Affinity Data by PubMed id=26078011

PubMed code 26078011

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50095990 (CHEMBL3593282) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of Amyloid beta (1 to 42) (unknown origin) aggregation assessed as amount of fibrils formation after 2 hrs by thioflavin T based spectrofl...				Bioorg Med Chem 23: 4688-98 (2015) Article DOI: 10.1016/j.bmc.2015.05.050 BindingDB Entry DOI: 10.7270/Q29888RC
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50095989 (CHEMBL3593279) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of Amyloid beta (1 to 42) (unknown origin) aggregation assessed as amount of fibrils formation after 2 hrs by thioflavin T based spectrofl...				Bioorg Med Chem 23: 4688-98 (2015) Article DOI: 10.1016/j.bmc.2015.05.050 BindingDB Entry DOI: 10.7270/Q29888RC
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM75309 ((2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of Amyloid beta (1 to 42) (unknown origin) aggregation assessed as amount of fibrils formation after 2 hrs by thioflavin T based spectrofl...				Bioorg Med Chem 23: 4688-98 (2015) Article DOI: 10.1016/j.bmc.2015.05.050 BindingDB Entry DOI: 10.7270/Q29888RC
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50095988 (CHEMBL3593278) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of Amyloid beta (1 to 42) (unknown origin) aggregation assessed as amount of fibrils formation after 2 hrs by thioflavin T based spectrofl...				Bioorg Med Chem 23: 4688-98 (2015) Article DOI: 10.1016/j.bmc.2015.05.050 BindingDB Entry DOI: 10.7270/Q29888RC
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50095986 (CHEMBL3593277) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of Amyloid beta (1 to 40) (unknown origin) aggregation assessed as amount of fibrils formation at 100 uM after 2 hrs by thioflavin T based...				Bioorg Med Chem 23: 4688-98 (2015) Article DOI: 10.1016/j.bmc.2015.05.050 BindingDB Entry DOI: 10.7270/Q29888RC
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50095987 (CHEMBL3593280) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of Amyloid beta (1 to 40) (unknown origin) aggregation assessed as amount of fibrils formation at 100 uM after 2 hrs by thioflavin T based...				Bioorg Med Chem 23: 4688-98 (2015) Article DOI: 10.1016/j.bmc.2015.05.050 BindingDB Entry DOI: 10.7270/Q29888RC
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50095985 (CHEMBL3593276) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibition of Amyloid beta (1 to 40) (unknown origin) aggregation assessed as amount of fibrils formation at 100 uM after 2 hrs by thioflavin T based...				Bioorg Med Chem 23: 4688-98 (2015) Article DOI: 10.1016/j.bmc.2015.05.050 BindingDB Entry DOI: 10.7270/Q29888RC
Universit£ degli Studi di Torino Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%