Found 49 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50042847
(CHEMBL3098602)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N4O5/c21-20(22,23)12-5-4-6-13(11-12)24-18(30)14(7-2-1-3-8-17(29)27-32)26-19(31)15-9-10-16(28)25-15/h4-6,11,14-15,32H,1-3,7-10H2,(H,24,30)(H,25,28)(H,26,31)(H,27,29)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50042847
(CHEMBL3098602)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N4O5/c21-20(22,23)12-5-4-6-13(11-12)24-18(30)14(7-2-1-3-8-17(29)27-32)26-19(31)15-9-10-16(28)25-15/h4-6,11,14-15,32H,1-3,7-10H2,(H,24,30)(H,25,28)(H,26,31)(H,27,29)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50042847
(CHEMBL3098602)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N4O5/c21-20(22,23)12-5-4-6-13(11-12)24-18(30)14(7-2-1-3-8-17(29)27-32)26-19(31)15-9-10-16(28)25-15/h4-6,11,14-15,32H,1-3,7-10H2,(H,24,30)(H,25,28)(H,26,31)(H,27,29)/t14-,15+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50042848
(CHEMBL3098691)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O5/c24-16-12-11-15(21-16)19(27)22-14(9-5-2-6-10-17(25)23-28)18(26)20-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,28H,2,5-6,9-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50042845
(CHEMBL3353925)Show SMILES SCCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H25N3O3S/c22-16-11-10-15(20-16)18(24)21-14(9-5-2-6-12-25)17(23)19-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,25H,2,5-6,9-12H2,(H,19,23)(H,20,22)(H,21,24)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50042846
(CHEMBL3098604)Show SMILES Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C20H28N4O5/c1-13-6-5-7-14(12-13)21-19(27)15(8-3-2-4-9-18(26)24-29)23-20(28)16-10-11-17(25)22-16/h5-7,12,15-16,29H,2-4,8-11H2,1H3,(H,21,27)(H,22,25)(H,23,28)(H,24,26)/t15-,16+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50027520
(CHEMBL3353927)Show SMILES FC(F)(F)c1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C19H24F3N3O3S/c20-19(21,22)12-5-4-6-13(11-12)23-17(27)14(7-2-1-3-10-29)25-18(28)15-8-9-16(26)24-15/h4-6,11,14-15,29H,1-3,7-10H2,(H,23,27)(H,24,26)(H,25,28)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50027520
(CHEMBL3353927)Show SMILES FC(F)(F)c1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C19H24F3N3O3S/c20-19(21,22)12-5-4-6-13(11-12)23-17(27)14(7-2-1-3-10-29)25-18(28)15-8-9-16(26)24-15/h4-6,11,14-15,29H,1-3,7-10H2,(H,23,27)(H,24,26)(H,25,28)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50042845
(CHEMBL3353925)Show SMILES SCCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H25N3O3S/c22-16-11-10-15(20-16)18(24)21-14(9-5-2-6-12-25)17(23)19-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,25H,2,5-6,9-12H2,(H,19,23)(H,20,22)(H,21,24)/t14-,15+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50042849
(CHEMBL3098695)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H24N4O5/c23-15(22-27)10-6-2-5-9-13(21-18(26)14-11-16(24)20-14)17(25)19-12-7-3-1-4-8-12/h1,3-4,7-8,13-14,27H,2,5-6,9-11H2,(H,19,25)(H,20,24)(H,21,26)(H,22,23)/t13-,14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50042846
(CHEMBL3098604)Show SMILES Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C20H28N4O5/c1-13-6-5-7-14(12-13)21-19(27)15(8-3-2-4-9-18(26)24-29)23-20(28)16-10-11-17(25)22-16/h5-7,12,15-16,29H,2-4,8-11H2,1H3,(H,21,27)(H,22,25)(H,23,28)(H,24,26)/t15-,16+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50027520
(CHEMBL3353927)Show SMILES FC(F)(F)c1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C19H24F3N3O3S/c20-19(21,22)12-5-4-6-13(11-12)23-17(27)14(7-2-1-3-10-29)25-18(28)15-8-9-16(26)24-15/h4-6,11,14-15,29H,1-3,7-10H2,(H,23,27)(H,24,26)(H,25,28)/t14-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50042847
(CHEMBL3098602)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N4O5/c21-20(22,23)12-5-4-6-13(11-12)24-18(30)14(7-2-1-3-8-17(29)27-32)26-19(31)15-9-10-16(28)25-15/h4-6,11,14-15,32H,1-3,7-10H2,(H,24,30)(H,25,28)(H,26,31)(H,27,29)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50042845
(CHEMBL3353925)Show SMILES SCCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H25N3O3S/c22-16-11-10-15(20-16)18(24)21-14(9-5-2-6-12-25)17(23)19-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,25H,2,5-6,9-12H2,(H,19,23)(H,20,22)(H,21,24)/t14-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50042847
(CHEMBL3098602)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N4O5/c21-20(22,23)12-5-4-6-13(11-12)24-18(30)14(7-2-1-3-8-17(29)27-32)26-19(31)15-9-10-16(28)25-15/h4-6,11,14-15,32H,1-3,7-10H2,(H,24,30)(H,25,28)(H,26,31)(H,27,29)/t14-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50027520
