Affinity Data by PubMed id=25638496

PubMed code 25638496

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50118225 (ARL 69931MX \| Adenosine triphosphate derivative \| ...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of ADP-induced aggregation preincubated for 5 mins followed by...				Bioorg Med Chem 23: 3880-906 (2015) Article DOI: 10.1016/j.bmc.2014.12.034 BindingDB Entry DOI: 10.7270/Q2MC91S4
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50084140 (4-((S)-Amino-carboxy-methyl)-3-methyl-benzoic acid...) Show SMILES Cc1cc(ccc1[C@H](N)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR1alpha expressed in syrian hamster AV-12 cells assessed as inhibition of quisqualate-induced phosphoinos...				Bioorg Med Chem 23: 3880-906 (2015) Article DOI: 10.1016/j.bmc.2014.12.034 BindingDB Entry DOI: 10.7270/Q2MC91S4
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%