Affinity Data by PubMed id=2571729

PubMed code 2571729

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017519 (1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against 5-hydroxytryptamine 1A receptor receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligand				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50017519 (1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]-8-OH-DPAT as the radioligand				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50044236 (CHEMBL303339 \| Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...) Show SMILES CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50017519 (1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against Dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligand				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50017520 ((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...) Show SMILES CN(C)C1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50044235 (CHEMBL292274 \| Dimethyl-(S)-6,7,8,9-tetrahydro-3H-...) Show SMILES CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50044236 (CHEMBL303339 \| Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...) Show SMILES CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017520 ((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...) Show SMILES CN(C)C1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against Dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50044235 (CHEMBL292274 \| Dimethyl-(S)-6,7,8,9-tetrahydro-3H-...) Show SMILES CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50017520 ((+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...) Show SMILES CN(C)C1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50044236 (CHEMBL303339 \| Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...) Show SMILES CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50044235 (CHEMBL292274 \| Dimethyl-(S)-6,7,8,9-tetrahydro-3H-...) Show SMILES CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligand.				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding activity against dopamine D1 receptor from homogenized rat brain, using [3H]SCH-23390 as the radioligand				J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%