(CHEMBL3353927)Show SMILES FC(F)(F)c1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C19H24F3N3O3S/c20-19(21,22)12-5-4-6-13(11-12)23-17(27)14(7-2-1-3-10-29)25-18(28)15-8-9-16(26)24-15/h4-6,11,14-15,29H,1-3,7-10H2,(H,23,27)(H,24,26)(H,25,28)/t14-,15+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50042846
(CHEMBL3098604)Show SMILES Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C20H28N4O5/c1-13-6-5-7-14(12-13)21-19(27)15(8-3-2-4-9-18(26)24-29)23-20(28)16-10-11-17(25)22-16/h5-7,12,15-16,29H,2-4,8-11H2,1H3,(H,21,27)(H,22,25)(H,23,28)(H,24,26)/t15-,16+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50027520
(CHEMBL3353927)Show SMILES FC(F)(F)c1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C19H24F3N3O3S/c20-19(21,22)12-5-4-6-13(11-12)23-17(27)14(7-2-1-3-10-29)25-18(28)15-8-9-16(26)24-15/h4-6,11,14-15,29H,1-3,7-10H2,(H,23,27)(H,24,26)(H,25,28)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50042845
(CHEMBL3353925)Show SMILES SCCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H25N3O3S/c22-16-11-10-15(20-16)18(24)21-14(9-5-2-6-12-25)17(23)19-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,25H,2,5-6,9-12H2,(H,19,23)(H,20,22)(H,21,24)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50042848
(CHEMBL3098691)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O5/c24-16-12-11-15(21-16)19(27)22-14(9-5-2-6-10-17(25)23-28)18(26)20-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,28H,2,5-6,9-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50042845
(CHEMBL3353925)Show SMILES SCCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H25N3O3S/c22-16-11-10-15(20-16)18(24)21-14(9-5-2-6-12-25)17(23)19-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,25H,2,5-6,9-12H2,(H,19,23)(H,20,22)(H,21,24)/t14-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50042846
(CHEMBL3098604)Show SMILES Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C20H28N4O5/c1-13-6-5-7-14(12-13)21-19(27)15(8-3-2-4-9-18(26)24-29)23-20(28)16-10-11-17(25)22-16/h5-7,12,15-16,29H,2-4,8-11H2,1H3,(H,21,27)(H,22,25)(H,23,28)(H,24,26)/t15-,16+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50042846
(CHEMBL3098604)Show SMILES Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C20H28N4O5/c1-13-6-5-7-14(12-13)21-19(27)15(8-3-2-4-9-18(26)24-29)23-20(28)16-10-11-17(25)22-16/h5-7,12,15-16,29H,2-4,8-11H2,1H3,(H,21,27)(H,22,25)(H,23,28)(H,24,26)/t15-,16+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50042846
(CHEMBL3098604)Show SMILES Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C20H28N4O5/c1-13-6-5-7-14(12-13)21-19(27)15(8-3-2-4-9-18(26)24-29)23-20(28)16-10-11-17(25)22-16/h5-7,12,15-16,29H,2-4,8-11H2,1H3,(H,21,27)(H,22,25)(H,23,28)(H,24,26)/t15-,16+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50042847
(CHEMBL3098602)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N4O5/c21-20(22,23)12-5-4-6-13(11-12)24-18(30)14(7-2-1-3-8-17(29)27-32)26-19(31)15-9-10-16(28)25-15/h4-6,11,14-15,32H,1-3,7-10H2,(H,24,30)(H,25,28)(H,26,31)(H,27,29)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50042848
(CHEMBL3098691)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O5/c24-16-12-11-15(21-16)19(27)22-14(9-5-2-6-10-17(25)23-28)18(26)20-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,28H,2,5-6,9-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50042849
(CHEMBL3098695)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H24N4O5/c23-15(22-27)10-6-2-5-9-13(21-18(26)14-11-16(24)20-14)17(25)19-12-7-3-1-4-8-12/h1,3-4,7-8,13-14,27H,2,5-6,9-11H2,(H,19,25)(H,20,24)(H,21,26)(H,22,23)/t13-,14-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50027520
(CHEMBL3353927)Show SMILES FC(F)(F)c1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C19H24F3N3O3S/c20-19(21,22)12-5-4-6-13(11-12)23-17(27)14(7-2-1-3-10-29)25-18(28)15-8-9-16(26)24-15/h4-6,11,14-15,29H,1-3,7-10H2,(H,23,27)(H,24,26)(H,25,28)/t14-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50042846
(CHEMBL3098604)Show SMILES Cc1cccc(NC(=O)[C@H](CCCCCC(=O)NO)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C20H28N4O5/c1-13-6-5-7-14(12-13)21-19(27)15(8-3-2-4-9-18(26)24-29)23-20(28)16-10-11-17(25)22-16/h5-7,12,15-16,29H,2-4,8-11H2,1H3,(H,21,27)(H,22,25)(H,23,28)(H,24,26)/t15-,16+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50042847
