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PubMed code 25614117

Compile data set for download or QSAR
Found 37 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM167911
PNG
(N,N-diethylcarbamic acid-4-(5,6,7-trimethoxy-4-oxo...)
Show SMILES CCN(CC)C(=O)Oc1ccc(cc1)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C23H25NO7/c1-6-24(7-2)23(26)30-15-10-8-14(9-11-15)17-12-16(25)20-18(31-17)13-19(27-3)21(28-4)22(20)29-5/h8-13H,6-7H2,1-5H3
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n/an/a 340n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM167912
PNG
(N,N-diethylcarbamic acid-4-(5-hydroxy-6,7-dimethox...)
Show SMILES CCN(CC)C(=O)Oc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C22H23NO7/c1-5-23(6-2)22(26)29-14-9-7-13(8-10-14)16-11-15(24)19-17(30-16)12-18(27-3)21(28-4)20(19)25/h7-12,25H,5-6H2,1-4H3
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n/an/a 570n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064040
PNG
(CHEMBL3401006)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(=O)N2CCN(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C30H30N2O7/c1-35-26-18-25-27(29(37-3)28(26)36-2)23(33)17-24(39-25)21-9-11-22(12-10-21)38-30(34)32-15-13-31(14-16-32)19-20-7-5-4-6-8-20/h4-12,17-18H,13-16,19H2,1-3H3
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n/an/a 1.04E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064054
PNG
(CHEMBL3401001)
Show SMILES CCN(C)C(=O)Oc1ccc(cc1)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C22H23NO7/c1-6-23(2)22(25)29-14-9-7-13(8-10-14)16-11-15(24)19-17(30-16)12-18(26-3)20(27-4)21(19)28-5/h7-12H,6H2,1-5H3
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n/an/a 1.54E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064038
PNG
(CHEMBL3401008)
Show SMILES CCN(C)C(=O)Oc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C21H21NO7/c1-5-22(2)21(25)28-13-8-6-12(7-9-13)15-10-14(23)18-16(29-15)11-17(26-3)20(27-4)19(18)24/h6-11,24H,5H2,1-4H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064028
PNG
(CHEMBL3401013)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(OC(=O)N2CCN(C)CC2)cc1
Show InChI InChI=1S/C23H24N2O7/c1-24-8-10-25(11-9-24)23(28)31-15-6-4-14(5-7-15)17-12-16(26)20-18(32-17)13-19(29-2)22(30-3)21(20)27/h4-7,12-13,27H,8-11H2,1-3H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM10620
PNG
((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Show SMILES [H][C@@](C)(N(C)C)c1cccc(OC(=O)N(C)CC)c1
Show InChI InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1
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n/an/a 5.60E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064002
PNG
(CHEMBL3401017)
Show SMILES CCN(CC)C(=O)Oc1cccc(c1)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C23H25NO7/c1-6-24(7-2)23(26)30-15-10-8-9-14(11-15)17-12-16(25)20-18(31-17)13-19(27-3)21(28-4)22(20)29-5/h8-13H,6-7H2,1-5H3
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n/an/a 6.11E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064001
PNG
(CHEMBL3401016)
Show SMILES CCN(C)C(=O)Oc1cccc(c1)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C22H23NO7/c1-6-23(2)22(25)29-14-9-7-8-13(10-14)16-11-15(24)19-17(30-16)12-18(26-3)20(27-4)21(19)28-5/h7-12H,6H2,1-5H3
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n/an/a 7.37E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064056
PNG
(CHEMBL3401000)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(=O)N(C)C)cc1
Show InChI InChI=1S/C21H21NO7/c1-22(2)21(24)28-13-8-6-12(7-9-13)15-10-14(23)18-16(29-15)11-17(25-3)19(26-4)20(18)27-5/h6-11H,1-5H3
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n/an/a 8.24E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064023
PNG
(CHEMBL3401014)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(OC(=O)N2CCN(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C29H28N2O7/c1-35-25-17-24-26(27(33)28(25)36-2)22(32)16-23(38-24)20-8-10-21(11-9-20)37-29(34)31-14-12-30(13-15-31)18-19-6-4-3-5-7-19/h3-11,16-17,33H,12-15,18H2,1-2H3
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n/an/a 9.25E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064059
PNG
(CHEMBL3401025)
Show SMILES CCN(CC)C(=O)Oc1cccc(c1)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C22H23NO7/c1-5-23(6-2)22(26)29-14-9-7-8-13(10-14)16-11-15(24)19-17(30-16)12-18(27-3)21(28-4)20(19)25/h7-12,25H,5-6H2,1-4H3
