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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DNA topoisomerase 2-alpha (Homo sapiens (Human)) | BDBM50089640 (CHEMBL3578326) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Pharmaceutical Technology (Biotechnology), Department of Pharmacoinformatics, and Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL | Assay Description Inhibition of human topoisomerase 2alpha assessed as reduction in enzyme-mediated kinetoplast DNA decatenation incubated for 30 mins by agarose gel e... | ACS Med Chem Lett 6: 481-5 (2015) Article DOI: 10.1021/acsmedchemlett.5b00040 BindingDB Entry DOI: 10.7270/Q2S1848C | |||||||||||
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