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PubMed code 25559347

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-arginine deiminase type-4


(Mus musculus)		BDBM50071098
PNG
(CHEMBL3409978)
Show SMILES CC(C)(C)n1nnc(n1)[C@H](CCCNC(=N)CCl)NC(=O)c1ccc(cc1)-c1ccccc1 |r|
Show InChI InChI=1S/C24H30ClN7O/c1-24(2,3)32-30-22(29-31-32)20(10-7-15-27-21(26)16-25)28-23(33)19-13-11-18(12-14-19)17-8-5-4-6-9-17/h4-6,8-9,11-14,20H,7,10,15-16H2,1-3H3,(H2,26,27)(H,28,33)/t20-/m0/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 2.00E+4n/an/an/an/a



University of Massachusetts Medical School

Curated by ChEMBL


Assay Description
Inhibition of PAD4 in C57BL/6 mouse bone marrow neutrophils assessed as inhibition of PMA-stimulated neutrophil extracellular trap formation preincub...

J Med Chem 58: 1337-44 (2015)


Article DOI: 10.1021/jm501636x
BindingDB Entry DOI: 10.7270/Q2ST7RJZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%