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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Histone deacetylase 8 (Homo sapiens (Human)) | BDBM50089085 (CHEMBL3577694) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC cla... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 8 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC cla... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50089085 (CHEMBL3577694) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 6 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089085 (CHEMBL3577694) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089101 (CHEMBL3577691) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089086 (CHEMBL3577704) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089090 (CHEMBL3577697) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089091 (CHEMBL3577696) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089093 (CHEMBL3577693) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089088 (CHEMBL3577699) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 275 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 2 (Homo sapiens (Human)) | BDBM50089085 (CHEMBL3577694) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 275 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC sub... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089100 (CHEMBL3577692) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 321 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089089 (CHEMBL3577698) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 527 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089087 (CHEMBL3577703) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50089092 (CHEMBL3577695) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fujian University of Traditional Chinese Medicine Curated by ChEMBL | Assay Description Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 af... | ACS Med Chem Lett 6: 239-43 (2015) Article DOI: 10.1021/ml500327q BindingDB Entry DOI: 10.7270/Q23F4RCK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