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n/an/a 1.03E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064041
PNG
(CHEMBL3401005)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(=O)N2CCN(C)CC2)cc1
Show InChI InChI=1S/C24H26N2O7/c1-25-9-11-26(12-10-25)24(28)32-16-7-5-15(6-8-16)18-13-17(27)21-19(33-18)14-20(29-2)22(30-3)23(21)31-4/h5-8,13-14H,9-12H2,1-4H3
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n/an/a 1.14E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064053
PNG
(CHEMBL3401003)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(=O)N(C(C)C)C(C)C)cc1
Show InChI InChI=1S/C25H29NO7/c1-14(2)26(15(3)4)25(28)32-17-10-8-16(9-11-17)19-12-18(27)22-20(33-19)13-21(29-5)23(30-6)24(22)31-7/h8-15H,1-7H3
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n/an/a 1.37E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064058
PNG
(CHEMBL3401024)
Show SMILES CCN(C)C(=O)Oc1cccc(c1)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C21H21NO7/c1-5-22(2)21(25)28-13-8-6-7-12(9-13)15-10-14(23)18-16(29-15)11-17(26-3)20(27-4)19(18)24/h6-11,24H,5H2,1-4H3
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n/an/a 1.48E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064039
PNG
(CHEMBL3401007)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(OC(=O)N(C)C)cc1
Show InChI InChI=1S/C20H19NO7/c1-21(2)20(24)27-12-7-5-11(6-8-12)14-9-13(22)17-15(28-14)10-16(25-3)19(26-4)18(17)23/h5-10,23H,1-4H3
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n/an/a 1.73E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064031
PNG
(CHEMBL3401012)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(OC(=O)N2CCCCC2)cc1
Show InChI InChI=1S/C23H23NO7/c1-28-19-13-18-20(21(26)22(19)29-2)16(25)12-17(31-18)14-6-8-15(9-7-14)30-23(27)24-10-4-3-5-11-24/h6-9,12-13,26H,3-5,10-11H2,1-2H3
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n/an/a 1.78E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064049
PNG
(CHEMBL3401004)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(=O)N2CCCCC2)cc1
Show InChI InChI=1S/C24H25NO7/c1-28-20-14-19-21(23(30-3)22(20)29-2)17(26)13-18(32-19)15-7-9-16(10-8-15)31-24(27)25-11-5-4-6-12-25/h7-10,13-14H,4-6,11-12H2,1-3H3
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n/an/a 2.12E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064134
PNG
(CHEMBL3401029)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1cccc(OC(=O)N2CCN(C)CC2)c1
Show InChI InChI=1S/C23H24N2O7/c1-24-7-9-25(10-8-24)23(28)31-15-6-4-5-14(11-15)17-12-16(26)20-18(32-17)13-19(29-2)22(30-3)21(20)27/h4-6,11-13,27H,7-10H2,1-3H3
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n/an/a 2.33E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064057
PNG
(CHEMBL3401023)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1cccc(OC(=O)N(C)C)c1
Show InChI InChI=1S/C20H19NO7/c1-21(2)20(24)27-12-7-5-6-11(8-12)14-9-13(22)17-15(28-14)10-16(25-3)19(26-4)18(17)23/h5-10,23H,1-4H3
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n/an/a 2.57E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064006
PNG
(CHEMBL3401021)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1cccc(OC(=O)N2CCN(C)CC2)c1
Show InChI InChI=1S/C24H26N2O7/c1-25-8-10-26(11-9-25)24(28)32-16-7-5-6-15(12-16)18-13-17(27)21-19(33-18)14-20(29-2)22(30-3)23(21)31-4/h5-7,12-14H,8-11H2,1-4H3
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n/an/a 3.12E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064022
PNG
(CHEMBL3401015)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1cccc(OC(=O)N(C)C)c1
Show InChI InChI=1S/C21H21NO7/c1-22(2)21(24)28-13-8-6-7-12(9-13)15-10-14(23)18-16(29-15)11-17(25-3)19(26-4)20(18)27-5/h6-11H,1-5H3
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n/an/a 3.73E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064005
PNG
(CHEMBL3401020)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1cccc(OC(=O)N2CCCCC2)c1
Show InChI InChI=1S/C24H25NO7/c1-28-20-14-19-21(23(30-3)22(20)29-2)17(26)13-18(32-19)15-8-7-9-16(12-15)31-24(27)25-10-5-4-6-11-25/h7-9,12-14H,4-6,10-11H2,1-3H3
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n/an/a 4.57E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064135
PNG
(CHEMBL3401030)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1cccc(OC(=O)N2CCN(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C29H28N2O7/c1-35-25-17-24-26(27(33)28(25)36-2)22(32)16-23(38-24)20-9-6-10-21(15-20)37-29(34)31-13-11-30(12-14-31)18-19-7-4-3-5-8-19/h3-10,15-17,33H,11-14,18H2,1-2H3
