Affinity Data by PubMed id=25589938

PubMed code 25589938

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50044091 (CHEMBL3356435) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of RSK2 (unknown origin) assessed as phosphorylation by Western lightning enhanced chemiluminescent reagent/HRP activity assay				ACS Med Chem Lett 6: 95-9 (2015) Article DOI: 10.1021/ml5004525 BindingDB Entry DOI: 10.7270/Q2RR20V0
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50241294 (CHEMBL240954 \| SL-0101 \| kaempferol 3-O-(3'',4''-d...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of RSK2 (unknown origin) assessed as phosphorylation by Western lightning enhanced chemiluminescent reagent/HRP activity assay				ACS Med Chem Lett 6: 95-9 (2015) Article DOI: 10.1021/ml5004525 BindingDB Entry DOI: 10.7270/Q2RR20V0
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50044090 (CHEMBL3356437) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of RSK2 (unknown origin) assessed as phosphorylation by Western lightning enhanced chemiluminescent reagent/HRP activity assay				ACS Med Chem Lett 6: 95-9 (2015) Article DOI: 10.1021/ml5004525 BindingDB Entry DOI: 10.7270/Q2RR20V0
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50044089 (CHEMBL3356439) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of RSK2 (unknown origin) assessed as phosphorylation by Western lightning enhanced chemiluminescent reagent/HRP activity assay				ACS Med Chem Lett 6: 95-9 (2015) Article DOI: 10.1021/ml5004525 BindingDB Entry DOI: 10.7270/Q2RR20V0
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50044088 (CHEMBL3356441) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Inhibition of RSK2 (unknown origin) assessed as phosphorylation by Western lightning enhanced chemiluminescent reagent/HRP activity assay				ACS Med Chem Lett 6: 95-9 (2015) Article DOI: 10.1021/ml5004525 BindingDB Entry DOI: 10.7270/Q2RR20V0
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%