,11H2,(H,29,30)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine-1-phosphate receptor 1


(Canis lupus familiaris)
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 0.0400n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at dog S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063862
PNG
(CHEMBL3403622)
Show SMILES OC(=O)CC1OCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H26F3NO4/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-33-23(13-24(31)32)25(19)30-22/h5-8,11-12,16,23,30H,1-4,9-10,13-14H2,(H,31,32)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063863
PNG
(CHEMBL3403620)
Show SMILES CC1(CC(O)=O)OCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C27H28F3NO4/c1-26(14-24(32)33)25-20(10-11-35-26)21-13-18(7-9-23(21)31-25)34-15-16-6-8-19(17-4-2-3-5-17)22(12-16)27(28,29)30/h6-9,12-13,17,31H,2-5,10-11,14-15H2,1H3,(H,32,33)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063896
PNG
(CHEMBL3403632)
Show SMILES OC(=O)CC1OCCn2c1c(Cl)c1cc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)ccc21
Show InChI InChI=1/C26H25ClF3NO4/c27-24-19-12-17(6-8-21(19)31-9-10-34-22(25(24)31)13-23(32)33)35-14-15-5-7-18(16-3-1-2-4-16)20(11-15)26(28,29)30/h5-8,11-12,16,22H,1-4,9-10,13-14H2,(H,32,33)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 1.20n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor by beta-arrestin recruitment assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063878
PNG
(CHEMBL3400908)
Show SMILES OC(=O)CC1CCCn2c1cc1cc(OCc3cc(cc(c3)C(F)(F)F)C(F)(F)F)ccc21
Show InChI InChI=1/C23H19F6NO3/c24-22(25,26)16-6-13(7-17(11-16)23(27,28)29)12-33-18-3-4-19-15(8-18)9-20-14(10-21(31)32)2-1-5-30(19)20/h3-4,6-9,11,14H,1-2,5,10,12H2,(H,31,32)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063879
PNG
(CHEMBL3400907)
Show SMILES OC(=O)CC1CCCn2c1cc1cc(OCc3cc(OC(F)(F)F)cc(c3)C#N)ccc21
Show InChI InChI=1/C23H19F3N2O4/c24-23(25,26)32-19-7-14(12-27)6-15(8-19)13-31-18-3-4-20-17(9-18)10-21-16(11-22(29)30)2-1-5-28(20)21/h3-4,6-10,16H,1-2,5,11,13H2,(H,29,30)
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n/an/an/an/a 25n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063892
PNG
(CHEMBL3403628)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCOC(CC(O)=O)c4cc3c2)cc1C#N
Show InChI InChI=1/C24H24N2O5/c1-15(2)31-22-6-3-16(9-18(22)13-25)14-30-19-4-5-20-17(10-19)11-21-23(12-24(27)28)29-8-7-26(20)21/h3-6,9-11,15,23H,7-8,12,14H2,1-2H3,(H,27,28)
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Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063895
PNG
(CHEMBL3403631)
Show SMILES CC(C)Oc1ccc(COc2ccc3n4CCOC(CC(O)=O)c4c(Cl)c3c2)cc1C#N
Show InChI InChI=1/C24H23ClN2O5/c1-14(2)32-20-6-3-15(9-16(20)12-26)13-31-17-4-5-19-18(10-17)23(25)24-21(11-22(28)29)30-8-7-27(19)24/h3-6,9-10,14,21H,7-8,11,13H2,1-2H3,(H,28,29)
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n/an/an/an/a 0.0400n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063899
PNG
(CHEMBL3403635)
Show SMILES CN1CCn2c(C1CC(O)=O)c(Cl)c1cc(OCc3cc(OC(F)(F)F)cc(c3)C#N)ccc21
Show InChI InChI=1/C23H19ClF3N3O4/c1-29-4-5-30-18-3-2-15(9-17(18)21(24)22(30)19(29)10-20(31)32)33-12-14-6-13(11-28)7-16(8-14)34-23(25,26)27/h2-3,6-9,19H,4-5,10,12H2,1H3,(H,31,32)
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n/an/an/an/a 1.70n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (Human))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor by beta-arrestin recruitment assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor by beta-arrestin recruitment assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063875
PNG
(CHEMBL3400910)
Show SMILES CC(C)Cc1ccc(COc2ccc3[nH]c4C(CC(O)=O)NCCc4c3c2)cc1C(F)(F)F
Show InChI InChI=1/C25H27F3N2O3/c1-14(2)9-16-4-3-15(10-20(16)25(26,27)28)13-33-17-5-6-21-19(11-17)18-7-8-29-22(12-23(31)32)24(18)30-21/h3-6,10-11,14,22,29-30H,7-9,12-13H2,1-2H3,(H,31,32)
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n/an/an/an/a 0.0400n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Mus musculus (Mouse))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 0.0500n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at mouse S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50063864
PNG
(CHEMBL3403619)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(c3)C(F)(F)F)cc21
Show InChI InChI=1/C26H27F3N2O3/c27-26(28,29)21-11-15(5-7-18(21)16-3-1-2-4-16)14-34-17-6-8-22-20(12-17)19-9-10-30-23(13-24(32)33)25(19)31-22/h5-8,11-12,16,23,30-31H,1-4,9-10,13-14H2,(H,32,33)
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n/an/an/an/a 26n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P4 receptor by beta-arrestin recruitment assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063869
PNG
(CHEMBL3400915)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(Cl)c(Cl)c3)cc21
Show InChI InChI=1/C20H18Cl2N2O3/c21-15-3-1-11(7-16(15)22)10-27-12-2-4-17-14(8-12)13-5-6-23-18(9-19(25)26)20(13)24-17/h1-4,7-8,18,23-24H,5-6,9-10H2,(H,25,26)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50063871
PNG
(CHEMBL3400914)
Show SMILES OC(=O)CC1NCCc2c1[nH]c1ccc(OCc3cccc(OC(F)(F)F)c3)cc21
Show InChI InChI=1/C21H19F3N2O4/c22-21(23,24)30-14-3-1-2-12(8-14)11-29-13-4-5-17-16(9-13)15-6-7-25-18(10-19(27)28)20(15)26-17/h1-5,8-9,18,25-26H,6-7,10-11H2,(H,27,28)
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n/an/an/an/a 290n/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assay


Bioorg Med Chem Lett 25: 659-63 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.089
BindingDB Entry DOI: 10.7270/Q25T3N5P
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%