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n/an/a 5.17E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064052
PNG
(CHEMBL3400158)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(=O)N2CCOCC2)cc1
Show InChI InChI=1S/C23H23NO8/c1-27-19-13-18-20(22(29-3)21(19)28-2)16(25)12-17(32-18)14-4-6-15(7-5-14)31-23(26)24-8-10-30-11-9-24/h4-7,12-13H,8-11H2,1-3H3
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n/an/a 6.83E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064021
PNG
(CHEMBL3401022)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1cccc(OC(=O)N2CCN(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C30H30N2O7/c1-35-26-18-25-27(29(37-3)28(26)36-2)23(33)17-24(39-25)21-10-7-11-22(16-21)38-30(34)32-14-12-31(13-15-32)19-20-8-5-4-6-9-20/h4-11,16-18H,12-15,19H2,1-3H3
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n/an/a 8.71E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064003
PNG
(CHEMBL3401018)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1cccc(OC(=O)N(C(C)C)C(C)C)c1
Show InChI InChI=1S/C25H29NO7/c1-14(2)26(15(3)4)25(28)32-17-10-8-9-16(11-17)19-12-18(27)22-20(33-19)13-21(29-5)23(30-6)24(22)31-7/h8-15H,1-7H3
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n/an/a 8.75E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064087
PNG
(CHEMBL3401026)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1cccc(OC(=O)N(C(C)C)C(C)C)c1
Show InChI InChI=1S/C24H27NO7/c1-13(2)25(14(3)4)24(28)31-16-9-7-8-15(10-16)18-11-17(26)21-19(32-18)12-20(29-5)23(30-6)22(21)27/h7-14,27H,1-6H3
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n/an/a 9.65E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064136
PNG
(CHEBI:79510 | CHEMBL74490 | NSC-53906)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(O)cc1
Show InChI InChI=1S/C18H16O6/c1-21-15-9-14-16(18(23-3)17(15)22-2)12(20)8-13(24-14)10-4-6-11(19)7-5-10/h4-9,19H,1-3H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064102
PNG
(CHEMBL3401027)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1cccc(OC(=O)N2CCOCC2)c1
Show InChI InChI=1S/C22H21NO8/c1-27-18-12-17-19(20(25)21(18)28-2)15(24)11-16(31-17)13-4-3-5-14(10-13)30-22(26)23-6-8-29-9-7-23/h3-5,10-12,25H,6-9H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064004
PNG
(CHEMBL3401019)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1cccc(OC(=O)N2CCOCC2)c1
Show InChI InChI=1S/C23H23NO8/c1-27-19-13-18-20(22(29-3)21(19)28-2)16(25)12-17(32-18)14-5-4-6-15(11-14)31-23(26)24-7-9-30-10-8-24/h4-6,11-13H,7-10H2,1-3H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064133
PNG
(CHEMBL3401028)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1cccc(OC(=O)N2CCCCC2)c1
Show InChI InChI=1S/C23H23NO7/c1-28-19-13-18-20(21(26)22(19)29-2)16(25)12-17(31-18)14-7-6-8-15(11-14)30-23(27)24-9-4-3-5-10-24/h6-8,11-13,26H,3-5,9-10H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064033
PNG
(CHEMBL3401011)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(OC(=O)N2CCOCC2)cc1
Show InChI InChI=1S/C22H21NO8/c1-27-18-12-17-19(20(25)21(18)28-2)15(24)11-16(31-17)13-3-5-14(6-4-13)30-22(26)23-7-9-29-10-8-23/h3-6,11-12,25H,7-10H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064037
PNG
(CHEMBL3401010)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(OC(=O)N(C(C)C)C(C)C)cc1
Show InChI InChI=1S/C24H27NO7/c1-13(2)25(14(3)4)24(28)31-16-9-7-15(8-10-16)18-11-17(26)21-19(32-18)12-20(29-5)23(30-6)22(21)27/h7-14,27H,1-6H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064137
PNG
(CHEMBL3401031)
Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1cccc(O)c1
Show InChI InChI=1S/C18H16O6/c1-21-15-9-14-16(18(23-3)17(15)22-2)12(20)8-13(24-14)10-5-4-6-11(19)7-10/h4-9,19H,1-3H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50049394
PNG
(5,4'-Dihydroxy-6,7-dimethoxyflavone | 5-Hydroxy-2-...)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(O)cc1
Show InChI InChI=1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Rattus norvegicus (rat))		BDBM50064138
PNG
(CHEMBL3401032)
Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OC)-c1cccc(O)c1
Show InChI InChI=1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-4-3-5-10(18)6-9/h3-8,18,20H,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman method

Bioorg Med Chem 23: 668-80 (2015)


Article DOI: 10.1016/j.bmc.2015.01.005
BindingDB Entry DOI: 10.7270/Q24T6M2R
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%