(CHEMBL3098602)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N4O5/c21-20(22,23)12-5-4-6-13(11-12)24-18(30)14(7-2-1-3-8-17(29)27-32)26-19(31)15-9-10-16(28)25-15/h4-6,11,14-15,32H,1-3,7-10H2,(H,24,30)(H,25,28)(H,26,31)(H,27,29)/t14-,15+/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50042849
(CHEMBL3098695)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H24N4O5/c23-15(22-27)10-6-2-5-9-13(21-18(26)14-11-16(24)20-14)17(25)19-12-7-3-1-4-8-12/h1,3-4,7-8,13-14,27H,2,5-6,9-11H2,(H,19,25)(H,20,24)(H,21,26)(H,22,23)/t13-,14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50042848
(CHEMBL3098691)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O5/c24-16-12-11-15(21-16)19(27)22-14(9-5-2-6-10-17(25)23-28)18(26)20-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,28H,2,5-6,9-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50042845
(CHEMBL3353925)Show SMILES SCCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H25N3O3S/c22-16-11-10-15(20-16)18(24)21-14(9-5-2-6-12-25)17(23)19-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,25H,2,5-6,9-12H2,(H,19,23)(H,20,22)(H,21,24)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50042849
(CHEMBL3098695)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H24N4O5/c23-15(22-27)10-6-2-5-9-13(21-18(26)14-11-16(24)20-14)17(25)19-12-7-3-1-4-8-12/h1,3-4,7-8,13-14,27H,2,5-6,9-11H2,(H,19,25)(H,20,24)(H,21,26)(H,22,23)/t13-,14-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50042848
(CHEMBL3098691)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O5/c24-16-12-11-15(21-16)19(27)22-14(9-5-2-6-10-17(25)23-28)18(26)20-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,28H,2,5-6,9-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50042848
(CHEMBL3098691)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O5/c24-16-12-11-15(21-16)19(27)22-14(9-5-2-6-10-17(25)23-28)18(26)20-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,28H,2,5-6,9-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50042848
(CHEMBL3098691)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H26N4O5/c24-16-12-11-15(21-16)19(27)22-14(9-5-2-6-10-17(25)23-28)18(26)20-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,28H,2,5-6,9-12H2,(H,20,26)(H,21,24)(H,22,27)(H,23,25)/t14-,15-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50042849
(CHEMBL3098695)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H24N4O5/c23-15(22-27)10-6-2-5-9-13(21-18(26)14-11-16(24)20-14)17(25)19-12-7-3-1-4-8-12/h1,3-4,7-8,13-14,27H,2,5-6,9-11H2,(H,19,25)(H,20,24)(H,21,26)(H,22,23)/t13-,14-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50042849
(CHEMBL3098695)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H24N4O5/c23-15(22-27)10-6-2-5-9-13(21-18(26)14-11-16(24)20-14)17(25)19-12-7-3-1-4-8-12/h1,3-4,7-8,13-14,27H,2,5-6,9-11H2,(H,19,25)(H,20,24)(H,21,26)(H,22,23)/t13-,14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50042849
(CHEMBL3098695)Show SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@@H]1CC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H24N4O5/c23-15(22-27)10-6-2-5-9-13(21-18(26)14-11-16(24)20-14)17(25)19-12-7-3-1-4-8-12/h1,3-4,7-8,13-14,27H,2,5-6,9-11H2,(H,19,25)(H,20,24)(H,21,26)(H,22,23)/t13-,14-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
MMDB
PDB
Article
PubMed
| n/a | n/a | 243 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| n/a | n/a | 258 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50042845
(CHEMBL3353925)Show SMILES SCCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C18H25N3O3S/c22-16-11-10-15(20-16)18(24)21-14(9-5-2-6-12-25)17(23)19-13-7-3-1-4-8-13/h1,3-4,7-8,14-15,25H,2,5-6,9-12H2,(H,19,23)(H,20,22)(H,21,24)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 281 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50027520
(CHEMBL3353927)Show SMILES FC(F)(F)c1cccc(NC(=O)[C@H](CCCCCS)NC(=O)[C@H]2CCC(=O)N2)c1 |r| Show InChI InChI=1S/C19H24F3N3O3S/c20-19(21,22)12-5-4-6-13(11-12)23-17(27)14(7-2-1-3-10-29)25-18(28)15-8-9-16(26)24-15/h4-6,11,14-15,29H,1-3,7-10H2,(H,23,27)(H,24,26)(H,25,28)/t14-,15+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 362 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 456 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
Article
PubMed
| n/a | n/a | 921 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
Curated by ChEMBL
| Assay Description
Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis |
Bioorg Med Chem Lett 25: 459-61 (2015)
Article DOI: 10.1016/j.bmcl.2014.12.051
BindingDB Entry DOI: 10.7270/Q2445P3R |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
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